{"hash":"235133502937587442","title":"Amino acid catabolism and quinone metabolism","description":"This cluster is enriched for amino-acid catabolic processes (valine, alanine, kynurenine) and quinone biosynthesis (menaquinone, phylloquinone), with supporting signals for central-carbon metabolism (oxaloacetate) and lipid metabolism (fatty acid beta-oxidation). The presence of Notch signaling appears as an outlier. Overall, proteins seem to participate in diverse metabolic pathways, especially amino acid catabolism and quinone biosynthesis.","confidence":"Medium","size":18,"edges":153,"triangles":816,"max_degree":17,"top_function":"DNA-templated transcription","members":[{"accession":"XP_067929778.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_067930200.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_067944062.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_067942569.1","go_terms":["GO:0080093","GO:0048569","GO:0007584","GO:0006734","GO:0006099","GO:0051591","GO:0043627","GO:0006097","GO:0006096","GO:0001666","GO:0042542","GO:0042493","GO:0006107","GO:0009749","GO:0043065","GO:0055114","GO:0019244","GO:0006108"]},{"accession":"XP_067928144.1","go_terms":["GO:0006642","GO:0032504","GO:0046166","GO:0009658","GO:0061621","GO:0006098","GO:0080022","GO:0019563","GO:0006094"]},{"accession":"XP_067930416.1","go_terms":["GO:0006545","GO:0006567","GO:0006570","GO:0006569","GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265","GO:0009243","GO:0017000","GO:0009246","GO:0009245","GO:0071555","GO:0046677","GO:0009103"]},{"accession":"XP_067931266.1","go_terms":["GO:1904482","GO:0034340","GO:0035999","GO:0009113","GO:0046655","GO:0006565","GO:0006564","GO:0006231","GO:0051289","GO:0019264","GO:0017148","GO:0032259"]},{"accession":"XP_067931396.1","go_terms":["GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265","GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_067931564.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0014823","GO:0042493","GO:0042413","GO:0046676","GO:0032868","GO:0006574","GO:0019521","GO:0006096","GO:0045454"]},{"accession":"XP_067933671.1","go_terms":["GO:0006556","GO:0006730","GO:0009087","GO:0033353"]},{"accession":"XP_067935066.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_067935342.1","go_terms":["GO:0006545","GO:0006567","GO:0006570","GO:0006569","GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0007219","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0042853","GO:0097053","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_067936410.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_067936563.1","go_terms":["GO:2001234","GO:0071269","GO:1904831","GO:0051092","GO:0019450","GO:0070814","GO:0019346","GO:0019343","GO:0018272","GO:0044524","GO:0019279","GO:0043123","GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0007219","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0042853","GO:0097053","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_067941802.