{"hash":"1877482330124556522","title":"Mitochondrial respiration and cofactor biosynthesis","description":"The top GO terms point to ubiquinone biosynthesis, mitochondrial electron transport (ubiquinol to cytochrome c), and Complex III assembly, all core to mitochondrial energy production and assembly of the respiratory chain. Additional biosynthetic terms (tRNA methylation, biotin, phosphatidylcholine) fit with mitochondrial and cellular metabolism interconnections. Some terms like midbrain development or polycistronic mRNA processing are less directly related and may reflect annotation breadth, but the dominant signal is mitochondrial respiration and cofactor biosynthesis.","confidence":"High","size":25,"edges":280,"triangles":1889,"max_degree":24,"top_function":null,"members":[{"accession":"NP_001232395.1","go_terms":[]},{"accession":"XP_002193913.1","go_terms":["GO:1902600","GO:0006122","GO:0021539","GO:0021860","GO:0021766","GO:0009060","GO:0021854","GO:0030901","GO:0021548","GO:0021680","GO:0021794"]},{"accession":"XP_030126159.4","go_terms":["GO:1902947","GO:0060309","GO:0002542","GO:0031017","GO:0007596","GO:0048771","GO:0055123","GO:0035264","GO:0032496","GO:0006958","GO:0044130","GO:0003050","GO:0045079","GO:0000122","GO:0050720","GO:0031639","GO:0045766","GO:0016055","GO:0001867","GO:0071333","GO:0001878","GO:0070684","GO:0022617","GO:0044537","GO:1900738","GO:0051919","GO:0042127","GO:0032078","GO:0014909","GO:2000097","GO:0097186","GO:0007586","GO:0010756","GO:0070946","GO:0050832","GO:0006953","GO:0050830","GO:0014068","GO:0061113","GO:0031214","GO:0050754","GO:0002523","GO:0009791","GO:0042730","GO:0070947","GO:0045415","GO:0030574","GO:0045944","GO:0030901","GO:1903238","GO:0045752","GO:1903142","GO:0030194","GO:0035750","GO:0045198","GO:0015879","GO:2000474","GO:0032416","GO:2000463","GO:0006470","GO:0045199","GO:0030036","GO:0060088","GO:0050808","GO:1990227","GO:0035023","GO:0007168","GO:0046328","GO:0090557","GO:0035418","GO:0051612","GO:0045186","GO:0090103","GO:0097120","GO:0045075","GO:0098924","GO:0003096","GO:0022007","GO:0035640","GO:0070433","GO:0043004","GO:0090630","GO:0021694","GO:0051835","GO:0060997","GO:0071625","GO:1901206","GO:0008285","GO:0030033","GO:1903361","GO:1903760","GO:0016080","GO:0032782","GO:0071315","GO:0050953","GO:0016358","GO:0051660","GO:1904781","GO:0006887","GO:0007268","GO:0007605","GO:0007266","GO:0070830","GO:2000821","GO:0014047","GO:2000670","GO:0090179","GO:0060292","GO:0019933","GO:0030111","GO:1903028","GO:0035176","GO:0051683","GO:0043113","GO:2000009","GO:0097291","GO:0071896","GO:0006508","GO:1904924","GO:0030163","GO:0035234","GO:0043171"]},{"accession":"XP_002200545.3","go_terms":["GO:0006450","GO:0006399","GO:1900832","GO:1900829"]},{"accession":"NP_001184107.1","go_terms":["GO:1902600","GO:0009060","GO:0006122","GO:0034551"]},{"accession":"NP_001232559.1","go_terms":[]},{"accession":"NP_001232739.1","go_terms":["GO:1904721","GO:1990441","GO:1902065","GO:1902045","GO:0060702","GO:1902236","GO:1902042","GO:1903298","GO:0032469","GO:0051025","GO:0090005","GO:0021681","GO:0021702","GO:0010523"]},{"accession":"NP_001232776.1","go_terms":["GO:1901006"]},{"accession":"XP_002189073.6","go_terms":["GO:0031426","GO:0048507","GO:0010239","GO:0080163","GO:0006744","GO:0043086"]},{"accession":"XP_002195658.7","go_terms":["GO:0036265","GO:0006718","GO:0035572","GO:0035573","GO:0001887","GO:0014075","GO:0002347","GO:0070555","GO:0036068","GO:0018012","GO:0018013","GO:0006972","GO:0042220","GO:0002098","GO:0019505","GO:0035902","GO:0006370","GO:0009877","GO:0046690","GO:1901052","GO:0009236","GO:0017000","GO:0035690","GO:0006656","GO:0019919","GO:0009102","GO:0030488","GO:0016049","GO:0006744","GO:0010189","GO:0016126","GO:0043985","GO:0070476","GO:0000056","GO:0001300","GO:0090398","GO:0030961","GO:0006596","GO:0000154"]},{"accession":"XP_002195743.1","go_terms":["GO:0006933","GO:0006629","GO:0006626","GO:0006814","GO:0030254","GO:0090465","GO:0042777","GO:0042776","GO:0090464","GO:0001525","GO:0001649","GO:0043536","GO:0007035","GO:1902906","GO:0015991","GO:0090463","GO:0044780","GO:0015986","GO:0099132","GO:0071973","GO:0006355","GO:0006353"]},{"accession":"XP_002199796.7","go_terms":["GO:0090502","GO:0001682","GO:0043144","GO:0031425","GO:0016554","GO:0080156","GO:0000961","GO:1905639","GO:0009793","GO:1900865","GO:0042793","GO:0031426","GO:0090617"]},{"accession":"XP_012425274.1","go_terms":[]},{"accession":"XP_030112600.1","go_terms":["GO:0030150"]},{"accession":"XP_030113242.1","go_terms":["GO:0050850","GO:0006915","GO:0006281","GO:0015967","GO:0009154","GO:0044240","GO:0072332","GO:0006694","GO:2000757","GO:0006154","GO:0006351","GO:0031086","GO:0090503","GO:0000290","GO:0000288","GO:0036245","GO:0045292","GO:1901919","GO:0043928"]},{"accession":"XP_030123559.4","go_terms":["GO:0034599","GO:0006515","GO:0007049","GO:0051301","GO:0016558","GO:0061738","GO:0031117","GO:0051260","GO:0030420","GO:2001171","GO:0034214","GO:1903862","GO:0032968","GO:0070842","GO:0001824","GO:0006260","GO:0034551","GO:0070682","GO:0033314","GO:0032979","GO:0051013","GO:0046034","GO:1901800","GO:1990171","GO:0016485","GO:0045899","GO:0030968","GO:0006272","GO:0070987","GO:0043335","GO:0070676","GO:0070370","GO:1903007","GO:0090261","GO:0070914","GO:0061641","GO:0061166","GO:1903715","GO:0006888","GO:0045053","GO:0001319","GO:0035494","GO:0019079","GO:0070414","GO:0097352","GO:0071218","GO:0016562","GO:2000158","GO:0070389","GO:0018279","GO:0006406","GO:0051131","GO:0048219","GO:0030433","GO:1903724","GO:0090296","GO:0072389","GO:0045041","GO:0000733","GO:0070407","GO:0070651","GO:0071712","GO:0035617"]},{"accession":"XP_03012636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