{"hash":"2276757552014281615","title":"RNA processing and translation initiation","description":"We note that the cluster's top GO terms cluster around mRNA processing (mRNA modification, alternative splicing, splice site recognition, mRNA stabilization) and translation initiation (formation of translation preinitiation complex, eIF4F complex assembly, translation reinitiation). This suggests proteins in this cluster coordinate RNA maturation with translation initiation and reinitiation, indicating a cohesive RNA metabolism module linking RNA processing to translation control.","confidence":"High","size":13,"edges":76,"triangles":265,"max_degree":12,"top_function":"regulatory ncRNA-mediated gene silencing","members":[{"accession":"XP_003975507.1","go_terms":["GO:0090084","GO:0006458","GO:0006986","GO:0000740","GO:0070843","GO:0042787","GO:0006260","GO:1904158","GO:0006626","GO:1905259","GO:0042026","GO:0030433","GO:0009408","GO:1900035","GO:0035719","GO:0071630","GO:0034975","GO:0010198","GO:0006452","GO:0031204","GO:0071374","GO:0001707","GO:1901621","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0045454","GO:0036494","GO:0051259","GO:0046825"]},{"accession":"XP_003975561.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_011602349.2","go_terms":["GO:0090084","GO:0006458","GO:0006986","GO:0000740","GO:0070843","GO:0042787","GO:0006260","GO:1904158","GO:0006626","GO:1905259","GO:0042026","GO:0030433","GO:0009408","GO:1900035","GO:0035719","GO:0071630","GO:0034975","GO:0010198","GO:0006452","GO:0031204","GO:0071374","GO:0001707","GO:1901621","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0045454","GO:0036494","GO:0051259","GO:0046825"]},{"accession":"XP_011614016.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0003283","GO:0010378","GO:0071947","GO:1990168","GO:0003203","GO:0000122","GO:0043066","GO:1904404","GO:0046832","GO:0071600","GO:0008380","GO:0070536","GO:0006977","GO:0033132","GO:0035523","GO:1900871","GO:0045023","GO:0090526","GO:0036292","GO:0071301","GO:0016567","GO:0003181","GO:0071157"]},{"accession":"XP_029698340.1","go_terms":["GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_003975675.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_029690079.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_011606509.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0003283","GO:0010378","GO:0071947","GO:1990168","GO:0003203","GO:0000122","GO:0043066","GO:1904404","GO:0046832","GO:0071600","GO:0008380","GO:0070536","GO:0006977","GO:0033132","GO:0035523","GO:1900871","GO:0045023","GO:0090526","GO:0036292","GO:0071301","GO:0016567","GO:0003181","GO:0071157"]},{"accession":"XP_011609236.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_011609408.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_029692112.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0003283","GO:0010378","GO:0071947","GO:1990168","GO:0003203","GO:0000122","GO:0043066","GO:1904404","GO:0046832","GO:0071600","GO:0008380","GO:0070536","GO:0006977","GO:0033132","GO:0035523","GO:1900871","GO:0045023","GO:0090526","GO:0036292","GO:0071301","GO:0016567","GO:0003181","GO:0071157"]},{"accession":"XP_003963199.3","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_003970686.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]}],"graph":[["XP_003970686.1","XP_003963199.3",0.837],["XP_003970686.1","XP_003975507.1",0.948],["XP_003970686.1","XP_003975561.1",0.931],["XP_003970686.1","XP_003975675.1",0.903],["XP_003970686.1","XP_011602349.2",0.948],["XP_003970686.1","XP_011606509.2",0.904],["XP_003970686.1","XP_011609236.2",0.978],["XP_003970686.1","XP_011609408.1",0.967],["XP_003970686.1","XP_011614016.1",0.922],["XP_003970686.1","XP_029690079.1",0.912],["XP_003970686.1","XP_029692112.1",0.939],["XP_003970686.1","XP_029698340.1",0.891],["XP_011602349.2","XP_011606509.2",0.93],["XP_011602349.2","XP_011609236.2",0.949],["XP_011602349.2","XP_011609408.1",0.958],["XP_011602349.2","XP_011