{"hash":"1740191514020912849","title":"Cysteine Metabolism and Redox Regulation","description":"The cluster's top GO terms include redox homeostasis, transsulfuration, cysteine-related modifications, and selenocysteine tRNA modification, pointing to a shared emphasis on cysteine chemistry and redox control, with Urmylation as a related post-translational modification pathway. While some terms touch development or cell cycle, the recurring redox/cysteine-oriented processes best unify the proteins.","confidence":"Medium","size":19,"edges":171,"triangles":969,"max_degree":18,"top_function":null,"members":[{"accession":"XP_001635198.3","go_terms":["GO:0032148","GO:0090080","GO:0034605","GO:0071696","GO:0001502","GO:0023019","GO:0043524","GO:0060496","GO:0010966","GO:0014066","GO:0048864","GO:0043049","GO:0007368","GO:0032927","GO:0001823","GO:0030916","GO:0021571","GO:0031069","GO:0032332","GO:0002063","GO:0014843","GO:0045668","GO:0098908","GO:0098909","GO:0008078","GO:0010463","GO:0032781","GO:0050930","GO:0060019","GO:0070349","GO:1901843","GO:0001759","GO:0060664","GO:0060665","GO:0007523","GO:0060661","GO:0007526","GO:0070075","GO:0050674","GO:0050731","GO:0021846","GO:0048505","GO:1903672","GO:0042693","GO:0010002","GO:2000546","GO:0048566","GO:0090263","GO:0060174","GO:0031076","GO:0046326","GO:0030502","GO:2000274","GO:0021703","GO:0043547","GO:0001569","GO:0008406","GO:0051781","GO:0030917","GO:0048807","GO:0046854","GO:0048808","GO:0030878","GO:0048557","GO:0009880","GO:0048702","GO:0055026","GO:0048709","GO:0021543","GO:0046668","GO:0021544","GO:0035019","GO:0070858","GO:0048015","GO:0003338","GO:0030949","GO:0060915","GO:0001974","GO:0008589","GO:0070371","GO:0035909","GO:1901509","GO:0010980","GO:0060681","GO:0021536","GO:0048146","GO:0031016","GO:0060363","GO:0032808","GO:0060615","GO:0060045","GO:0060118","GO:0060595","GO:0021762","GO:1905150","GO:0060591","GO:0060113","GO:0051451","GO:0043616","GO:0031659","GO:0070352","GO:0034394","GO:0042487","GO:0046785","GO:0021798","GO:0060445","GO:0060447","GO:0060449","GO:0060561","GO:2001240","GO:0021795","GO:0010765","GO:0060059","GO:0060425","GO:0050872","GO:0061115","GO:0001656","GO:0001658","GO:0090134","GO:0010838","GO:0042369","GO:1904383","GO:0007399","GO:0021509","GO:0001957","GO:0071338","GO:0050677","GO:0003254","GO:0003198","GO:0045944","GO:0045542","GO:0051145","GO:0070374","GO:0060513","GO:0060510","GO:0000187","GO:0060430","GO:0030324","GO:0060436","GO:0033278","GO:0021572","GO:0070384","GO:0018108","GO:0060667","GO:0042664","GO:0021588","GO:0045445","GO:0021983","GO:0001525","GO:0007275","GO:0021985","GO:0007026","GO:0031532","GO:0046877","GO:0051549","GO:0014709","GO:0060879","GO:0048920","GO:0048538","GO:0061195","GO:0060501","GO:0071157","GO:0035215","GO:0048665","GO:0035231","GO:0060037","GO:0035116","GO:0061033","GO:0036092","GO:0060484","GO:0060129","GO:0060128","GO:0035118","GO:0001839","GO:0042475","GO:0070121","GO:0071542","GO:0003148","GO:0030539","GO:0030538","GO:0048853","GO:0072163","GO:0021940"]},{"accession":"XP_032240406.2","go_terms":[]},{"accession":"XP_001634133.3","go_terms":["GO:0070131","GO:0042254","GO:0042256","GO:1902626","GO:0006355","GO:0000463","GO:0070475","GO:0002127"]},{"accession":"XP_001626174