{"hash":"811615294820013849","title":"ECM remodeling and cell migration","description":"This cluster is strongly tied to extracellular matrix remodeling and cell movement: hyaluronan metabolism, metallopeptidase activity, and integrin-mediated signaling point to adhesion and ECM remodeling, while extravasation and substrate-dependent cell migration indicate migratory behavior; blood coagulation fits the vascular context, and ubiquitin-protein turnover/proteasome assembly suggest regulation of these processes. Some developmental terms appear, reflecting broader roles in differentiation and regeneration, but the dominant signal is ECM-adhesion and cell migration.","confidence":"High","size":11,"edges":51,"triangles":135,"max_degree":10,"top_function":null,"members":[{"accession":"NP_998540.1","go_terms":["GO:1990126","GO:0045053","GO:0006886","GO:0042147"]},{"accession":"XP_009289819.2","go_terms":["GO:0006821","GO:0002291","GO:0003429","GO:0030212","GO:0070208","GO:0034113","GO:1905050","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:1901202","GO:0015995","GO:0048455","GO:0006511","GO:0043248","GO:0006471","GO:0050908"]},{"accession":"XP_017206632.1","go_terms":["GO:0006821","GO:0002291","GO:0003429","GO:0030212","GO:0070208","GO:0034113","GO:1905050","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:1901202","GO:0015995","GO:0048455","GO:0006511","GO:0043248"]},{"accession":"XP_021332508.1","go_terms":[]},{"accession":"XP_073797918.1","go_terms":["GO:0006471","GO:0006953","GO:0030212","GO:0002291","GO:0003429","GO:0070208","GO:0034113","GO:1905050","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:1901202","GO:0015995","GO:0048455","GO:0006511","GO:0043248","GO:0050908"]},{"accession":"XP_684556.5","go_terms":["GO:0050910","GO:0035677","GO:0010923","GO:0050965","GO:0060117"]},{"accession":"XP_685294.5","go_terms":[]},{"accession":"XP_693183.5","go_terms":["GO:0006953","GO:0030212","GO:0006471","GO:0002291","GO:0003429","GO:0070208","GO:0034113","GO:1905050","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:1901202","GO:0015995","GO:0048455","GO:0006511","GO:0043248","GO:0050908"]},{"accession":"XP_073769893.1","go_terms":["GO:0048313","GO:0006890","GO:0006888","GO:0016185","GO:0043473","GO:0006886","GO:0006896","GO:0036465","GO:0048490","GO:0035646","GO:0051645","GO:0030100","GO:0008344","GO:0048488","GO:0021691"]},{"accession":"XP_009302406.1","go_terms":["GO:0050910","GO:0035677","GO:0010923","GO:0050965","GO:0060117"]},{"accession":"XP_068069177.1","go_terms":["GO:0034446","GO:1905050","GO:0001568","GO:0031532","GO:1901998","GO:1901202","GO:0002291","GO:0003429","GO:0030212","GO:0070208","GO:0034113","GO:0045123","GO:0007229","GO:0007596","GO:0006929","GO:0007161","GO:0031104","GO:0006956","GO:0035987","GO:0015995","GO:0048455","GO:0006511","GO:0043248"]}],"graph":[["XP_021332508.1","NP_998540.1",0.723],["XP_021332508.1","XP_009289819.2",0.784],["XP_021332508.1","XP_009302406.1",0.501],["XP_021332508.1","XP_017206632.1",0.748],["XP_021332508.1","XP_068069177.1",0.685],["XP_021332508.1","XP_073769893.1",0.586],["XP_021332508.1","XP_073797918.1",0.673],["XP_021332508.1","XP_684556.5",0.656],["XP_021332508.1","XP_685294.5",0.747],["XP_021332508.1","XP_693183.5",0.708],["XP_073769893.1","NP_998540.1",0.707],["XP_073769893.1","XP_009289819.2",0.63],["XP_073769893.1","XP_009302406.1",0.573],["XP_073769893.1","XP_017206632.1",0.607],["XP_073769893.1","XP_068069177.1",0.604],["XP_073769893.1","XP_073797918.1",0.618],["XP_073769893.1","XP_684556.5",0.657],["XP_073769893.1","XP_685294.5",0.548],["XP_073769893.1","XP_693183.5",0.544],["XP_073797918.1","NP_998540.1",0.584],["XP_073797918.1","XP_009289819.2",0.712],["XP_073797918.1","XP_017206632.1",0.651],["XP_073797918.1","XP_068069177.1",0.664],["XP_073797918.1","XP_684556.5",0.596],["XP_073797918.1","XP_685294.5",0.662],["XP_073797918.1","XP_693183.5",0.606],["XP_068069177.1","NP_998540.1",0.643],["XP_068069177.1","XP_009289819.2",0.66],["XP_068069177.1","XP_009302406.1",0.52],["XP_068069177.1","XP_017206632.1",0.649],["XP_068069177.1","XP_693183.5",0.631],["XP_068069177.1","XP_684556.5",0.6],["XP_068069177.1","XP_685294.5",0.661],["XP_693183.5","NP_998540.1",0.679],["XP_693183.5","XP_009289819.2",0.754],["XP_693183.5","XP_017206632.1",0.715],["XP_693183.5","XP_684556.5",0.592],["XP_693183.5","XP_685294.5",0.733],["XP_017206632.1","NP_998540.1",0.707],["XP_017206632.1","XP_009289819.2",0.788],["XP_017206632.1","XP_684556.5",0.664],["XP_017206632.1","XP_685294.5",0.755],["NP_998540.1","XP_009289819.2",0.733],["NP_998540.1","XP_009302406.1",0.547],["NP_998540.1","XP_684556.5",0.627],["NP_998540.1","XP_685294.5",0.745],["XP_684556.5","XP_009289819.2",0.688],["XP_684556.5","XP_009302406.1",0.629],["XP_684556.5","XP_685294.5",0.696],["XP_009302406.1","XP_685294.5",0.526],["XP_685294.5","XP_009289819.2",0.795]],"all_go_terms":{"GO:1990126":1,"GO:0042147":1,"GO:0045053":1,"GO:0006886":2,"GO:0006511":5,"GO:1905050":5,"GO:0045123":5,"GO:0050908":3,"GO:0007229":5,"GO:0031104":5,"GO:0035987":5,"GO:0006471":3,"GO:0030212":5,"GO:0006929":5,"GO:0007596":5,"GO:0043248":5,"GO:0048455":5,"GO:0007161":5,"GO:0015995":5,"GO:0002291":5,"GO:1901202":5,"GO:0006821":2,"GO:0034113":5,"GO:0006956":5,"GO:0003429":5,"GO:0070208":5,"GO:0006953":2,"GO:0010923":2,"GO:0050965":2,"GO:0050910":2,"GO:0035677":2,"GO:0060117":2,"GO:0036465":1,"GO:0043473":1,"GO:0048488":1,"GO:0006888":1,"GO:0030100":1,"GO:0016185":1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