614016.1",0.91],["XP_011602349.2","XP_029690079.1",0.904],["XP_011602349.2","XP_029692112.1",0.913],["XP_011602349.2","XP_029698340.1",0.921],["XP_011602349.2","XP_003963199.3",0.91],["XP_011602349.2","XP_003975507.1",0.96],["XP_011602349.2","XP_003975561.1",0.893],["XP_011602349.2","XP_003975675.1",0.931],["XP_011609236.2","XP_011606509.2",0.899],["XP_011609236.2","XP_011614016.1",0.907],["XP_011609236.2","XP_011609408.1",0.947],["XP_011609236.2","XP_029698340.1",0.919],["XP_011609236.2","XP_029692112.1",0.889],["XP_011609236.2","XP_029690079.1",0.941],["XP_011609236.2","XP_003963199.3",0.905],["XP_011609236.2","XP_003975507.1",0.958],["XP_011609236.2","XP_003975561.1",0.91],["XP_011609236.2","XP_003975675.1",0.924],["XP_011606509.2","XP_011609408.1",0.937],["XP_011606509.2","XP_011614016.1",0.569],["XP_011606509.2","XP_029690079.1",0.893],["XP_011606509.2","XP_029692112.1",0.705],["XP_011606509.2","XP_029698340.1",0.779],["XP_011606509.2","XP_003963199.3",0.848],["XP_011606509.2","XP_003975507.1",0.947],["XP_011606509.2","XP_003975561.1",0.601],["XP_011606509.2","XP_003975675.1",0.839],["XP_029698340.1","XP_003975507.1",0.902],["XP_029698340.1","XP_003975561.1",0.648],["XP_029698340.1","XP_003975675.1",0.81],["XP_029698340.1","XP_011609408.1",0.95],["XP_029698340.1","XP_011614016.1",0.691],["XP_029698340.1","XP_029690079.1",0.836],["XP_029698340.1","XP_029692112.1",0.776],["XP_029698340.1","XP_003963199.3",0.865],["XP_029690079.1","XP_003975507.1",0.942],["XP_029690079.1","XP_003975561.1",0.837],["XP_029690079.1","XP_003975675.1",0.903],["XP_029690079.1","XP_011609408.1",0.933],["XP_029690079.1","XP_011614016.1",0.877],["XP_029690079.1","XP_029692112.1",0.822],["XP_029690079.1","XP_003963199.3",0.898],["XP_011609408.1","XP_011614016.1",0.945],["XP_011609408.1","XP_029692112.1",0.928],["XP_011609408.1","XP_003963199.3",0.938],["XP_011609408.1","XP_003975507.1",0.942],["XP_011609408.1","XP_003975561.1",0.945],["XP_011609408.1","XP_003975675.1",0.953],["XP_003963199.3","XP_003975507.1",0.918],["XP_003963199.3","XP_003975561.1",0.868],["XP_003963199.3","XP_003975675.1",0.919],["XP_003963199.3","XP_011614016.1",0.839],["XP_003963199.3","XP_029692112.1",0.817],["XP_029692112.1","XP_003975507.1",0.916],["XP_029692112.1","XP_003975561.1",0.564],["XP_029692112.1","XP_003975675.1",0.842],["XP_003975675.1","XP_003975507.1",0.915],["XP_003975675.1","XP_003975561.1",0.813],["XP_003975675.1","XP_011614016.1",0.791],["XP_003975507.1","XP_003975561.1",0.886],["XP_003975507.1","XP_011614016.1",0.909]],"all_go_terms":{"GO:0045454":4,"GO:0070389":4,"GO:0009408":4,"GO:0090084":4,"GO:0000740":2,"GO:0051259":4,"GO:1905259":2,"GO:0071374":4,"GO:0010198":2,"GO:0042026":2,"GO:0006458":4,"GO:0006452":4,"GO:0071630":4,"GO:0097428":4,"GO:0001707":4,"GO:0070843":4,"GO:0042787":2,"GO:0030433":4,"GO:0006626":4,"GO:0046825":4,"GO:0032781":4,"GO:0036494":4,"GO:0006260":4,"GO:1900035":4,"GO:1901621":4,"GO:1904158":2,"GO:0034975":4,"GO:0031204":4,"GO:0035719":4,"GO:0006986":4,"GO:0006469":4,"GO:0035523":3,"GO:0016556":9,"GO:0071157":3,"GO:0001731":9,"GO:0097010":9,"GO:0010378":3,"GO:0036292":3,"GO:0043066":3,"GO:1902625":9,"GO:0046832":3,"GO:0016567":3,"GO:1905663":9,"GO:0003203":3,"GO:0000380":9,"GO:0003181":3,"GO:0070536":3,"GO:0006376":9,"GO:0048255":9,"GO:0071301":3,"GO:1903586":9,"GO:0002188":9,"GO:0071600":3,"GO:0006406":9,"GO:0060211":9,"GO:1901407":9,"GO:1904404":3,"GO:0006977":3,"GO:0000122":3,"GO:0075522":9,"GO:0048026":9,"GO:1900871":3,"GO:1990168":3,"GO:0035278":9,"GO:0010610":9,"GO:0033132":3,"GO:0003283":3,"GO:0045292":9,"GO:0045023":3,"GO:0034462":9,"GO:0001825":9,"GO:0048025":9,"GO:1900363":9,"GO:0008380":3,"GO:0090526":3,"GO:0075525":9,"GO:0031047":9,"GO:0006378":9,"GO:0006446":9,"GO:0071947":3,"GO:0000381":9,"GO:0061158":5,"GO:0071230":5,"GO:0060213":5,"GO:0002931":5,"GO:1900248":5,"GO:1900365":5,"GO:0007310":5,"GO:0032869":5,"GO:0071456":5,"GO:0008069":5,"GO:0045451":5,"GO:0046011":5},"recipe_readded":[]}