.3","go_terms":["GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_001642050.2","go_terms":["GO:0033158","GO:0043388","GO:0045454","GO:0000122","GO:0098869","GO:1903206","GO:0006662","GO:0080058","GO:0034599","GO:0018401","GO:0055114","GO:0046826","GO:0006351","GO:0016032","GO:1903026","GO:0034976","GO:0034975","GO:0030091","GO:0017004"]},{"accession":"XP_048588282.1","go_terms":["GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_048588283.1","go_terms":["GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_048584921.1","go_terms":["GO:0006450","GO:0006412","GO:0006407"]},{"accession":"XP_048584216.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861","GO:0050852","GO:0006851","GO:0034982","GO:0042776","GO:0035710"]},{"accession":"XP_001630782.1","go_terms":["GO:0097428","GO:0006879","GO:0009399","GO:0016226"]},{"accession":"XP_001628101.1","go_terms":["GO:0006919","GO:0090200","GO:0051402","GO:0071456"]},{"accession":"XP_001633667.2","go_terms":["GO:0006412","GO:0002184"]},{"accession":"XP_001635800.1","go_terms":["GO:0015986","GO:0035786","GO:0021762"]},{"accession":"XP_001638002.1","go_terms":["GO:0006123"]},{"accession":"XP_001641897.2","go_terms":["GO:0032543"]},{"accession":"XP_032232124.2","go_terms":[]},{"accession":"XP_032233325.2","go_terms":["GO:0070966","GO:0071025","GO:0035167","GO:0070481","GO:0000462","GO:0000463","GO:0000466","GO:0006415","GO:0006413","GO:0006412"]},{"accession":"XP_032239209.2","go_terms":[]},{"accession":"XP_032239578.1","go_terms":["GO:0006614","GO:0071353","GO:0042254","GO:0002181","GO:0000027"]}],"graph":[["XP_001634133.3","XP_001626174.3",0.99],["XP_001634133.3","XP_001628101.1",0.988],["XP_001634133.3","XP_001630782.1",0.988],["XP_001634133.3","XP_001633667.2",0.992],["XP_001634133.3","XP_001635198.3",0.961],["XP_001634133.3","XP_001635800.1",0.992],["XP_001634133.3","XP_001638002.1",0.99],["XP_001634133.3","XP_001641897.2",0.991],["XP_001634133.3","XP_001642050.2",0.98],["XP_001634133.3","XP_032232124.2",0.986],["XP_001634133.3","XP_032233325.2",0.989],["XP_001634133.3","XP_032239209.2",0.991],["XP_001634133.3","XP_032239578.1",0.992],["XP_001634133.3","XP_032240406.2",0.991],["XP_001634133.3","XP_048584216.1",0.992],["XP_001634133.3","XP_048584921.1",0.992],["XP_001634133.3","XP_048588282.1",0.972],["XP_001634133.3","XP_048588283.1",0.974],["XP_032239578.1","XP_001626174.3",0.989],["XP_032239578.1","XP_001628101.1",0.988],["XP_032239578.1","XP_001630782.1",0.983],["XP_032239578.1","XP_001633667.2",0.986],["XP_032239578.1","XP_001635198.3",0.991],["XP_032239578.1","XP_001635800.1",0.991],["XP_032239578.1","XP_001638002.1",0.987],["XP_032239578.1","XP_001641897.2",0.99],["XP_032239578.1","XP_001642050.2",0.986],["XP_032239578.1","XP_032232124.2",0.987],["XP_032239578.1","XP_032233325.2",0.983],["XP_032239578.1","XP_032239209.2",0.989],["XP_032239578.1","XP_032240406.2",0.989],["XP_032239578.1","XP_048588282.1",0.981],["XP_032239578.1","XP_048588283.1",0.989],["XP_032239578.1","XP_048584921.1",0.99],["XP_032239578.1","XP_048584216.1",0.992],["XP_001635198.3","XP_001626174.3",0.984],["XP_001635198.3","XP_001628101.1",0.988],["XP_001635198.3","XP_001630782.1",0.983],["XP_001635198.3","XP_001633667.2",0.986],["XP_001635198.3","XP_001641897