{"hash":"2261625627932513014","title":"Extracellular matrix remodeling and tissue development","description":"The cluster\u2019s top GO terms cluster around remodeling and breakdown of extracellular matrix components (basement membrane disassembly, collagen catabolic process, bone resorption, intramembranous ossification) and developmental processes (lung branching morphogenesis, decidualization). Additional terms like thyroid hormone response and immune-related T cell cytotoxicity appear, but the strongest signal is ECM remodeling coupled with morphogenesis across tissues. This suggests proteins involved in matrix restructuring during development and tissue remodeling rather than a single, narrow function.","confidence":"Medium","size":13,"edges":67,"triangles":193,"max_degree":12,"top_function":null,"members":[{"accession":"XP_027232852.2","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593","GO:2001235","GO:0006508","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418"]},{"accession":"XP_027236296.2","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593","GO:2001235","GO:0006508","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418"]},{"accession":"XP_027236340.1","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593","GO:2001235","GO:0006508"]},{"accession":"XP_069977055.1","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593","GO:2001235","GO:0006508","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418"]},{"accession":"XP_069980920.1","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593"]},{"accession":"XP_069986124.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]},{"accession":"XP_027234221.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]},{"accession":"XP_069974911.1","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593","GO:2001235","GO:0006508","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418"]},{"accession":"XP_069981307.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]},{"accession":"XP_069986125.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]},{"accession":"XP_069976472.1","go_terms":["GO:0045476","GO:0001823","GO:0048469","GO:0008584","GO:0035690","GO:0032496","GO:0050435","GO:0009755","GO:0002003","GO:0002803","GO:0019886","GO:0007586","GO:0006914","GO:0070305","GO:0051591","GO:0042756","GO:0002018","GO:0016540","GO:0002016","GO:0035902","GO:0003406","GO:0009627","GO:0030163","GO:0045493","GO:0006508","GO:0033619","GO:0042985"]},{"accession":"XP_069977053.1","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593","GO:2001235","GO:0006508","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418"]},{"accession":"XP_069977054.1","go_terms":["GO:0051603","GO:0050790","GO:0097067","GO:0001957","GO:0010815","GO:0010813","GO:0030574","GO:2000179","GO:0001913","GO:0060441","GO:0034769","GO:0060448","GO:0046697","GO:0045453","GO:0035593","GO:2001235","GO:0006508","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418"]}],"graph":[["XP_027232852.2","XP_027234221.1",0.703],["XP_027232852.2","XP_027236296.2",0.563],["XP_027232852.2","XP_027236340.1",0.581],["XP_027232852.2","XP_069974911.1",0.514],["XP_027232852.2","XP_069976472.1",0.704],["XP_027232852.2","XP_069977053.1",0.603],["XP_027232852.2","XP_069977054.1",0.734],["XP_027232852.2","XP_069977055.1",0.594],["XP_027232852.2","XP_069980920.1",0.61],["XP_027232852.2","XP_069981307.1",0.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