{"hash":"913078376960990203","title":"Mitochondrial Metabolism, Cofactor Synthesis, and Iron Homeostasis","description":"The TOP GO terms point to mitochondrial processes (mitochondrial translation) and core metabolic/cofactor biosynthesis (branched-chain amino acid biosynthesis, molybdopterin cofactor biosynthesis, coenzyme B biosynthesis), along with iron handling (intracellular iron ion homeostasis and response to iron ion starvation). Taken together, these suggest a cluster focused on mitochondrial metabolism and essential cofactor production, with a clear link to iron management. Some terms are broad or obsolete, but the overall theme is coherent enough to label as mitochondrial metabolic and cofactor biosynthesis functions with iron involvement.","confidence":"Medium","size":15,"edges":6,"triangles":1,"max_degree":4,"top_function":null,"members":[{"accession":"XP_032808370.2","go_terms":["GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_032801679.2","go_terms":["GO:0006777","GO:0009688","GO:0006727","GO:0018315","GO:0010118","GO:0045037","GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265"]},{"accession":"XP_032809004.1","go_terms":["GO:0018339","GO:0006400","GO:1990145","GO:0006777","GO:0009234","GO:0046677","GO:0042426","GO:0009107","GO:0009102","GO:0030488","GO:0006782","GO:0070475","GO:0009249","GO:0009228","GO:0008616","GO:0018189","GO:0019475"]},{"accession":"XP_032809459.1","go_terms":["GO:0019878","GO:0006879","GO:0019679","GO:0006099","GO:0050892","GO:0009791","GO:1990641","GO:0009098","GO:0009097","GO:0010040","GO:0032543","GO:0019298"]},{"accession":"XP_032815570.1","go_terms":["GO:0019470","GO:0019877","GO:0042838","GO:0019262","GO:0009089","GO:0046176"]},{"accession":"XP_032817537.1","go_terms":["GO:0006527","GO:0001822","GO:1902269","GO:0098629","GO:0009089","GO:0033387","GO:0008295","GO:0045312"]},{"accession":"XP_032821859.2","go_terms":["GO:0007029","GO:0019876","GO:0009062","GO:0032543","GO:0070681"]},{"accession":"XP_032826346.1","go_terms":["GO:0006527","GO:0001822","GO:1902269","GO:0098629","GO:0009089","GO:0033387","GO:0008295","GO:0045312"]},{"accession":"XP_032826628.1","go_terms":["GO:0010142","GO:0017000","GO:0070317","GO:0006695","GO:0006696","GO:0006084","GO:0009645"]},{"accession":"XP_032830082.2","go_terms":["GO:0019878","GO:0006879","GO:0019679","GO:0006099","GO:0050892","GO:0009791","GO:1990641","GO:0009098","GO:0009097","GO:0010040","GO:0032543","GO:0019298"]},{"accession":"XP_032830249.1","go_terms":["GO:0048702","GO:0035999","GO:0009113","GO:0009257","GO:0001780"]},{"accession":"XP_075911002.1","go_terms":["GO:2001059","GO:0044209","GO:0097171","GO:0009750","GO:0046835","GO:1902777","GO:0006175","GO:0061615","GO:0009744","GO:0010264","GO:0019512","GO:0019303","GO:0006169"]},{"accession":"XP_075922991.1","go_terms":["GO:0019878","GO:0006879","GO:0019679","GO:0006099","GO:0050892","GO:0009791","GO:1990641","GO:0009098","GO:0009097","GO:0010040","GO:0032543","GO:0019298"]},{"accession":"XP_075924609.1","go_terms":["GO:0019478","GO:0046437","GO:0006550","GO:0010817","GO:0009098","GO:0009099","GO:0009097","GO:0046656"]},{"accession":"XP_075926177.1","go_terms":["GO:0006527","GO:0001822","GO:1902269","GO:0098629","GO:0009089","GO:0033387","GO:0008295","GO:0045312"]}],"graph":[["XP_032821859.2","XP_032826628.1",0.583],["XP_032817537.1","XP_032808370.2",0.845],["XP_032817537.1","XP_032826628.1",0.785],["XP_032826346.1","XP_032808370.2",0.86],["XP_032826628.1","XP_032808370.2",0.503],["XP_075926177.1","XP_032808370.2",0.861]],"all_go_terms":{"GO:0006777":3,"GO:0045454":1,"GO:0021510":1,"GO:0032447":1,"GO:0002143":1,"GO:0035335":1,"GO:0018192":1,"GO:2000220":1,"GO:0019346":1,"GO:0070329":1,"GO:0000087":1,"GO:0006071":1,"GO:0030855":1,"GO:0007219":1,"GO:0034516":1,"GO:0043420":1,"GO:0006564":1,"GO:0097053":1,"GO:0042853":1,"GO:0018315":1,"GO:0051591":1,"GO:0046724":1,"GO:0019265":1,"GO:0009436":1,"GO:0051384":1,"GO:0009688":1,"GO:0045037":1,"GO:0042866":1,"GO:0019805":1,"GO:0019448":1,"GO:0019442":1,"GO:0006727":1,"GO:0034354":1,"GO:0010118":1,"GO:0018283":1,"GO:0006546":1,"GO:0070903":1,"GO:0044571":1,"GO:0008615":1,"GO:0019700":1,"GO:0018339":1,"GO:0009107":1,"GO:0046677":1,"GO:0019475":1,"GO:0009234":1,"GO:0042426":1,"GO:0008616":1,"GO:0070475":1,"GO:0009228":1,"GO:0006782":1,"GO:0009249":1,"GO:1990145":1,"GO:0030488":1,"GO:0018189":1,"GO:0009102":1,"GO:0006400":1,"GO:0006879":3,"GO:1990641":3,"GO:0009791":3,"GO:0019679":3,"GO:0019298":3,"GO:0019878":3,"GO:0009097":4,"GO:0009098":4,"GO:0010040":3,"GO:0032543":4,"GO:0006099":3,"GO:0050892":3,"GO:0019470":1,"GO:0046176":1,"GO:0019262":1,"GO:0019877":1,"GO:0009089":4,"GO:0042838":1,"GO:0033387":3,"GO:0098629":3,"GO:1902269":3,"GO:0008295":3,"GO:0001822":3,"GO:0006527":3,"GO:0045312":3,"GO:0019876":1,"GO:0009062":1,"GO:0070681":1,"GO:0007029":1,"GO:0009645":1,"GO:0017000":1,"GO:0006695":1,"GO:0070317":1,"GO:0010142":1,"GO:0006696":1,"GO:0006084":1,"GO:0009113":1,"GO:0001780":1,"GO:0035999":1,"GO:0009257":1,"GO:0048702":1,"GO:0044209":1,"GO:0006175":1,"GO:0009744":1,"GO:2001059":1,"GO:0019303":1,"GO:0046835":1,"GO:1902777":1,"GO:0097171":1,"GO:0061615":1,"GO:0010264":1,"GO:0006169":1,"GO:0019512":1,"GO:0009750":1,"GO:0046656":1,"GO:0009099":1,"GO:0010817":1,"GO:0046437":1,"GO:0006550":1,"GO:0019478":1},"recipe_readded":["XP_075923157.1","XP_075923119.1","XP_032812177.1","XP_075923117.1","XP_075923098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