{"hash":"1591099079712881720","title":"Acetyl-CoA production and fatty acid biosynthesis","description":"This set centers on acetyl-CoA production from multiple inputs (pyruvate, leucine) and its use in lipid synthesis. GO terms include pyruvate dehydrogenase activity, glycolysis, gluconeogenesis, malonyl-CoA biosynthesis, and long-chain fatty acid biosynthesis, plus leucine catabolism to acetyl-CoA. Together these indicate mitochondrial central carbon metabolism driving energy production and fatty acid biosynthesis. Confidence in this label is High.","confidence":"","size":9,"edges":35,"triangles":77,"max_degree":8,"top_function":null,"members":[{"accession":"NP_001292219.1","go_terms":["GO:0046381","GO:0042203","GO:1902600","GO:0010196","GO:0046232","GO:0015979","GO:0055114","GO:0006122"]},{"accession":"XP_011417512.1","go_terms":["GO:0006633","GO:0017000","GO:0009245","GO:1902987","GO:0009258","GO:0019878","GO:0043041","GO:0071555","GO:0070395","GO:0070400"]},{"accession":"XP_065929373.1","go_terms":["GO:0006355","GO:0006351"]},{"accession":"XP_011442596.2","go_terms":["GO:0006412"]},{"accession":"XP_011452610.3","go_terms":["GO:0043617","GO:0006086","GO:0000002","GO:0006099","GO:0006103","GO:0033512","GO:0006096","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_011411999.3","go_terms":["GO:0043617","GO:0006086","GO:0033512","GO:0006213","GO:0006099","GO:0006096","GO:0000002","GO:0006103","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006094"]},{"accession":"XP_011412451.3","go_terms":["GO:0043617","GO:0006086","GO:0033512","GO:0006213","GO:0006099","GO:0006096","GO:0000002","GO:0006103","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006094"]},{"accession":"XP_011413994.3","go_terms":["GO:0043617","GO:0006086","GO:0033512","GO:0006213","GO:0006099","GO:0006096","GO:0000002","GO:0006103","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006094"]},{"accession":"XP_011429906.3","go_terms":["GO:0051726","GO:1902476","GO:0060315","GO:1902000","GO:0010880","GO:0051881","GO:0045669","GO:0070527","GO:0009072","GO:0019852","GO:0009407","GO:0042594","GO:0014810","GO:0060316","GO:0006289","GO:0098869","GO:0010731","GO:0006749","GO:0045454","GO:0071243","GO:2001237","GO:0043508","GO:0033591","GO:0048147","GO:0002182","GO:0032930","GO:0018916","GO:0032869","GO:0006808","GO:0001516","GO:0051771","GO:0035726","GO:0043200","GO:0032355","GO:1901687","GO:0009734","GO:0042178","GO:0040008","GO:0002674","GO:0009636","GO:0043651","GO:0070458","GO:0032691","GO:0070664","GO:2000429","GO:0043124","GO:0007417","GO:1904706","GO:0032720","GO:0010804","GO:0007608","GO:0031100","GO:0071385","GO:2000469","GO:2000255","GO:0045471","GO:0014003","GO:0042994","GO:0071364","GO:0010044","GO:0071638","GO:0035732","GO:0071460","GO:0071672","GO:0070373","GO:0071285","GO:0003147","GO:0009263","GO:0071473","GO:0030416","GO:0080058","GO:1903026","GO:2000651","GO:0034599","GO:0055114"]}],"graph":[["XP_011417512.1","NP_001292219.1",0.986],["XP_011417512.1","XP_011411999.3",0.982],["XP_011417512.1","XP_011412451.3",0.982],["XP_011417512.1","XP_011413994.3",0.967],["XP_011417512.1","XP_011429906.3",0.988],["XP_011417512.1","XP_011442596.2",0.985],["XP_011417512.1","XP_011452610.3",0.981],["XP_011417512.1","XP_065929373.1",0.974],["XP_011413994.3","NP_001292219.1",0.963],["XP_011413994.3","XP_011411999.3",0.881],["XP_011413994.3","XP_011429906.3",0.985],["XP_011413994.3","XP_011442596.2",0.967],["XP_011413994.3","XP_011452610.3",0.661],["XP_011413994.3","XP_065929373.1",0.917],["NP_001292219.1","XP_011411999.3",0.985],["NP_001292219.1","XP_011412451.3",0.965],["NP_001292219.1","XP_011429906.3",0.988],["NP_001292219.1","XP_011442596.2",0.973],["NP_001292219.1","XP_011452610.3",0.975],["NP_001292219.1","XP_065929373.1",0.973],["XP_011412451.3","XP_011411999.3",0.894],["XP_011412451.3","XP_011429906.3",0.985],["XP_011412451.3","XP_011442596.2",0.98],["XP_011412451.3","XP_011452610.3",0.607],["XP_011412451.3","XP_065929373.1",0.952],["XP_065929373.1","XP_011442596.2",0.946],["XP_065929373.1","XP_011452610.3",0.982],["XP_065929373.1","XP_011411999.3",0.976],["XP_065929373.1","XP_011429906.3",0.986],["XP_011429906.3","XP_011411999.3",0.993],["XP_011429906.3","XP_011452610.3",0.987],["XP_011429906.3","XP_011442596.2",0.989],["XP_011452610.3","XP_011411999.3",0.837],["XP_011452610.3","XP_011442596.2",0.986],["XP_011411999.3","XP_011442596.2",0.985]],"all_go_terms":{"GO:0046381":1,"GO:0046232":1,"GO:0006122":1,"GO:1902600":1,"GO:0015979":1,"GO:0042203":1,"GO:0010196":1,"GO:0055114":2,"GO:0017000":1,"GO:0019878":1,"GO:0070395":1,"GO:1902987":1,"GO:0009245":1,"GO:0070400":1,"GO:0009258":1,"GO:0071555":1,"GO:0043041":1,"GO:0006633":1,"GO:0006355":1,"GO:0006351":1,"GO:0006412":1,"GO:0006086":4,"GO:0006213":4,"GO:0033512":4,"GO:0006096":4,"GO:0042759":4,"GO:0000002":4,"GO:2001295":4,"GO:0006094":4,"GO:0006103":4,"GO:0006552":4,"GO:0006814":4,"GO:0006099":4,"GO:0043617":4,"GO:0035726":1,"GO:0030416":1,"GO:1901687":1,"GO:0003147":1,"GO:0045454":1,"GO:0080058":1,"GO:0032869":1,"GO:0009263":1,"GO:0009072":1,"GO:0070458":1,"GO:0014003":1,"GO:0033591":1,"GO:0042178":1,"GO:2000429":1,"GO:0019852":1,"GO:0006749":1,"GO:2001237":1,"GO:0010880":1,"GO:0001516":1,"GO:0071672":1,"GO:0042994":1,"GO:0071473":1,"GO:0006808":1,"GO:0032691":1,"GO:0043124":1,"GO:0098869":1,"GO:0071285":1,"GO:0002674":1,"GO:0031100":1,"GO:0060316":1,"GO:0060315":1,"GO:1904706":1,"GO:0071243":1,"GO:1902000":1,"GO:0071385":1,"GO:0071638":1,"GO:0007608":1,"GO:0032720":1,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