{"hash":"1074550307008241600","title":"Autophagy and mitochondrial stress with innate immune signaling","description":"This cluster combines terms tied to autophagy (autophagosome assembly; regulation of autophagy of mitochondrion), mitochondrial dynamics and stress (membrane potential and fusion regulation; necroptotic regulation), ER protein-folding stress, and innate immune pathways (NF-kappaB signaling, Toll-like receptor signaling, and negative regulation of antiviral defense). Together, these terms point to a cohesive theme where autophagy and mitochondrial stress interfaces modulate innate immune signaling.","confidence":"High","size":3,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_064635335.1","go_terms":[]},{"accession":"XP_064641236.1","go_terms":["GO:0034975","GO:0000045"]},{"accession":"XP_064628812.1","go_terms":["GO:0060544","GO:0000122","GO:0034121","GO:0043066","GO:0000209","GO:0071157","GO:0050689","GO:0030308","GO:0000266","GO:0051898","GO:1903861","GO:0090141","GO:1901028","GO:0033235","GO:0043123","GO:1904215","GO:0006919","GO:1904925","GO:0007257","GO:0051646","GO:0060339","GO:0010637","GO:0031648","GO:0051881","GO:0071360","GO:0071650"]}],"graph":[],"all_go_terms":{"GO:0034975":1,"GO:0000045":1,"GO:0050689":1,"GO:0071157":1,"GO:0051881":1,"GO:0060544":1,"GO:0010637":1,"GO:1904925":1,"GO:0043123":1,"GO:0034121":1,"GO:0033235":1,"GO:0030308":1,"GO:0007257":1,"GO:0051646":1,"GO:0090141":1,"GO:0060339":1,"GO:0071360":1,"GO:0071650":1,"GO:1904215":1,"GO:0006919":1,"GO:0043066":1,"GO:1901028":1,"GO:0000266":1,"GO:0000122":1,"GO:0051898":1,"GO:1903861":1,"GO:0031648":1,"GO:0000209":1},"recipe_readded":["XP_064635442.1","XP_064640467.1","XP_064642515.1","XP_064619883.1","XP_064619298.1","XP_064652323.1","XP_064632247.1","XP_064633074.1","XP_064627407.1","XP_064619124.1","XP_064639969.1","XP_064620743.1","XP_064620559.1","XP_064628680.1","XP_064645921.1"]}