{"hash":"15525233370091428","title":"Vitamin B6 biosynthesis and amino acid metabolism","description":"This cluster shows enrichment for pyridoxine biosynthetic process and multiple amino acid metabolism terms (L-serine biosynthesis, L-alanine catabolism, L-valine catabolism, L-kynurenine catabolic), suggesting a link to vitamin B6-related metabolism and amino acid turnover. Some other terms (DNA repair, cAMP response, Fe-S cluster iron incorporation) may reflect generalized cellular functions or cofactors, but the dominant signals point to B6 and amino acid metabolism.","confidence":"Medium","size":11,"edges":5,"triangles":0,"max_degree":5,"top_function":null,"members":[{"accession":"XP_011432584.3","go_terms":["GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265"]},{"accession":"XP_011441603.2","go_terms":["GO:0006571","GO:0009097","GO:0098706","GO:0015940","GO:0046392","GO:0009099","GO:0015677","GO:0019310","GO:0055129","GO:0006740","GO:0006574","GO:1902777","GO:0046487","GO:0055114","GO:0019322","GO:0042183","GO:0006813","GO:0042853","GO:0046177","GO:0030435","GO:0006098","GO:0009051","GO:0019521","GO:0006635","GO:0014823","GO:0042493","GO:0006096","GO:0042413","GO:0032868","GO:0045454","GO:0046676","GO:0071268","GO:0006730","GO:0042745","GO:0019510","GO:0001666","GO:1903758","GO:0002439","GO:0006564","GO:0033353","GO:0007584","GO:0006189","GO:0008615","GO:0009854"]},{"accession":"XP_011456884.1","go_terms":["GO:0006541","GO:0019552","GO:0006537","GO:0009094","GO:0072350","GO:0019551"]},{"accession":"XP_065934885.1","go_terms":["GO:0006281"]},{"accession":"XP_065938267.1","go_terms":[]},{"accession":"XP_011418025.3","go_terms":["GO:0032543"]},{"accession":"XP_011418526.3","go_terms":["GO:0055007","GO:0009791","GO:0009409","GO:0046949","GO:0042594","GO:0019254","GO:0042758","GO:0045329","GO:0007507","GO:0006574","GO:0033539","GO:0006552","GO:0033540","GO:0005978","GO:0006111","GO:0001889","GO:0051793","GO:0018896","GO:0006694","GO:0019439","GO:0055114","GO:1904070"]},{"accession":"XP_011425714.3","go_terms":["GO:0019677","GO:0015938","GO:0046067","GO:0046656","GO:0006203","GO:1901909","GO:1901907","GO:2000233","GO:0006382","GO:0046709","GO:0006281","GO:0015967","GO:0009240","GO:0046057","GO:2000781","GO:0034656","GO:0045337","GO:0016077","GO:0050992","GO:0071544","GO:1901639","GO:1901911"]},{"accession":"XP_011428638.3","go_terms":[]},{"accession":"XP_034305211.1","go_terms":["GO:0009443","GO:0009405","GO:0008615","GO:0002047","GO:0055114","GO:0042823"]},{"accession":"XP_065928229.1","go_terms":[]}],"graph":[["XP_011432584.3","XP_011425714.3",0.821],["XP_011432584.3","XP_011441603.2",0.821],["XP_011432584.3","XP_011456884.1",0.862],["XP_011432584.3","XP_065934885.1",0.52],["XP_011432584.3","XP_065938267.1",0.839]],"all_go_terms":{"GO:0051591":1,"GO:0018283":1,"GO:0034516":1,"GO:0097053":1,"GO:0051384":1,"GO:0043420":1,"GO:0008615":3,"GO:0006546":1,"GO:0019442":1,"GO:0009436":1,"GO:0044571":1,"GO:0034354":1,"GO:0070903":1,"GO:0007219":1,"GO:0042866":1,"GO:0042853":2,"GO:0019805":1,"GO:0019265":1,"GO:0006564":2,"GO:0046724":1,"GO:0019448":1,"GO:0019700":1,"GO:0071268":1,"GO:0009051":1,"GO:0006571":1,"GO:0045454":1,"GO:0014823":1,"GO:0019521":1,"GO:0019510":1,"GO:0006730":1,"GO:0006098":1,"GO:1902777":1,"GO:0006574":2,"GO:0055114":3,"GO:0002439":1,"GO:0006096":1,"GO:0042745":1,"GO:0030435":1,"GO:0046676":1,"GO:0042183":1,"GO:0006635":1,"GO:0046392":1,"GO:0046177":1,"GO:0006189":1,"GO:0015940":1,"GO:0055129":1,"GO:0015677":1,"GO:0019322":1,"GO:0009097":1,"GO:0046487":1,"GO:0001666":1,"GO:0006740":1,"GO:0032868":1,"GO:0019310":1,"GO:0007584":1,"GO:0033353":1,"GO:0042493":1,"GO:0098706":1,"GO:0006813":1,"GO:0009099":1,"GO:1903758":1,"GO:0009854":1,"GO:0042413":1,"GO:0072350":1,"GO:0019552":1,"GO:0009094":1,"GO:0006537":1,"GO:0006541":1,"GO:0019551":1,"GO:0006281":2,"GO:0032543":1,"GO:0019254":1,"GO:0033540":1,"GO:0051793":1,"GO:0001889":1,"GO:0009791":1,"GO:0006552":1,"GO:0042758":1,"GO:0005978":1,"GO:0006111":1,"GO:0009409":1,"GO:0006694":1,"GO:0033539":1,"GO:0055007":1,"GO:0018896":1,"GO:0019439":1,"GO:0046949":1,"GO:1904070":1,"GO:0007507":1,"GO:0042594":1,"GO:0045329":1,"GO:2000233":1,"GO:0006203":1,"GO:0046709":1,"GO:0045337":1,"GO:1901907":1,"GO:0006382":1,"GO:1901909":1,"GO:1901911":1,"GO:1901639":1,"GO:0019677":1,"GO:0050992":1,"GO:0009240":1,"GO:0071544":1,"GO:0046656":1,"GO:0015938":1,"GO:2000781":1,"GO:0046057":1,"GO:0015967":1,"GO:0046067":1,"GO:0016077":1,"GO:0034656":1,"GO:0002047":1,"GO:0009443":1,"GO:0042823":1,"GO:0009405":1},"recipe_readded":["XP_034326134.2","XP_011431272.1","XP_011429226.3","XP_011422953.3","XP_011449849.3","XP_011432159.3","XP_065925194.1","XP_011446564.3","XP_034311443.2","XP_011429335.3","XP_011421958.3","XP_065940511.1","XP_034328613.2","XP_034325241.2","XP_034302753.2","XP_034311190.1","XP_011445734.3","XP_065942414.1","XP_034298951.1","XP_011431080.3"]}