{"hash":"504495769447648291","title":"Cofactor and amino acid biosynthesis with Fe-S assembly","description":"Top GO terms point to multiple biosynthetic pathways (heme precursor protoporphyrinogen IX, biotin, amino acids) along with iron-sulfur cluster assembly and maturation, suggesting the proteins act in cofactor biosynthesis and Fe-S biogenesis rather than a single narrow pathway. The transcription term appears ancillary. This combination supports labeling the cluster as cofactor and amino acid biosynthesis with Fe-S assembly.","confidence":"Medium","size":10,"edges":43,"triangles":105,"max_degree":9,"top_function":"DNA-templated transcription","members":[{"accession":"XP_003961200.2","go_terms":["GO:0019491","GO:0048148","GO:0017000","GO:0009450","GO:0009413","GO:0055129","GO:0009102","GO:0019878","GO:0015995","GO:0006782","GO:0006593","GO:0010121","GO:0009447","GO:0019481","GO:0019483","GO:0042450","GO:0009089"]},{"accession":"XP_003962682.1","go_terms":["GO:0097428","GO:0016226"]},{"accession":"XP_003973777.1","go_terms":["GO:0018339","GO:0006400","GO:1990145","GO:0006777","GO:0009234","GO:0046677","GO:0042426","GO:0009107","GO:0009102","GO:0030488","GO:0006782","GO:0070475","GO:0009249","GO:0009228","GO:0008616","GO:0018189","GO:0019475"]},{"accession":"XP_003973869.2","go_terms":["GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0007219","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0042853","GO:0097053","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_003975367.1","go_terms":["GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0007219","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0042853","GO:0097053","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_003978749.1","go_terms":["GO:0006085","GO:0006099","GO:0006104","GO:0006351","GO:0045892","GO:0051775"]},{"accession":"XP_011603489.2","go_terms":["GO:0030324","GO:0017000","GO:0046677","GO:0042574","GO:0009710","GO:0045150","GO:0006729","GO:0042438","GO:0008207","GO:0055114","GO:0071768","GO:0042619","GO:0031427","GO:0030497","GO:0006355","GO:0008209","GO:0030148","GO:0006710","GO:0042572","GO:0042761","GO:0042376","GO:0006666","GO:0006704","GO:0006703","GO:0002138","GO:0061370","GO:0006706","GO:0030435","GO:0042208","GO:1902321"]},{"accession":"XP_011612366.2","go_terms":["GO:1904482","GO:0034340","GO:0035999","GO:0009113","GO:0046655","GO:0006565","GO:0006564","GO:0006231","GO:0051289","GO:0019264","GO:0017148","GO:0032259"]},{"accession":"XP_003974809.1","go_terms":["GO:0030836","GO:0016311","GO:0032361","GO:0009244","GO:0071318","GO:0097171","GO:0031247","GO:0009103","GO:0033574","GO:0006564","GO:0097755","GO:0006874","GO:0070574","GO:0071577","GO:0006825","GO:0046839","GO:0019373","GO:0046272","GO:0046196","GO:0006470","GO:0046050","GO:0006114"]},{"accession":"XP_029685772.1","go_terms":["GO:0097428","GO:0016226"]}],"graph":[["XP_003978749.1","XP_029685772.1",0.961],["XP_003978749.1","XP_011612366.2",0.959],["XP_003978749.1","XP_003961200.2",0.701],["XP_003978749.1","XP_003962682.1",0.944],["XP_003978749.1","XP_003973777.1",0.937],["XP_003978749.1","XP_003973869.2",0.961],["XP_003978749.1","XP_003974809.1",0.793],["XP_003978749.1","XP_003975367.1",0.971],["XP_003978749.1","XP_011603489.2",0.852],["XP_003961200.2","XP_003962682.1",0.951],["XP_003961200.2","XP_011