{"hash":"34111563493128223","title":"Neuronal Ubiquitin-Proteostasis and RNA Processing","description":"The top terms point to ubiquitin- and sumoylation-related protein modification and turnover (protein sumoylation, ubiquitin-dependent ERAD, deubiquitination), along with regulation of proteolysis and RNA processing/localization (miRNA processing, RNA maintenance). The inclusion of plus-end-directed vesicle transport and cerebellar Purkinje cell layer structure suggests a neuronal context with coordinated protein quality control and RNA metabolism, including trafficking in Purkinje neurons. Overall, this cluster likely represents neuronal ubiquitin-proteostasis coupled to RNA processing pathways.","confidence":"High","size":26,"edges":284,"triangles":1780,"max_degree":25,"top_function":"DNA 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