.2",0.983],["XP_001635198.3","XP_001642050.2",0.99],["XP_001635198.3","XP_001635800.1",0.991],["XP_001635198.3","XP_001638002.1",0.989],["XP_001635198.3","XP_032232124.2",0.989],["XP_001635198.3","XP_032233325.2",0.989],["XP_001635198.3","XP_032239209.2",0.99],["XP_001635198.3","XP_032240406.2",0.983],["XP_001635198.3","XP_048584216.1",0.98],["XP_001635198.3","XP_048584921.1",0.925],["XP_001635198.3","XP_048588282.1",0.984],["XP_001635198.3","XP_048588283.1",0.985],["XP_048588282.1","XP_001626174.3",0.986],["XP_048588282.1","XP_001628101.1",0.986],["XP_048588282.1","XP_001630782.1",0.976],["XP_048588282.1","XP_001633667.2",0.982],["XP_048588282.1","XP_001635800.1",0.988],["XP_048588282.1","XP_001638002.1",0.987],["XP_048588282.1","XP_001641897.2",0.988],["XP_048588282.1","XP_001642050.2",0.982],["XP_048588282.1","XP_032232124.2",0.984],["XP_048588282.1","XP_032233325.2",0.986],["XP_048588282.1","XP_032239209.2",0.985],["XP_048588282.1","XP_032240406.2",0.98],["XP_048588282.1","XP_048584216.1",0.99],["XP_048588282.1","XP_048584921.1",0.987],["XP_048588282.1","XP_048588283.1",0.988],["XP_001635800.1","XP_001626174.3",0.985],["XP_001635800.1","XP_001628101.1",0.986],["XP_001635800.1","XP_001630782.1",0.989],["XP_001635800.1","XP_001633667.2",0.981],["XP_001635800.1","XP_001641897.2",0.99],["XP_001635800.1","XP_001642050.2",0.986],["XP_001635800.1","XP_001638002.1",0.989],["XP_001635800.1","XP_032232124.2",0.988],["XP_001635800.1","XP_032233325.2",0.989],["XP_001635800.1","XP_032239209.2",0.99],["XP_001635800.1","XP_032240406.2",0.989],["XP_001635800.1","XP_048584216.1",0.96],["XP_001635800.1","XP_048584921.1",0.989],["XP_001635800.1","XP_048588283.1",0.987],["XP_001638002.1","XP_001626174.3",0.979],["XP_001638002.1","XP_001628101.1",0.986],["XP_001638002.1","XP_001630782.1",0.973],["XP_001638002.1","XP_001633667.2",0.989],["XP_001638002.1","XP_001641897.2",0.987],["XP_001638002.1","XP_001642050.2",0.977],["XP_001638002.1","XP_032240406.2",0.985],["XP_001638002.1","XP_032239209.2",0.98],["XP_001638002.1","XP_032233325.2",0.984],["XP_001638002.1","XP_032232124.2",0.972],["XP_001638002.1","XP_048588283.1",0.987],["XP_001638002.1","XP_048584921.1",0.982],["XP_001638002.1","XP_048584216.1",0.986],["XP_032240406.2","XP_001626174.3",0.961],["XP_032240406.2","XP_001628101.1",0.987],["XP_032240406.2","XP_001630782.1",0.986],["XP_032240406.2","XP_001633667.2",0.985],["XP_032240406.2","XP_001641897.2",0.983],["XP_032240406.2","XP_001642050.2",0.969],["XP_032240406.2","XP_032232124.2",0.974],["XP_032240406.2","XP_032233325.2",0.989],["XP_032240406.2","XP_032239209.2",0.987],["XP_032240406.2","XP_048588283.1",0.98],["XP_032240406.2","XP_048584921.1",0.986],["XP_032240406.2","XP_048584216.1",0.991],["XP_001626174.3","XP_001641897.2",0.988],["XP_001626174.3","XP_001642050.2",0.986],["XP_001626174.3","XP_001633667.2",0.985],["XP_001626174.3","XP_001630782.1",0.986],["XP_001626174.3","XP_001628101.1",0.987],["XP_001626174.3","XP_032239209.2",0.988],["XP_001626174.3","XP_032233325.2",0.981],["XP_001626174.3","XP_032232124.2",0.98],["XP_001626174.3","XP_048588283.1",0.988],["XP_001626174.3","XP_048584921.1",0.98],["XP_001626174.3","XP_048584216.1",0.992],["XP_032232124.2","XP_001628101.1",0.976],["XP_032232124.2","