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_067945586.1","go_terms":["GO:0072756","GO:0009228","GO:0072747","GO:0046166","GO:0061732","GO:0006098","GO:0006096","GO:0055114","GO:0052865","GO:0005999","GO:0040008","GO:0010510","GO:0006006","GO:0016114","GO:0061034","GO:0006099"]},{"accession":"XP_067947143.1","go_terms":["GO:2001234","GO:0071269","GO:1904831","GO:0051092","GO:0019450","GO:0070814","GO:0019346","GO:0019343","GO:0018272","GO:0044524","GO:0019279","GO:0043123"]},{"accession":"XP_067948537.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]}],"graph":[["XP_067928144.1","XP_067929778.1",0.988],["XP_067928144.1","XP_067930200.1",0.958],["XP_067928144.1","XP_067930416.1",0.98],["XP_067928144.1","XP_067931266.1",0.982],["XP_067928144.1","XP_067931396.1",0.912],["XP_067928144.1","XP_067931564.1",0.956],["XP_067928144.1","XP_067933671.1",0.962],["XP_067928144.1","XP_067935066.1",0.96],["XP_067928144.1","XP_067935342.1",0.975],["XP_067928144.1","XP_067936410.1",0.983],["XP_067928144.1","XP_067936563.1",0.929],["XP_067928144.1","XP_067941802.1",0.978],["XP_067928144.1","XP_067942569.1",0.969],["XP_067928144.1","XP_067944062.1",0.959],["XP_067928144.1","XP_067945586.1",0.987],["XP_067928144.1","XP_067947143.1",0.951],["XP_067928144.1","XP_067948537.1",0.973],["XP_067947143.1","XP_067929778.1",0.97],["XP_067947143.1","XP_067930200.1",0.99],["XP_067947143.1","XP_067930416.1",0.98],["XP_067947143.1","XP_067931266.1",0.966],["XP_067947143.1","XP_067931396.1",0.923],["XP_067947143.1","XP_067931564.1",0.976],["XP_067947143.1","XP_067933671.1",0.952],["XP_067947143.1","XP_067935066.1",0.974],["XP_067947143.1","XP_067935342.1",0.975],["XP_067947143.1","XP_067936410.1",0.981],["XP_067947143.1","XP_067936563.1",0.941],["XP_067947143.1","XP_067941802.1",0.984],["XP_067947143.1","XP_067942569.1",0.964],["XP_067947143.1","XP_067944062.1",0.982],["XP_067947143.1","XP_067945586.1",0.993],["XP_067947143.1","XP_067948537.1",0.963],["XP_067930200.1","XP_067929778.1",0.99],["XP_067930200.1","XP_067930416.1",0.979],["XP_067930200.1","XP_067931266.1",0.99],["XP_067930200.1","XP_067931396.1",0.989],["XP_067930200.1","XP_067931564.1",0.985],["XP_067930200.1","XP_067933671.1",0.979],["XP_067930200.1","XP_067935066.1",0.979],["XP_067930200.1","XP_067935342.1",0.987],["XP_067930200.1","XP_067936410.1",0.99],["XP_067930200.1","XP_067936563.1",0.979],["XP_067930200.1","XP_067941802.1",0.983],["XP_067930200.1","XP_067942569.1",0.993],["XP_067930200.1","XP_067944062.1",0.984],["XP_067930200.1","XP_067945586.1",0.992],["XP_067930200.1","XP_067948537.1",0.989],["XP_067945586.1","XP_067929778.1",0.992],["XP_067945586.1","XP_067930416.1",0.978],["XP_067945586.1","XP_067931266.1",0.992],["XP_067945586.1","XP_067931396.1",0.992],["XP_067945586.1","XP_067931564.1",0.985],["XP_067945586.1","XP_067933671.1",0.951],["XP_067945586.1","XP_067935066.1",0.982],["XP_067945586.1","XP_067935342.1",0.991],["XP_067945586.1","XP_067936410.1",0.987],["XP_067945586.1","XP_067936563.1",0.987],["XP_067945586.1","XP_