{"hash":"2298720306681932570","title":"Retroviral life cycle and host interaction","description":"This cluster centers on processes characteristic of retroviral replication and host interaction: viral budding via the ESCRT pathway, virion assembly, viral release, DNA integration, and proviral latency, which together map to the retroviral life cycle. Additional GO terms point to host immune modulation (dendritic cell differentiation, Fc-epsilon receptor signaling) and core RNA-processing activities (snRNP assembly, miRNA catabolic process) that can be co-opted or affected during viral infection. Although there are a few non-viral RNA-processing terms, the prominent viral lifecycle terms provide a coherent overarching theme of virus-host interplay.","confidence":"Medium","size":16,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_003364333.1","go_terms":[]},{"accession":"XP_005598258.2","go_terms":["GO:2001199","GO:0038095"]},{"accession":"XP_014590850.2","go_terms":[]},{"accession":"XP_014593464.3","go_terms":[]},{"accession":"XP_023482763.1","go_terms":[]},{"accession":"XP_070076421.1","go_terms":["GO:0000387","GO:0071031","GO:0010587","GO:0019076","GO:0075713","GO:0019068","GO:0039702","GO:0000398","GO:0030260","GO:0039651","GO:0015074"]},{"accession":"XP_070084866.1","go_terms":["GO:2001199","GO:0038095"]},{"accession":"XP_070087545.1","go_terms":[]},{"accession":"XP_070089689.1","go_terms":[]},{"accession":"XP_070103389.1","go_terms":["GO:0071107","GO:2000828","GO:0040015"]},{"accession":"XP_070104438.1","go_terms":[]},{"accession":"XP_070109894.1","go_terms":[]},{"accession":"XP_070115334.1","go_terms":[]},{"accession":"XP_070118974.1","go_terms":[]},{"accession":"NP_001075330.2","go_terms":["GO:0042347","GO:0033209","GO:0034051","GO:0071222","GO:0042771"]},{"accession":"XP_001505141.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:2001199":2,"GO:0038095":2,"GO:0039702":1,"GO:0000387":1,"GO:0010587":1,"GO:0019076":1,"GO:0075713":1,"GO:0015074":1,"GO:0019068":1,"GO:0030260":1,"GO:0071031":1,"GO:0000398":1,"GO:0039651":1,"GO:0071107":1,"GO:0040015":1,"GO:2000828":1,"GO:0042347":1,"GO:0033209":1,"GO:0034051":1,"GO:0071222":1,"GO:0042771":1},"recipe_readded":["XP_023500971.1","XP_001495775.3","NP_001075335.1","XP_001494518.2","XP_070126446.1","XP_070108867.1"]}