{"hash":"287773706556024076","title":"DNA Damage Response with Transcription and Translation","description":"The cluster centers on transcriptional control (DNA-templated transcription, termination/elongation) and translation, with links to DNA damage signaling pathways (p53 mediator, gamma radiation, UV response). This suggests a cohesive stress-response module where DNA damage triggers transcriptional programs and regulates translation to manage cell fate. The presence of both transcriptional and translational GO terms alongside p53- and UV/gamma-related terms supports a single, unified DNA damage response cluster.","confidence":"High","size":9,"edges":36,"triangles":84,"max_degree":8,"top_function":null,"members":[{"accession":"XP_007536896.1","go_terms":["GO:1902164","GO:1902167","GO:0032784","GO:0006977","GO:1904803","GO:0042273","GO:0031564","GO:0071480","GO:0006354","GO:0006353","GO:0045727","GO:0006412"]},{"accession":"XP_060039363.1","go_terms":["GO:0042273","GO:0071480","GO:1902167","GO:0042256","GO:0006977","GO:0034644","GO:0045727","GO:1902164","GO:0006412","GO:1904803","GO:0032784","GO:0031564","GO:0006354","GO:0006353"]},{"accession":"XP_007522542.2","go_terms":["GO:0042273","GO:0071480","GO:1902167","GO:0042256","GO:0006977","GO:0034644","GO:0045727","GO:1902164","GO:0006412","GO:1904803","GO:0032784","GO:0031564","GO:0006354","GO:0006353"]},{"accession":"XP_007532322.1","go_terms":["GO:1903955","GO:0000463","GO:0000466","GO:0006412","GO:1903146"]},{"accession":"XP_007539039.2","go_terms":["GO:0070126","GO:0006412"]},{"accession":"XP_060050683.1","go_terms":["GO:0070126","GO:0006412"]},{"accession":"XP_060050684.1","go_terms":["GO:0070126","GO:0006412"]},{"accession":"XP_060051629.1","go_terms":["GO:1901194","GO:0006412"]},{"accession":"XP_007526297.1","go_terms":["GO:1901194","GO:0006412"]}],"graph":[["XP_007532322.1","XP_060051629.1",0.748],["XP_007532322.1","XP_060050683.1",0.974],["XP_007532322.1","XP_060050684.1",0.975],["XP_007532322.1","XP_007522542.2",0.833],["XP_007532322.1","XP_007526297.1",0.813],["XP_007532322.1","XP_007539039.2",0.978],["XP_007532322.1","XP_007536896.1",0.741],["XP_007532322.1","XP_060039363.1",0.841],["XP_060051629.1","XP_007536896.1",0.569],["XP_060051629.1","XP_007539039.2",0.964],["XP_060051629.1","XP_060039363.1",0.641],["XP_060051629.1","XP_060050683.1",0.963],["XP_060051629.1","XP_060050684.1",0.963],["XP_060051629.1","XP_007522542.2",0.638],["XP_060051629.1","XP_007526297.1",0.622],["XP_060050683.1","XP_007536896.1",0.969],["XP_060050683.1","XP_007539039.2",0.989],["XP_060050683.1","XP_060039363.1",0.966],["XP_060050683.1","XP_060050684.1",0.987],["XP_060050683.1","XP_007522542.2",0.957],["XP_060050683.1","XP_007526297.1",0.96],["XP_007536896.1","XP_060050684.1",0.968],["XP_007536896.1","XP_007522542.2",0.606],["XP_007536896.1","XP_007526297.1",0.659],["XP_007536896.1","XP_007539039.2",0.973],["XP_007536896.1","XP_060039363.1",0.633],["XP_007526297.1","XP_007522542.2",0.631],["XP_007526297.1","XP_007539039.2",0.966],["XP_007526297.1","XP_060039363.1",0.674],["XP_007526297.1","XP_060050684.1",0.964],["XP_060039363.1","XP_007539039.2",0.968],["XP_060039363.1","XP_060050684.1",0.966],["XP_060039363.1","XP_007522542.2",0.74],["XP_060050684.1","XP_007539039.2",0.989],["XP_060050684.1","XP_007522542.2",0.961],["XP_007539039.2","XP_007522542.2",0.961]],"all_go_terms":{"GO:0006353":3,"GO:0031564":3,"GO:1902167":3,"GO:0071480":3,"GO:0006412":9,"GO:0006977":3,"GO:0006354":3,"GO:1902164":3,"GO:0032784":3,"GO:1904803":3,"GO:0042273":3,"GO:0045727":3,"GO:0034644":2,"GO:0042256":2,"GO:0000463":1,"GO:1903955":1,"GO:1903146":1,"GO:0000466":1,"GO:0070126":3,"GO:1901194":2},"recipe_readded":[]}