{"hash":"772572264316667650","title":"Immune signaling and cell adhesion/ECM remodeling","description":"The top GO terms point to immune pathway regulation (notably TLR3 signaling and T cell polarity) alongside modulation of cell\u2013cell and cell\u2013matrix interactions (cadherin regulation, cell adhesion molecule production, ECM disassembly). There are also related processes linked to excretion, aging, and mitochondrial/lipid metabolism (cardiolipin metabolism, mitochondrial membrane potential), suggesting a coordinated role in immune response scaling and tissue interface remodeling rather than a single metabolic pathway. Overall, these proteins seem to participate in immune signaling while also tuning adhesion and ECM dynamics at cellular interfaces.","confidence":"Medium","size":9,"edges":36,"triangles":84,"max_degree":8,"top_function":null,"members":[{"accession":"XP_032807313.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_032802143.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_032814995.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_032820513.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_032832335.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_075924823.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_075926389.1","go_terms":["GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:1903905","GO:0000001","GO:0072249","GO:0032226","GO:0022617","GO:0045541","GO:0070584","GO:0032933","GO:0060355","GO:0007588","GO:0052547","GO:1990046","GO:0034141","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:2000049","GO:1900210","GO:0070528","GO:0045861"]},{"accession":"XP_032820327.1","go_terms":["GO:0034116","GO:0033227","GO:0022617","GO:1901890","GO:0002090","GO:1902992","GO:0090002","GO:1903905","GO:0032092","GO:0044854","GO:0032728","GO:0048643","GO:1901741","GO:0060355","GO:0034141","GO:0007409","GO:0044860","GO:0032226","GO:0071360","GO:2000049","GO:0070528","GO:0045807","GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:0000001","GO:0072249","GO:0045541","GO:0070584","GO:0032933","GO:0007588","GO:0052547","GO:1990046","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:1900210","GO:0045861"]},{"accession":"XP_032823584.1","go_terms":["GO:0034116","GO:0033227","GO:0022617","GO:1901890","GO:0002090","GO:1902992","GO:0090002","GO:1903905","GO:0032092","GO:0044854","GO:0032728","GO:0048643","GO:1901741","GO:0060355","GO:0034141","GO:0007409","GO:0044860","GO:0032226","GO:0071360","GO:2000049","GO:0070528","GO:0045807","GO:0032623","GO:1903044","GO:1901585","GO:0007007","GO:0000001","GO:0072249","GO:0045541","GO:0070584","GO:0032933","GO:0007588","GO:0052547","GO:1990046","GO:0030433","GO:0010876","GO:0010918","GO:0090297","GO:0001302","GO:1900210","GO:0045861"]}],"graph":[["XP_032823584.1","XP_032802143.1",0.953],["XP_032823584.1","XP_032807313.1",0.932],["XP_032823584.1","XP_032814995.1",0.951],["XP_032823584.1","XP_032820327.1",0.908],["XP_032823584.1","XP_032820513.1",0.938],["XP_032823584.1","XP_032832335.1",0.96],["XP_032823584.1","XP_075924823.1",0.956],["XP_032823584.1","XP_075926389.1",0.927],["XP_032820513.1","XP_032802143.1",0.952],["XP_032820513.1","XP_032807313.1",0.96],["XP_032820513.1","XP_032814995.1",0.955],["XP_032820513.1","XP_032820327.1",0.938],["XP_032820513.1","XP_032832335.1",0.936],["XP_032820513.1","XP_075924823.1",0.948],["XP_032820513.1","XP_075926389.1",0.949],["XP_032807313.1","XP_032802143.1",0.959],["XP_032807313.1","XP_032814995.1",0.953],["XP_032807313.1","XP_032832335.1",0.955],["XP_032807313.1","XP_032820327.1",0.914],["XP_032807313.1","XP_075926389.1",0.956],["XP_032807313.1","XP_075924823.1",0.945],["XP_032820327.1","XP_032802143.1",0.957],["XP_032820327.1","XP_032814995.1",0.943],["XP_032820327.1","XP_032832335.1",0.942],["XP_032820327.1","XP_075924823.1",0.948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