{"hash":"379185411346523263","title":"Nucleotide metabolism and DNA replication initiation","description":"Based on the top GO terms, the cluster is dominated by nucleotide metabolism activities: purine ribonucleotide interconversion, various nucleotide phosphorylation and biosynthesis processes, and AMP salvage. The presence of DNA replication initiation suggests a link to supplying nucleotides for DNA synthesis or replication-related functions. The liver and brain development terms appear less coherent with the main signal and may be incidental annotations. Overall, the main theme is nucleotide metabolism with a possible connection to DNA replication.","confidence":"Medium","size":3,"edges":2,"triangles":0,"max_degree":2,"top_function":null,"members":[{"accession":"XP_011442696.3","go_terms":["GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0051301","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0034599","GO:0090296","GO:0072389","GO:0045041","GO:0016558","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617","GO:0090305","GO:0071897"]},{"accession":"XP_034313944.2","go_terms":["GO:0046039","GO:0044209","GO:0006270","GO:0046939","GO:0015951","GO:0001889","GO:0046041","GO:0046940","GO:0006172","GO:0007420","GO:0046705"]},{"accession":"XP_065940449.1","go_terms":["GO:0046039","GO:0044209","GO:0006270","GO:0046939","GO:0015951","GO:0001889","GO:0046041","GO:0046940","GO:0006172","GO:0007420","GO:0046705"]}],"graph":[["XP_034313944.2","XP_065940449.1",0.943],["XP_034313944.2","XP_011442696.3",0.743]],"all_go_terms":{"GO:2001171":1,"GO:0071712":1,"GO:1901800":1,"GO:0051301":1,"GO:0048219":1,"GO:0070987":1,"GO:0030968":1,"GO:0051260":1,"GO:0070651":1,"GO:1903715":1,"GO:0070682":1,"GO:0030433":1,"GO:1903724":1,"GO:0051013":1,"GO:0046034":1,"GO:0070407":1,"GO:0035617":1,"GO:0045899":1,"GO:0006406":1,"GO:0031117":1,"GO:0032968":1,"GO:1903007":1,"GO:0035494":1,"GO:0032979":1,"GO:0070389":1,"GO:0016562":1,"GO:0097352":1,"GO:0070370":1,"GO:0030420":1,"GO:1990171":1,"GO:0006272":1,"GO:0051131":1,"GO:0034599":1,"GO:0071897":1,"GO:0001824":1,"GO:0070914":1,"GO:0034551":1,"GO:0070676":1,"GO:0019079":1,"GO:0061641":1,"GO:0045041":1,"GO:0018279":1,"GO:0006260":1,"GO:0034214":1,"GO:0071218":1,"GO:0070414":1,"GO:0090296":1,"GO:0000733":1,"GO:0033314":1,"GO:0045053":1,"GO:0072389":1,"GO:0090261":1,"GO:0016485":1,"GO:0016558":1,"GO:0090305":1,"GO:0006888":1,"GO:0043335":1,"GO:2000158":1,"GO:0001319":1,"GO:0070842":1,"GO:0061738":1,"GO:0061166":1,"GO:1903862":1,"GO:0015951":2,"GO:0046940":2,"GO:0046039":2,"GO:0001889":2,"GO:0007420":2,"GO:0046041":2,"GO:0006172":2,"GO:0046705":2,"GO:0006270":2,"GO:0044209":2,"GO:0046939":2},"recipe_readded":[]}