{"hash":"1815565281052646597","title":"Methylation-driven transcriptional regulation","description":"The top GO terms point to multiple methylation activities (histone H4-R3, arginine and glutamine methylation, rRNA methylation) and to transcriptional regulation (negative regulation of RNA polymerase II), with links to cell growth and cellular senescence and ribosome biogenesis. This combination suggests proteins involved in epigenetic/chromatin modification and transcriptional control, such as methyltransferases, rather than a single, distinct pathway. Some terms (tellurium ion response, cobalamin biosynthetic process) are less clearly connected and may reflect incidental annotations.","confidence":"Medium","size":3,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_067976132.2","go_terms":["GO:0016049","GO:0000122","GO:0009236","GO:0018364","GO:0090398","GO:0043985","GO:0031167","GO:0019919","GO:0046690"]},{"accession":"XP_067976134.2","go_terms":["GO:0016049","GO:0000122","GO:0009236","GO:0018364","GO:0090398","GO:0043985","GO:0031167","GO:0019919","GO:0046690"]},{"accession":"XP_067968122.2","go_terms":["GO:0070131","GO:0042254","GO:0042256","GO:1902626","GO:0006355","GO:0000463","GO:0070475","GO:0002127"]}],"graph":[],"all_go_terms":{"GO:0000122":2,"GO:0043985":2,"GO:0031167":2,"GO:0090398":2,"GO:0019919":2,"GO:0016049":2,"GO:0018364":2,"GO:0046690":2,"GO:0009236":2,"GO:0042254":1,"GO:0042256":1,"GO:0006355":1,"GO:0070131":1,"GO:0002127":1,"GO:1902626":1,"GO:0000463":1,"GO:0070475":1},"recipe_readded":["XP_067976965.1","XP_067961849.1","XP_067961853.1","XP_067961852.1","XP_067986263.1","XP_078625274.1","XP_078632370.1","XP_067962183.1","XP_067985636.1","XP_078623797.1","XP_067973490.1","XP_067973287.2","XP_067976352.2","XP_067977893.2","XP_078626150.1","XP_067978008.2","XP_067984243.2","XP_067963854.1","XP_067978776.2","XP_067982814.2"]}