067941802.1",0.985],["XP_067945586.1","XP_067942569.1",0.683],["XP_067945586.1","XP_067944062.1",0.993],["XP_067945586.1","XP_067948537.1",0.991],["XP_067933671.1","XP_067929778.1",0.978],["XP_067933671.1","XP_067930416.1",0.95],["XP_067933671.1","XP_067931266.1",0.956],["XP_067933671.1","XP_067931396.1",0.932],["XP_067933671.1","XP_067931564.1",0.925],["XP_067933671.1","XP_067935342.1",0.976],["XP_067933671.1","XP_067935066.1",0.941],["XP_067933671.1","XP_067936410.1",0.989],["XP_067933671.1","XP_067936563.1",0.902],["XP_067933671.1","XP_067941802.1",0.979],["XP_067933671.1","XP_067942569.1",0.883],["XP_067933671.1","XP_067944062.1",0.982],["XP_067933671.1","XP_067948537.1",0.969],["XP_067929778.1","XP_067930416.1",0.985],["XP_067929778.1","XP_067931266.1",0.961],["XP_067929778.1","XP_067931396.1",0.952],["XP_067929778.1","XP_067931564.1",0.972],["XP_067929778.1","XP_067935066.1",0.972],["XP_067929778.1","XP_067935342.1",0.979],["XP_067929778.1","XP_067936410.1",0.986],["XP_067929778.1","XP_067936563.1",0.952],["XP_067929778.1","XP_067941802.1",0.986],["XP_067929778.1","XP_067942569.1",0.981],["XP_067929778.1","XP_067944062.1",0.976],["XP_067929778.1","XP_067948537.1",0.987],["XP_067931396.1","XP_067930416.1",0.981],["XP_067931396.1","XP_067931266.1",0.959],["XP_067931396.1","XP_067931564.1",0.954],["XP_067931396.1","XP_067935066.1",0.968],["XP_067931396.1","XP_067935342.1",0.972],["XP_067931396.1","XP_067936410.1",0.976],["XP_067931396.1","XP_067936563.1",0.84],["XP_067931396.1","XP_067941802.1",0.974],["XP_067931396.1","XP_067942569.1",0.959],["XP_067931396.1","XP_067944062.1",0.981],["XP_067931396.1","XP_067948537.1",0.985],["XP_067942569.1","XP_067930416.1",0.992],["XP_067942569.1","XP_067931266.1",0.979],["XP_067942569.1","XP_067931564.1",0.98],["XP_067942569.1","XP_067935066.1",0.944],["XP_067942569.1","XP_067935342.1",0.988],["XP_067942569.1","XP_067936410.1",0.983],["XP_067942569.1","XP_067936563.1",0.961],["XP_067942569.1","XP_067941802.1",0.992],["XP_067942569.1","XP_067948537.1",0.981],["XP_067942569.1","XP_067944062.1",0.987],["XP_067935342.1","XP_067930416.1",0.985],["XP_067935342.1","XP_067931266.1",0.984],["XP_067935342.1","XP_067931564.1",0.982],["XP_067935342.1","XP_067935066.1",0.983],["XP_067935342.1","XP_067936410.1",0.984],["XP_067935342.1","XP_067936563.1",0.97],["XP_067935342.1","XP_067941802.1",0.987],["XP_067935342.1","XP_067944062.1",0.984],["XP_067935342.1","XP_067948537.1",0.986],["XP_067936410.1","XP_067930416.1",0.984],["XP_067936410.1","XP_067931266.1",0.976],["XP_067936410.1","XP_067931564.1",0.981],["XP_067936410.1","XP_067935066.1",0.979],["XP_067936410.1","XP_067936563.1",0.957],["XP_067936410.1","XP_067941802.1",0.991],["XP_067936410.1","XP_067944062.1",0.984],["XP_067936410.1","XP_067948537.1",0.988],["XP_067931564.1","XP_067930416.1",0.982],["XP_067931564.1","XP_067931266.1",0.955],["XP_067931564.1","XP_067935066.1",0.962],["XP_067931564.1","XP_067936563.1",0.968],["XP_067931564.1","XP_067941802.1",0.985],["XP_067931564.