{"hash":"664791844523735502","title":"ER stress\u2013driven immune activation and antigen presentation","description":"The top GO terms cluster around ER quality control (protein folding, ER unfolded protein response) alongside antigen processing with MHC class I, innate immune signaling, and phagocytosis. This suggests a functional module where ER stress responses feed into immune activation and antigen presentation, with some broader trafficking and cell-cycle roles present. Confidence in this cohesive theme is moderate due to a few general terms, but the core signals point to an ER-stress\u2013linked immune/antigen presentation program.","confidence":"Medium","size":3,"edges":3,"triangles":1,"max_degree":2,"top_function":null,"members":[{"accession":"XP_067963794.2","go_terms":["GO:0050766","GO:0033144","GO:0006457","GO:0030968","GO:0002502","GO:1900026","GO:2000510","GO:0090398","GO:0010204","GO:0048916","GO:1901224","GO:0007339","GO:0048387","GO:0048488","GO:0071157"]},{"accession":"XP_078622314.1","go_terms":["GO:0050766","GO:0033144","GO:0006457","GO:0030968","GO:0002502","GO:1900026","GO:2000510","GO:0090398","GO:0010204","GO:0048916","GO:1901224","GO:0007339","GO:0048387","GO:0048488","GO:0071157"]},{"accession":"XP_078638039.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]}],"graph":[["XP_078622314.1","XP_067963794.2",0.906],["XP_078622314.1","XP_078638039.1",0.9],["XP_078638039.1","XP_067963794.2",0.892]],"all_go_terms":{"GO:0006457":2,"GO:0048488":2,"GO:0002502":2,"GO:0030968":2,"GO:0090398":2,"GO:0010204":2,"GO:0050766":2,"GO:1900026":2,"GO:0033144":2,"GO:0071157":2,"GO:1901224":2,"GO:0048916":2,"GO:0048387":2,"GO:0007339":2,"GO:2000510":2,"GO:0090084":1,"GO:0071630":1,"GO:0070389":1,"GO:0009408":1,"GO:0070843":1,"GO:0006469":1,"GO:0036494":1,"GO:0006458":1,"GO:0006626":1,"GO:0006986":1,"GO:0030433":1,"GO:0046825":1,"GO:0045454":1,"GO:0032781":1,"GO:0034975":1,"GO:0097428":1,"GO:1900035":1,"GO:0071374":1,"GO:0035719":1,"GO:1901621":1,"GO:0006452":1,"GO:0051259":1,"GO:0031204":1,"GO:0001707":1,"GO:0006260":1},"recipe_readded":[]}