{"hash":"1432496054280306305","title":"RNA metabolism and xenobiotic response","description":"This cluster centers on nucleic acid metabolism and post-transcriptional regulation, including regulation of mRNA stability and RNA phosphodiester bond processing, with additional signals of stress/detox pathways such as response to xenobiotic stimulus and redox homeostasis. A phosphoinositide signaling term connects to membrane-based signaling that can modulate stress responses, reinforcing a general RNA- and detox-associated theme. The renal water transport term appears less integrative and may be an outlier. Overall, the set seems to reflect RNA processing together with cellular defense against xenobiotics, supporting this label.","confidence":"Medium","size":5,"edges":1,"triangles":0,"max_degree":1,"top_function":"DNA recombination","members":[{"accession":"XP_055873070.1","go_terms":["GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0006310","GO:0080111","GO:0007568","GO:0071320","GO:0042493"]},{"accession":"XP_055879954.1","go_terms":["GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0006310","GO:0080111","GO:0007568","GO:0071320","GO:0042493"]},{"accession":"XP_055881658.1","go_terms":["GO:0000082","GO:0030324","GO:0007060","GO:0001662","GO:0000289","GO:0010032","GO:0045665","GO:0048515","GO:0010507","GO:0048136","GO:0048137","GO:0019827","GO:0071549","GO:0007112","GO:0016032","GO:0017148","GO:0002191","GO:0006412"]},{"accession":"XP_013073256.2","go_terms":["GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0006310","GO:0080111","GO:0007568","GO:0071320","GO:0042493"]},{"accession":"XP_055868423.1","go_terms":["GO:0075015","GO:0005989","GO:0060054","GO:0060058","GO:0007341","GO:0006486","GO:0048147","GO:0018146","GO:0060055","GO:0030879","GO:0060046","GO:0007339","GO:0006688","GO:0045136","GO:0021680","GO:0008542","GO:0002526","GO:0006029"]}],"graph":[["XP_055881658.1","XP_055868423.1",0.536]],"all_go_terms":{"GO:2001153":3,"GO:1903507":3,"GO:0046856":3,"GO:0043488":3,"GO:0045454":3,"GO:0007568":3,"GO:0044179":3,"GO:0006308":3,"GO:0042493":3,"GO:0090502":3,"GO:0070301":3,"GO:0006284":3,"GO:0006915":3,"GO:0014912":3,"GO:2000466":3,"GO:0071375":3,"GO:0003335":3,"GO:0071320":3,"GO:0080111":3,"GO:1900087":3,"GO:0006310":3,"GO:2000327":3,"GO:0048136":1,"GO:0071549":1,"GO:0002191":1,"GO:0045665":1,"GO:0019827":1,"GO:0016032":1,"GO:0010032":1,"GO:0010507":1,"GO:0006412":1,"GO:0000082":1,"GO:0048515":1,"GO:0030324":1,"GO:0007112":1,"GO:0048137":1,"GO:0017148":1,"GO:0001662":1,"GO:0007060":1,"GO:0000289":1,"GO:0060055":1,"GO:0005989":1,"GO:0060046":1,"GO:0007339":1,"GO:0060054":1,"GO:0007341":1,"GO:0018146":1,"GO:0021680":1,"GO:0002526":1,"GO:0006029":1,"GO:0075015":1,"GO:0060058":1,"GO:0006486":1,"GO:0006688":1,"GO:0008542":1,"GO:0048147":1,"GO:0045136":1,"GO:0030879":1},"recipe_readded":["XP_055878719.1","XP_013069940.2","XP_013062738.2","XP_055899258.1","XP_055879889.1","XP_055883509.1","XP_055895201.1","XP_055889328.1","XP_013070464.2","XP_013071062.2","XP_055879317.1","XP_055874432.1","XP_055873047.1","XP_055859612.1","XP_055859842.1","XP_055868752.1","XP_055898499.1","XP_055862008.1","XP_055877769.1","XP_055875012.1"]}