603489.2",0.611],["XP_003961200.2","XP_003974809.1",0.895],["XP_003961200.2","XP_003975367.1",0.914],["XP_003961200.2","XP_003973777.1",0.97],["XP_003961200.2","XP_003973869.2",0.899],["XP_003961200.2","XP_029685772.1",0.917],["XP_003961200.2","XP_011612366.2",0.931],["XP_029685772.1","XP_011603489.2",0.903],["XP_029685772.1","XP_011612366.2",0.971],["XP_029685772.1","XP_003962682.1",0.968],["XP_029685772.1","XP_003973777.1",0.982],["XP_029685772.1","XP_003973869.2",0.919],["XP_029685772.1","XP_003974809.1",0.635],["XP_029685772.1","XP_003975367.1",0.911],["XP_011612366.2","XP_003962682.1",0.977],["XP_011612366.2","XP_003973777.1",0.955],["XP_011612366.2","XP_003973869.2",0.96],["XP_011612366.2","XP_003974809.1",0.669],["XP_011612366.2","XP_003975367.1",0.938],["XP_003973777.1","XP_003962682.1",0.972],["XP_003973777.1","XP_003973869.2",0.965],["XP_003973777.1","XP_003974809.1",0.628],["XP_003973777.1","XP_003975367.1",0.868],["XP_003973777.1","XP_011603489.2",0.735],["XP_003975367.1","XP_003962682.1",0.942],["XP_003975367.1","XP_003973869.2",0.852],["XP_003975367.1","XP_011603489.2",0.831],["XP_003975367.1","XP_003974809.1",0.788],["XP_003974809.1","XP_003962682.1",0.916],["XP_003974809.1","XP_003973869.2",0.544],["XP_003974809.1","XP_011603489.2",0.81],["XP_003973869.2","XP_003962682.1",0.974],["XP_011603489.2","XP_003962682.1",0.905]],"all_go_terms":{"GO:0015995":1,"GO:0010121":1,"GO:0009447":1,"GO:0019481":1,"GO:0006782":4,"GO:0006593":1,"GO:0019483":1,"GO:0009450":1,"GO:0017000":2,"GO:0019491":1,"GO:0055129":1,"GO:0019878":3,"GO:0009413":1,"GO:0009102":4,"GO:0042450":1,"GO:0009089":1,"GO:0048148":1,"GO:0016226":2,"GO:0097428":2,"GO:0019475":1,"GO:0030488":1,"GO:0009107":1,"GO:0008616":1,"GO:0006777":1,"GO:0009228":1,"GO:0042426":1,"GO:0018339":1,"GO:0009234":1,"GO:0070475":1,"GO:0009249":1,"GO:0018189":1,"GO:1990145":1,"GO:0006400":1,"GO:0046677":2,"GO:0006532":2,"GO:0006523":2,"GO:0055089":2,"GO:0006571":2,"GO:0019550":2,"GO:0009236":2,"GO:0042218":2,"GO:0019551":2,"GO:0019441":2,"GO:0006686":2,"GO:0006351":3,"GO:0006107":2,"GO:0009862":2,"GO:0033585":2,"GO:0015908":2,"GO:0000105":2,"GO:0006533":2,"GO:0009835":2,"GO:0032869":2,"GO:0033512":2,"GO:0007219":2,"GO:0042853":2,"GO:0033362":2,"GO:0019518":2,"GO:0097053":2,"GO:0034276":2,"GO:0006783":2,"GO:0046511":2,"GO:0006085":1,"GO:0051775":1,"GO:0006099":1,"GO:0045892":1,"GO:0006104":1,"GO:0042574":1,"GO:0008207":1,"GO:0030148":1,"GO:0055114":1,"GO:0002138":1,"GO:0006703":1,"GO:0042208":1,"GO:0031427":1,"GO:0042438":1,"GO:0006666":1,"GO:0006729":1,"GO:0042761":1,"GO:0006710":1,"GO:0045150":1,"GO:0061370":1,"GO:1902321":1,"GO:0071768":1,"GO:0042619":1,"GO:0006355":1,"GO:0008209":1,"GO:0042376":1,"GO:0009710":1,"GO:0006706":1,"GO:0030497":1,"GO:0030324":1,"GO:0030435":1,"GO:0006704":1,"GO:0042572":1,"GO:1904482":1,"GO:0006564":2,"GO:0019264":1,"GO:0017148":1,"GO:0006565":1,"GO:0046655":1,"GO:0051289":1,"GO:0035999":1,"GO:0009113":1,"GO:0032259":1,"GO:0006231":1,"GO:0034340":1,"GO:0032361":1,"GO:0046196":1,"GO:0097171":1,"GO:0046050":1,"GO:0006874":1,"GO:0016311":1,"GO:0006825":1,"GO:0019373":1,"GO:0070574":1,"GO:0071318":1,"GO:0030836":1,"GO:0097755":1,"GO:0006114":1,"GO:0006470":1,"GO:0046839":1,"GO:0009244":1,"GO:0031247":1,"GO:0046272":1,"GO:0033574":1,"GO:0009103":1,"GO:0071577":1},"recipe_readded":[]}