XP_001630782.1",0.985],["XP_032232124.2","XP_001633667.2",0.988],["XP_032232124.2","XP_001641897.2",0.987],["XP_032232124.2","XP_001642050.2",0.969],["XP_032232124.2","XP_032233325.2",0.985],["XP_032232124.2","XP_032239209.2",0.984],["XP_032232124.2","XP_048584216.1",0.986],["XP_032232124.2","XP_048584921.1",0.987],["XP_032232124.2","XP_048588283.1",0.972],["XP_001633667.2","XP_001628101.1",0.989],["XP_001633667.2","XP_001630782.1",0.984],["XP_001633667.2","XP_001641897.2",0.99],["XP_001633667.2","XP_001642050.2",0.988],["XP_001633667.2","XP_032233325.2",0.989],["XP_001633667.2","XP_032239209.2",0.983],["XP_001633667.2","XP_048584216.1",0.971],["XP_001633667.2","XP_048584921.1",0.988],["XP_001633667.2","XP_048588283.1",0.984],["XP_048584921.1","XP_001628101.1",0.988],["XP_048584921.1","XP_001630782.1",0.984],["XP_048584921.1","XP_001641897.2",0.99],["XP_048584921.1","XP_001642050.2",0.988],["XP_048584921.1","XP_032233325.2",0.988],["XP_048584921.1","XP_032239209.2",0.984],["XP_048584921.1","XP_048584216.1",0.986],["XP_048584921.1","XP_048588283.1",0.977],["XP_048584216.1","XP_001628101.1",0.991],["XP_048584216.1","XP_001630782.1",0.961],["XP_048584216.1","XP_001641897.2",0.992],["XP_048584216.1","XP_001642050.2",0.98],["XP_048584216.1","XP_032233325.2",0.991],["XP_048584216.1","XP_032239209.2",0.992],["XP_048584216.1","XP_048588283.1",0.989],["XP_048588283.1","XP_001628101.1",0.975],["XP_048588283.1","XP_001630782.1",0.982],["XP_048588283.1","XP_001641897.2",0.982],["XP_048588283.1","XP_001642050.2",0.986],["XP_048588283.1","XP_032233325.2",0.989],["XP_048588283.1","XP_032239209.2",0.988],["XP_001642050.2","XP_001628101.1",0.979],["XP_001642050.2","XP_001630782.1",0.985],["XP_001642050.2","XP_001641897.2",0.981],["XP_001642050.2","XP_032239209.2",0.986],["XP_001642050.2","XP_032233325.2",0.978],["XP_032233325.2","XP_001628101.1",0.984],["XP_032233325.2","XP_001630782.1",0.988],["XP_032233325.2","XP_001641897.2",0.989],["XP_032233325.2","XP_032239209.2",0.985],["XP_001641897.2","XP_001628101.1",0.988],["XP_001641897.2","XP_001630782.1",0.988],["XP_001641897.2","XP_032239209.2",0.989],["XP_001628101.1","XP_001630782.1",0.984],["XP_001628101.1","XP_032239209.2",0.987],["XP_032239209.2","XP_001630782.1",0.987]],"all_go_terms":{"GO:0021571":1,"GO:0060037":1,"GO:0031532":1,"GO:0048920":1,"GO:1905150":1,"GO:1901509":1,"GO:0051781":1,"GO:0048538":1,"GO:0010765":1,"GO:0001823":1,"GO:0060449":1,"GO:0001656":1,"GO:0060595":1,"GO:0001525":1,"GO:0000187":1,"GO:0048665":1,"GO:0060425":1,"GO:0031659":1,"GO:0001502":1,"GO:0007399":1,"GO:0071157":1,"GO:0048015":1,"GO:0021798":1,"GO:0090263":1,"GO:0030949":1,"GO:0098909":1,"GO:0070075":1,"GO:0048702":1,"GO:0098908":1,"GO:0003254":1,"GO:0048808":1,"GO:0021544":1,"GO:0060664":1,"GO:0071542":1,"GO:0014843":1,"GO:0030917":1,"GO:0046785":1,"GO:0021985":1,"GO:0070371":1,"GO:0008406":1,"GO:0030878":1,"GO:0030502":1,"GO:0046668":1,"GO:0021572":1,"GO:0021983":1,"GO:0007026":1,"GO:0060129":1,"GO:0060591":1,"GO:0001658":1,"GO:0008078":1,"GO:0042475":1,"GO:0042369":1,"GO:0070349":1,"GO:0042487":1,"GO:0070858":1,"GO:0045668":1,"GO:0007523":1,"GO:0010002":1,"GO:0014066":1,"GO:0003198":1,"GO:0030324":1,"GO:0018108":1,"GO:0001957":1,"GO:0060445":1,"GO:0060661":1,"GO:2000546