1","XP_067944062.1",0.978],["XP_067931564.1","XP_067948537.1",0.982],["XP_067935066.1","XP_067930416.1",0.982],["XP_067935066.1","XP_067931266.1",0.977],["XP_067935066.1","XP_067941802.1",0.974],["XP_067935066.1","XP_067936563.1",0.957],["XP_067935066.1","XP_067948537.1",0.983],["XP_067935066.1","XP_067944062.1",0.984],["XP_067930416.1","XP_067931266.1",0.986],["XP_067930416.1","XP_067941802.1",0.979],["XP_067930416.1","XP_067936563.1",0.984],["XP_067930416.1","XP_067948537.1",0.984],["XP_067930416.1","XP_067944062.1",0.98],["XP_067944062.1","XP_067931266.1",0.963],["XP_067944062.1","XP_067936563.1",0.968],["XP_067944062.1","XP_067941802.1",0.986],["XP_067944062.1","XP_067948537.1",0.99],["XP_067941802.1","XP_067931266.1",0.979],["XP_067941802.1","XP_067936563.1",0.978],["XP_067941802.1","XP_067948537.1",0.985],["XP_067948537.1","XP_067931266.1",0.971],["XP_067948537.1","XP_067936563.1",0.952],["XP_067936563.1","XP_067931266.1",0.959]],"all_go_terms":{"GO:0006574":8,"GO:0010124":8,"GO:0009234":8,"GO:0006635":8,"GO:0017000":9,"GO:0042372":8,"GO:0080093":1,"GO:0006096":3,"GO:0019244":1,"GO:0006107":4,"GO:0006099":2,"GO:0007584":1,"GO:0042542":1,"GO:0055114":2,"GO:0043065":1,"GO:0006734":1,"GO:0051591":3,"GO:0006097":1,"GO:0006108":1,"GO:0048569":1,"GO:0043627":1,"GO:0001666":1,"GO:0042493":2,"GO:0009749":1,"GO:0032504":1,"GO:0080022":1,"GO:0006094":1,"GO:0046166":2,"GO:0006098":2,"GO:0019563":1,"GO:0061621":1,"GO:0009658":1,"GO:0006642":1,"GO:0006569":2,"GO:0043420":2,"GO:0009246":1,"GO:0018283":2,"GO:0009436":2,"GO:0006564":3,"GO:0006570":2,"GO:0019700":2,"GO:0019442":2,"GO:0046724":2,"GO:0019448":2,"GO:0046677":1,"GO:0042853":4,"GO:0071555":1,"GO:0006546":2,"GO:0034354":2,"GO:0042866":2,"GO:0006545":2,"GO:0051384":2,"GO:0007219":4,"GO:0044571":2,"GO:0070903":2,"GO:0019265":2,"GO:0019805":2,"GO:0008615":2,"GO:0009245":1,"GO:0009243":1,"GO:0009103":1,"GO:0097053":4,"GO:0006567":2,"GO:0034516":2,"GO:0032259":1,"GO:0046655":1,"GO:0051289":1,"GO:0006231":1,"GO:0034340":1,"GO:0017148":1,"GO:0009113":1,"GO:1904482":1,"GO:0006565":1,"GO:0019264":1,"GO:0035999":1,"GO:0009102":3,"GO:0019551":3,"GO:0006532":3,"GO:0009862":3,"GO:0006351":3,"GO:0019878":3,"GO:0015908":3,"GO:0006533":3,"GO:0019550":3,"GO:0006686":3,"GO:0019441":3,"GO:0032869":3,"GO:0019518":3,"GO:0006523":3,"GO:0006782":3,"GO:0033362":3,"GO:0046511":3,"GO:0034276":3,"GO:0033585":3,"GO:0042218":3,"GO:0006571":3,"GO:0033512":3,"GO:0006783":3,"GO:0009236":3,"GO:0009835":3,"GO:0055089":3,"GO:0000105":3,"GO:0046676":1,"GO:0042413":1,"GO:0014823":1,"GO:0019521":1,"GO:0032868":1,"GO:0045454":1,"GO:0009087":1,"GO:0006556":1,"GO:0006730":1,"GO:0033353":1,"GO:2001234":2,"GO:0018272":2,"GO:1904831":2,"GO:0019279":2,"GO:0019346":2,"GO:0051092":2,"GO:0070814":2,"GO:0019450":2,"GO:0071269":2,"GO:0043123":2,"GO:0019343":2,"GO:0044524":2,"GO:0052865":1,"GO:0010510":1,"GO:0009228":1,"GO:0061732":1,"GO:0072747":1,"GO:0061034":1,"GO:0006006":1,"GO:0072756":1,"GO:0005999":1,"GO:0016114":1,"GO:0040008":1},"recipe_readded":[]}