{"hash":"344151649303317889","title":"Nuclear transcription and chromatin maintenance","description":"This cluster centers on nuclear processes related to gene expression and chromatin regulation: DNA-templated transcription, mRNA export from the nucleus, and SAGA complex localization to transcription regulatory regions, with additional links to histone modification and genome stability (DNA repair, trinucleotide repeat maintenance) and proteasome/centrosome components. The shared theme is regulation of transcription in a chromatin context and maintenance of genome integrity, rather than a single cytosolic pathway.","confidence":"Medium","size":8,"edges":7,"triangles":0,"max_degree":7,"top_function":null,"members":[{"accession":"XP_060052175.1","go_terms":["GO:0040025","GO:0035753","GO:0030447","GO:0000724","GO:0043248","GO:0072742","GO:0016578","GO:0006406","GO:0006351"]},{"accession":"XP_060034118.1","go_terms":["GO:1904498","GO:2000251","GO:0035372","GO:0030866","GO:0007292","GO:0008360","GO:0061164","GO:0071420","GO:0070649","GO:0070060","GO:0071519","GO:0090140","GO:0071689","GO:0035320","GO:1904171","GO:1904670","GO:0006929","GO:0045010","GO:0051639","GO:0051758","GO:0010467","GO:0072092","GO:0055003","GO:0051295","GO:0051660","GO:0060292","GO:0040038"]},{"accession":"XP_007524699.2","go_terms":["GO:1901482","GO:1901481","GO:0006867","GO:0090452","GO:0090513","GO:0090515","GO:0090514","GO:0090517","GO:0090516","GO:0090518","GO:1990818","GO:0051365","GO:0048829","GO:0089707","GO:0061402","GO:0089708","GO:2000487","GO:0015824","GO:0015808"]},{"accession":"XP_007532636.1","go_terms":["GO:0071436","GO:0015878","GO:0015887","GO:1904659","GO:0008292","GO:0015798"]},{"accession":"XP_007535075.2","go_terms":[]},{"accession":"XP_007536755.2","go_terms":["GO:0060179","GO:0019226","GO:0001541","GO:0021521","GO:0071542","GO:0002052","GO:0007628","GO:0042487","GO:0035914","GO:0046661","GO:0021796","GO:0048599","GO:0060009","GO:0007290","GO:0008354","GO:0007141","GO:0006355","GO:0045835","GO:1900111","GO:1900114","GO:0048706","GO:0014807","GO:0030238","GO:0002176","GO:0060903","GO:2000020","GO:2000287","GO:1900107"]},{"accession":"XP_007516335.2","go_terms":["GO:0015693","GO:0035269","GO:0018279"]},{"accession":"XP_007523360.1","go_terms":["GO:0007124","GO:0015843","GO:0019740","GO:0001403","GO:0072488","GO:0060586","GO:0006808","GO:0070634","GO:0080181","GO:0015670"]}],"graph":[["XP_007516335.2","XP_060052175.1",0.697],["XP_007532636.1","XP_060052175.1",0.722],["XP_060052175.1","XP_007535075.2",0.883],["XP_060052175.1","XP_007536755.2",0.68],["XP_060052175.1","XP_060034118.1",0.795],["XP_060052175.1","XP_007523360.1",0.804],["XP_060052175.1","XP_007524699.2",0.731]],"all_go_terms":{"GO:0030447":1,"GO:0006351":1,"GO:0016578":1,"GO:0040025":1,"GO:0000724":1,"GO:0006406":1,"GO:0072742":1,"GO:0035753":1,"GO:0043248":1,"GO:0051660":1,"GO:0071689":1,"GO:0070649":1,"GO:0061164":1,"GO:1904670":1,"GO:0010467":1,"GO:0030866":1,"GO:2000251":1,"GO:0051758":1,"GO:0035320":1,"GO:1904171":1,"GO:0070060":1,"GO:0040038":1,"GO:0008360":1,"GO:0071519":1,"GO:0051639":1,"GO:0071420":1,"GO:0045010":1,"GO:0007292":1,"GO:0051295":1,"GO:0006929":1,"GO:0072092":1,"GO:0060292":1,"GO:0090140":1,"GO:0055003":1,"GO:1904498":1,"GO:0035372":1,"GO:0006867":1,"GO:1901482":1,"GO:0061402":1,"GO:0090516":1,"GO:0090518":1,"GO:2000487":1,"GO:0090517":1,"GO:0089707":1,"GO:0015808":1,"GO:0090452":1,"GO:0015824":1,"GO:1990818":1,"GO:1901481":1,"GO:0090515":1,"GO:0089708":1,"GO:0051365":1,"GO:0090514":1,"GO:0090513":1,"GO:0048829":1,"GO:0015878":1,"GO:0071436":1,"GO:0015887":1,"GO:0008292":1,"GO:0015798":1,"GO:1904659":1,"GO:0048599":1,"GO:0021521":1,"GO:0019226":1,"GO:0007628":1,"GO:1900111":1,"GO:0071542":1,"GO:0007141":1,"GO:0002052":1,"GO:1900107":1,"GO:0042487":1,"GO:1900114":1,"GO:0048706":1,"GO:0006355":1,"GO:0060179":1,"GO:0007290":1,"GO:0002176":1,"GO:0035914":1,"GO:0030238":1,"GO:2000020":1,"GO:0046661":1,"GO:0021796":1,"GO:0014807":1,"GO:0001541":1,"GO:0060903":1,"GO:0008354":1,"GO:2000287":1,"GO:0045835":1,"GO:0060009":1,"GO:0018279":1,"GO:0035269":1,"GO:0015693":1,"GO:0070634":1,"GO:0001403":1,"GO:0072488":1,"GO:0015843":1,"GO:0019740":1,"GO:0060586":1,"GO:0015670":1,"GO:0080181":1,"GO:0007124":1,"GO:0006808":1},"recipe_readded":[]}