{"hash":"711366759982210118","title":"RNA processing and translation regulation","description":"These proteins cluster around RNA metabolism and control of translation, with strong representations of mRNA modification, spliceosome-mediated and alternative mRNA splicing, mRNA stabilization, and regulation of translational initiation (including IRES-dependent viral initiation and termination-reinitiation). The presence of small-subunit processome assembly further supports a link to ribonucleoprotein complexes involved in RNA processing and ribosome assembly, while blastocyst formation hints at developmental contexts where such RNA-based control is crucial. Overall, the cluster appears to group RNA processing/splicing factors and translation regulators.","confidence":"High","size":9,"edges":27,"triangles":37,"max_degree":7,"top_function":"regulatory ncRNA-mediated gene silencing","members":[{"accession":"XP_001628761.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_001641544.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_032220289.1","go_terms":[]},{"accession":"XP_032223593.2","go_terms":[]},{"accession":"XP_032226358.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071031","GO:0010587","GO:0019076","GO:0075713","GO:0019068","GO:0039702","GO:0000398","GO:0030260","GO:0039651","GO:0015074"]},{"accession":"XP_032232864.1","go_terms":["GO:0006924","GO:0006458","GO:0006986","GO:0000002","GO:0000740","GO:0006260","GO:0042787","GO:0006626","GO:0035719","GO:0042026","GO:0030433","GO:0009408","GO:1900035","GO:1905259","GO:0034975","GO:0010198","GO:0090084","GO:0070843","GO:1904158","GO:0071630","GO:0006452","GO:0031204","GO:0071374","GO:0001707","GO:1901621","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0045454","GO:0036494","GO:0051259","GO:0046825"]},{"accession":"XP_032242313.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:1903608","GO:0006396"]},{"accession":"XP_048579964.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_048580143.1","go_terms":[]}],"graph":[["XP_001628761.2","XP_001641544.2",0.913],["XP_001628761.2","XP_032220289.1",0.84],["XP_001628761.2","XP_032226358.1",0.943],["XP_001628761.2","XP_032232864.1",0.864],["XP_001628761.2","XP_032242313.2",0.708],["XP_001628761.2","XP_048579964.1",0.921],["XP_001628761.2","XP_048580143.1",0.935],["XP_032242313.2","XP_001641544.2",0.877],["XP_032242313.2","XP_032220289.1",0.653],["XP_032242313.2","XP_032226358.1",0.868],["XP_032242313.2","XP_048579964.1",0.76],["XP_032220289.1","XP_001641544.2",0.79],["XP_032220289.1","XP_032223593.2",0.714],["XP_032220289.1","XP_032232864.1",0.877],["XP_032220289.1","XP_048579964.1",0.749],["XP_032220289.1","XP_048580143.1",0.881],["XP_001641544.2","XP_032232864.1",0.918],["XP_001641544.2","XP_032226358.1",0.84],["XP_001641544.2","XP_048579964.1",0.864],["XP_001641544.2","XP_048580143.1",0.891],["XP_048580143.1","XP_032223593.2",0.714],["XP_048580143.1","XP_032226358.1",0.795],["XP_048580143.1","XP_032232864.1",0.91],["XP_048580143.1","XP_048579964.1",0.885],["XP_048579964.1","XP_032223593.2",0.726],["XP_048579964.1","XP_032232864.1",0.901],["XP_032232864.1","XP_032226358.1",0.51]],"all_go_terms":{"GO:0001825":4,"GO:0016556":4,"GO:0075522":4,"GO:0048026":4,"GO:0034462":4,"GO:0000380":4,"GO:0006446":4,"GO:0048255":4,"GO:1901407":4,"GO:0075525":4,"GO:1902625":4,"GO:0031047":4,"GO:0000381":4,"GO:0006406":4,"GO:0048025":4,"GO:1905663":4,"GO:0002188":4,"GO:0035278":4,"GO:0001731":4,"GO:0006376":4,"GO:0060211":4,"GO:0010610":4,"GO:0045292":4,"GO:1900363":4,"GO:0097010":4,"GO:0006378":4,"GO:1903586":4,"GO:0030260":1,"GO:0015074":1,"GO:0010587":1,"GO:0019076":1,"GO:0019068":1,"GO:0039702":1,"GO:0075713":1,"GO:0039651":1,"GO:0000398":1,"GO:0071031":1,"GO:0046825":2,"GO:0006458":2,"GO:0034975":2,"GO:1900035":2,"GO:0001707":2,"GO:0030433":2,"GO:1905259":1,"GO:1904158":1,"GO:0035719":2,"GO:0036494":2,"GO:0006260":2,"GO:0031204":2,"GO:0070843":2,"GO:0010198":1,"GO:1901621":2,"GO:0071374":2,"GO:0032781":2,"GO:0000002":1,"GO:0097428":2,"GO:0045454":2,"GO:0006452":2,"GO:0006626":2,"GO:0071630":2,"GO:0042787":1,"GO:0090084":2,"GO:0000740":1,"GO:0006924":1,"GO:0006469":2,"GO:0051259":2,"GO:0042026":1,"GO:0070389":2,"GO:0009408":2,"GO:0006986":2,"GO:1903608":1,"GO:0006396":1},"recipe_readded":[]}