{"hash":"2209048702821896550","title":"Translational control and protein homeostasis","description":"This cluster is driven by translation as a core function (GO:0006412) and includes terms related to regulating protein turnover (negative regulation of ubiquitin ligase activity and ubiquitin-dependent catabolic processes) and protein stability, with links to cell cycle regulation and p53-mediated signaling, indicating a theme around controlling protein synthesis, stability, and cell-cycle\u2013associated stress responses.","confidence":"Medium","size":6,"edges":15,"triangles":20,"max_degree":5,"top_function":null,"members":[{"accession":"XP_002714487.1","go_terms":["GO:0032986","GO:0071158","GO:0072717","GO:2000059","GO:0050821","GO:1904667","GO:1901798","GO:0006412","GO:0071157"]},{"accession":"XP_017197689.1","go_terms":["GO:0006450","GO:0034337","GO:0000462","GO:0033120","GO:0046677","GO:0000372","GO:0006412"]},{"accession":"XP_008265846.1","go_terms":["GO:0006412"]},{"accession":"XP_008255683.1","go_terms":["GO:0097428","GO:0016226"]},{"accession":"XP_002714464.1","go_terms":["GO:0002181","GO:1990090","GO:0032543"]},{"accession":"XP_002715046.1","go_terms":["GO:0006412"]}],"graph":[["XP_002714487.1","XP_002714464.1",0.894],["XP_002714487.1","XP_002715046.1",0.927],["XP_002714487.1","XP_008255683.1",0.975],["XP_002714487.1","XP_008265846.1",0.953],["XP_002714487.1","XP_017197689.1",0.794],["XP_002714464.1","XP_002715046.1",0.907],["XP_002714464.1","XP_008255683.1",0.979],["XP_002714464.1","XP_008265846.1",0.901],["XP_002714464.1","XP_017197689.1",0.526],["XP_017197689.1","XP_002715046.1",0.82],["XP_017197689.1","XP_008255683.1",0.965],["XP_017197689.1","XP_008265846.1",0.804],["XP_008255683.1","XP_002715046.1",0.969],["XP_008255683.1","XP_008265846.1",0.958],["XP_008265846.1","XP_002715046.1",0.955]],"all_go_terms":{"GO:1904667":1,"GO:0071157":1,"GO:0032986":1,"GO:0072717":1,"GO:2000059":1,"GO:1901798":1,"GO:0006412":4,"GO:0050821":1,"GO:0071158":1,"GO:0034337":1,"GO:0006450":1,"GO:0046677":1,"GO:0000462":1,"GO:0033120":1,"GO:0000372":1,"GO:0016226":1,"GO:0097428":1,"GO:1990090":1,"GO:0032543":1,"GO:0002181":1},"recipe_readded":[]}