{"hash":"2260271314284125075","title":"TLR Signaling and Macrophage Activation","description":"This cluster centers on Toll-like receptor signaling, macrophage activation, and defense against Gram-negative bacteria, with supporting terms for IFN and IL-1\u03b2 production and other immune-related processes; a ubiquitin-proteasome\u2013dependent degradation term suggests dynamic signaling turnover. The brassinosteroid term likely reflects noise from plant pathways.","confidence":"High","size":16,"edges":15,"triangles":5,"max_degree":6,"top_function":null,"members":[{"accession":"XP_068071000.1","go_terms":[]},{"accession":"XP_068077274.1","go_terms":[]},{"accession":"XP_073764981.1","go_terms":[]},{"accession":"XP_073773376.1","go_terms":[]},{"accession":"XP_073776643.1","go_terms":["GO:0006954","GO:0051607","GO:0034138","GO:0042116","GO:1902350","GO:0034154","GO:0034158","GO:0008063","GO:0050729","GO:0045078","GO:0050707","GO:0010080","GO:0006963","GO:0002322","GO:0032722","GO:0043330","GO:0032741","GO:0045087","GO:1900155","GO:0034162","GO:0050830","GO:0034166","GO:0034142","GO:0007352","GO:0002730","GO:0009729","GO:0002755","GO:0002756","GO:0045416","GO:0045356","GO:0045359","GO:0009620","GO:0048833","GO:0009934","GO:0032621","GO:0071225","GO:2000321","GO:0061303","GO:0034134","GO:0030335","GO:0050701","GO:2000813","GO:0002606","GO:0051639","GO:0051638","GO:0032498","GO:0030011","GO:0050829","GO:0044546","GO:0043086","GO:0051770","GO:0006404","GO:0045345","GO:0002374","GO:0006409","GO:0043124","GO:0006407","GO:0032760","GO:0031146","GO:0032611","GO:0002830","GO:0042228","GO:0060335","GO:0035882","GO:0050711","GO:0042345","GO:0031663","GO:0050718","GO:0016045","GO:0032088","GO:1904417","GO:0046827","GO:0032715","GO:0070431","GO:1902745","GO:0032755"]},{"accession":"XP_073777239.1","go_terms":[]},{"accession":"XP_073782531.1","go_terms":[]},{"accession":"XP_073784034.1","go_terms":[]},{"accession":"XP_073789344.1","go_terms":["GO:0032981"]},{"accession":"NP_956936.2","go_terms":["GO:0006450","GO:0006433","GO:0006412"]},{"accession":"NP_957052.1","go_terms":[]},{"accession":"XP_005167243.1","go_terms":[]},{"accession":"NP_957069.1","go_terms":[]},{"accession":"XP_073794122.1","go_terms":["GO:0070970","GO:0042775","GO:0036151","GO:0010143","GO:2001246","GO:0021587","GO:0070236","GO:0035965","GO:0016024","GO:0019432","GO:0002071","GO:0006663","GO:0008611"]},{"accession":"XP_073766807.1","go_terms":["GO:0072756","GO:0035736","GO:0035264","GO:0098789","GO:0006378","GO:0061053"]},{"accession":"XP_073792565.1","go_terms":["GO:0050843","GO:0009236","GO:0017183","GO:0019354","GO:0055114","GO:0000453"]}],"graph":[["XP_068071000.1","NP_957052.1",0.695],["XP_068071000.1","NP_957069.1",0.73],["XP_068071000.1","XP_073764981.1",0.638],["XP_068071000.1","XP_073782531.1",0.559],["XP_073764981.1","NP_957069.1",0.834],["XP_073764981.1","XP_073782531.1",0.582],["XP_073782531.1","NP_957052.1",0.572],["XP_073782531.1","NP_957069.1",0.755],["XP_073782531.1","XP_068077274.1",0.595],["XP_073782531.1","XP_073766807.1",0.647],["XP_073789344.1","NP_957052.1",0.62],["NP_956936.2","XP_005167243.1",0.534],["XP_068077274.1","XP_005167243.1",0.55],["XP_068077274.1","XP_073773376.1",0.648],["NP_957052.1","XP_073773376.1",0.672]],"all_go_terms":{"GO:0031146":1,"GO:0045078":1,"GO:0032715":1,"GO:0002322":1,"GO:0034142":1,"GO:0009729":1,"GO:0050718":1,"GO:0042116":1,"GO:0008063":1,"GO:0050829":1,"GO:1900155":1,"GO:0051770":1,"GO:0002756":1,"GO:0030335":1,"GO:0051607":1,"GO:0043086":1,"GO:0042228":1,"GO:0002755":1,"GO:0002730":1,"GO:0048833":1,"GO:1902350":1,"GO:0045087":1,"GO:0043124":1,"GO:0006407":1,"GO:0034166":1,"GO:0043330":1,"GO:0016045":1,"GO:0006954":1,"GO:0009620":1,"GO:0045345":1,"GO:0050711":1,"GO:0050830":1,"GO:0045416":1,"GO:0045359":1,"GO:0042345":1,"GO:2000813":1,"GO:1904417":1,"GO:0032621":1,"GO:0046827":1,"GO:0060335":1,"GO:0009934":1,"GO:0034134":1,"GO:0051638":1,"GO:0030011":1,"GO:0032760":1,"GO:0032088":1,"GO:0006404":1,"GO:0002830":1,"GO:0045356":1,"GO:0002606":1,"GO:0061303":1,"GO:0050707":1,"GO:0032755":1,"GO:0034158":1,"GO:0034138":1,"GO:2000321":1,"GO:0050729":1,"GO:0044546":1,"GO:0031663":1,"GO:0034154":1,"GO:0032722":1,"GO:0051639":1,"GO:0002374":1,"GO:0034162":1,"GO:0050701":1,"GO:0035882":1,"GO:1902745":1,"GO:0007352":1,"GO:0032498":1,"GO:0006409":1,"GO:0032611":1,"GO:0071225":1,"GO:0010080":1,"GO:0032741":1,"GO:0070431":1,"GO:0006963":1,"GO:0032981":1,"GO:0006412":1,"GO:0006450":1,"GO:0006433":1,"GO:0019432":1,"GO:0021587":1,"GO:2001246":1,"GO:0070236":1,"GO:0035965":1,"GO:0006663":1,"GO:0002071":1,"GO:0008611":1,"GO:0070970":1,"GO:0016024":1,"GO:0010143":1,"GO:0036151":1,"GO:0042775":1,"GO:0035264":1,"GO:0061053":1,"GO:0035736":1,"GO:0072756":1,"GO:0098789":1,"GO:0006378":1,"GO:0009236":1,"GO:0017183":1,"GO:0055114":1,"GO:0019354":1,"GO:0000453":1,"GO:0050843":1},"recipe_readded":["NP_571637.1","NP_878299.1","XP_073783606.1","NP_956980.2","XP_001923843.2","NP_001313494.1","NP_001313451.1","NP_001333205.1","NP_571674.1","XP_009293644.1","NP_001313545.1","XP_073809927.1","NP_878313.2","NP_001314748.1","XP_005156882.1","NP_991162.1","XP_001343650.6","NP_001373599.1","NP_001313370.1","XP_073765267.1"]}