":1,"GO:0043524":1,"GO:0071338":1,"GO:1904383":1,"GO:0021940":1,"GO:0023019":1,"GO:0001759":1,"GO:0060496":1,"GO:0060681":1,"GO:0032927":1,"GO:0045445":1,"GO:0021703":1,"GO:0060059":1,"GO:0051549":1,"GO:0030539":1,"GO:0033278":1,"GO:0046877":1,"GO:0060045":1,"GO:0070121":1,"GO:0060447":1,"GO:0060915":1,"GO:0035118":1,"GO:0050731":1,"GO:0001569":1,"GO:0021543":1,"GO:0043616":1,"GO:0021795":1,"GO:0061033":1,"GO:2001240":1,"GO:0048566":1,"GO:0034605":1,"GO:0007275":1,"GO:0050677":1,"GO:0060019":1,"GO:0048709":1,"GO:0050872":1,"GO:0034394":1,"GO:0035116":1,"GO:0060484":1,"GO:0090134":1,"GO:0010966":1,"GO:0046854":1,"GO:0035019":1,"GO:0035909":1,"GO:0003338":1,"GO:1901843":1,"GO:0035231":1,"GO:0032148":1,"GO:0043049":1,"GO:0060513":1,"GO:0060879":1,"GO:0050674":1,"GO:0060501":1,"GO:0009880":1,"GO:0021509":1,"GO:0060436":1,"GO:0001839":1,"GO:0055026":1,"GO:0021846":1,"GO:0048505":1,"GO:0060430":1,"GO:0042664":1,"GO:0045944":1,"GO:0030916":1,"GO:0060615":1,"GO:0002063":1,"GO:0071696":1,"GO:0060561":1,"GO:0060510":1,"GO:0048557":1,"GO:0014709":1,"GO:0060667":1,"GO:0035215":1,"GO:0036092":1,"GO:0001974":1,"GO:0072163":1,"GO:0008589":1,"GO:0032808":1,"GO:0021536":1,"GO:0051451":1,"GO:0070352":1,"GO:0061195":1,"GO:0090080":1,"GO:0061115":1,"GO:0051145":1,"GO:0048146":1,"GO:0045542":1,"GO:0060118":1,"GO:0031016":1,"GO:0046326":1,"GO:0031069":1,"GO:0010838":1,"GO:0070384":1,"GO:0003148":1,"GO:2000274":1,"GO:1903672":1,"GO:0032332":1,"GO:0032781":1,"GO:0070374":1,"GO:0060113":1,"GO:0060128":1,"GO:0042693":1,"GO:0060665":1,"GO:0048853":1,"GO:0043547":1,"GO:0048864":1,"GO:0030538":1,"GO:0060363":1,"GO:0021588":1,"GO:0010463":1,"GO:0060174":1,"GO:0050930":1,"GO:0007526":1,"GO:0048807":1,"GO:0010980":1,"GO:0021762":2,"GO:0007368":1,"GO:0031076":1,"GO:0042254":2,"GO:0070131":1,"GO:0002127":1,"GO:0070475":1,"GO:0042256":1,"GO:0006355":1,"GO:1902626":1,"GO:0000463":2,"GO:0018192":3,"GO:0032447":3,"GO:0070329":3,"GO:0006071":3,"GO:0021510":3,"GO:0045454":4,"GO:0000087":3,"GO:0019346":3,"GO:0030855":3,"GO:0035335":3,"GO:0002143":3,"GO:0006777":3,"GO:2000220":3,"GO:0034975":1,"GO:0006351":1,"GO:0046826":1,"GO:0016032":1,"GO:0000122":1,"GO:0018401":1,"GO:0030091":1,"GO:0017004":1,"GO:0034976":1,"GO:0006662":1,"GO:0098869":1,"GO:0034599":1,"GO:0055114":1,"GO:0080058":1,"GO:0033158":1,"GO:1903026":1,"GO:1903206":1,"GO:0043388":1,"GO:0006407":1,"GO:0006412":3,"GO:0006450":1,"GO:1900210":1,"GO:0034982":1,"GO:1990046":1,"GO:0010918":1,"GO:0030433":1,"GO:0007588":1,"GO:0001302":1,"GO:0010876":1,"GO:0034141":1,"GO:2000049":1,"GO:0050852":1,"GO:0070584":1,"GO:0045861":1,"GO:0006851":1,"GO:0000001":1,"GO:1903905":1,"GO:0032623":1,"GO:0052547":1,"GO:0007007":1,"GO:0035710":1,"GO:0022617":1,"GO:0070528":1,"GO:1903044":1,"GO:0090297":1,"GO:0032933":1,"GO:0042776":1,"GO:0045541":1,"GO:1901585":1,"GO:0060355":1,"GO:0032226":1,"GO:0072249":1,"GO:0006879":1,"GO:0097428":1,"GO:0016226":1,"GO:0009399":1,"GO:0006919":1,"GO:0090200":1,"GO:0051402":1,"GO:0071456":1,"GO:0002184":1,"GO:0035786":1,"GO:0015986":1,"GO:0006123":1,"GO:0032543":1,"GO:0070966":1,"GO:0000466":1,"GO:0006413":1,"GO:0071025":1,"GO:0070481":1,"GO:0035167":1,"GO:0006415":1,"GO:0000462":1,"GO:0000027":1,"GO:0002181":1,"GO:0006614":1,"GO:0071353":1},"recipe_readded":[]}