{"hash":"2050160968505042619","title":"Spliceosome Regulation, mRNA Export, and Translation Initiation","description":"The top GO terms cluster around alternative splicing via the spliceosome, splicing regulation and splice-site recognition, plus mRNA export, with a few terms pointing to translation initiation (including viral IRES) and eIF4F assembly. This suggests a cohesive theme of post-transcriptional RNA processing and initiation of translation, with splicing factors and export machinery as core components, and translation-associated elements as related processes.","confidence":"Medium","size":18,"edges":14,"triangles":0,"max_degree":8,"top_function":null,"members":[{"accession":"XP_023510282.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"NP_001137270.2","go_terms":["GO:0046007","GO:0050860","GO:0090314","GO:0035690","GO:0070885","GO:1901216","GO:0071280","GO:1905664","GO:0051260","GO:0032700","GO:0032703","GO:0032689","GO:1901379","GO:1904645","GO:1902951","GO:0098737","GO:0043433","GO:1900272","GO:0050731"]},{"accession":"XP_001489048.3","go_terms":[]},{"accession":"NP_001182517.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_070094010.1","go_terms":[]},{"accession":"XP_001494534.4","go_terms":[]},{"accession":"XP_005609149.1","go_terms":[]},{"accession":"XP_005614785.3","go_terms":[]},{"accession":"XP_023491246.2","go_terms":[]},{"accession":"XP_023505652.1","go_terms":["GO:0000395","GO:0000380"]},{"accession":"XP_023509150.1","go_terms":["GO:0015031","GO:0045956","GO:0045806","GO:0050715"]},{"accession":"XP_014594437.1","go_terms":[]},{"accession":"XP_023510390.2","go_terms":["GO:0042273","GO:0006413"]},{"accession":"XP_070094269.1","go_terms":[]},{"accession":"XP_001500639.4","go_terms":[]},{"accession":"XP_023510362.2","go_terms":["GO:0060195","GO:0033082","GO:0071168","GO:0014834","GO:0021766","GO:0098532","GO:0051567","GO:0097198","GO:0097676","GO:0048387","GO:2000134","GO:0021695","GO:0048298","GO:0034244","GO:0045857","GO:0071314","GO:0071549","GO:0014904","GO:0070314","GO:0034773","GO:0034772","GO:0034771","GO:1903709","GO:0031060","GO:0060669","GO:0051154","GO:0035441","GO:0043433","GO:0036333","GO:0006334","GO:1901674","GO:0080182","GO:0071440","GO:0045944","GO:0097421","GO:0033138","GO:2000616","GO:1903699","GO:1990654","GO:0090309","GO:1900006","GO:0014013","GO:0036166","GO:0045605","GO:0010424","GO:0006469","GO:0048316","GO:0032635","GO:2001040","GO:0003290","GO:0007507","GO:0043516","GO:0035984","GO:0003289","GO:0045128","GO:1904772","GO:0006354","GO:0044648","GO:0006351","GO:0014898"]},{"accession":"XP_023477123.1","go_terms":["GO:0030708","GO:0030713","GO:0006697"]},{"accession":"XP_023489493.1","go_terms":["GO:0032922","GO:0007565","GO:0090190","GO:0070294","GO:0003016"]}],"graph":[["XP_023505652.1","XP_023510362.2",0.519],["XP_014594437.1","XP_023510362.2",0.724],["XP_014594437.1","NP_001137270.2",0.711],["XP_023489493.1","XP_070094010.1",0.515],["XP_023510362.2","XP_005609149.1",0.527],["XP_023510362.2","XP_023491246.2",0.687],["XP_023510362.2","XP_023510282.1",0.794],["XP_023510362.2","XP_070094010.1",0.766],["XP_023510362.2","NP_001182517.1",0.575],["XP_023510362.2","XP_001494534.4",0.59],["XP_001494534.4","XP_023477123.1",0.829],["XP_005609149.1","XP_023477123.1",0.855],["XP_023510282.1","XP_001489048.3",0.769],["XP_023477123.1","XP_070094010.1",0.66]],"all_go_terms":{"GO:0048026":2,"GO:0075525":2,"GO:0075522":2,"GO:0097010":2,"GO:0006376":2,"GO:1900363":2,"GO:0006406":2,"GO:0048025":2,"GO:0031047":2,"GO:1901407":2,"GO:0060211":2,"GO:1903586":2,"GO:0010610":2,"GO:0035278":2,"GO:0000381":2,"GO:0016556":2,"GO:0045292":2,"GO:0006378":2,"GO:1905663":2,"GO:0001731":2,"GO:0002188":2,"GO:0048255":2,"GO:0000380":3,"GO:0001825":2,"GO:1902625":2,"GO:0034462":2,"GO:0006446":2,"GO:0050860":1,"GO:1905664":1,"GO:0032703":1,"GO:0070885":1,"GO:0071280":1,"GO:1902951":1,"GO:0043433":2,"GO:0046007":1,"GO:0050731":1,"GO:0032689":1,"GO:0051260":1,"GO:1900272":1,"GO:0032700":1,"GO:1904645":1,"GO:0035690":1,"GO:0090314":1,"GO:1901216":1,"GO:1901379":1,"GO:0098737":1,"GO:0000395":1,"GO:0045806":1,"GO:0045956":1,"GO:0050715":1,"GO:0015031":1,"GO:0006413":1,"GO:0042273":1,"GO:0071168":1,"GO:0048316":1,"GO:0010424":1,"GO:0033082":1,"GO:0071440":1,"GO:0044648":1,"GO:1903709":1,"GO:1904772":1,"GO:0071314":1,"GO:0034772":1,"GO:0003290":1,"GO:1901674":1,"GO:0043516":1,"GO:0098532":1,"GO:2000134":1,"GO:0021766":1,"GO:0045128":1,"GO:0070314":1,"GO:0034244":1,"GO:0014834":1,"GO:0045944":1,"GO:0080182":1,"GO:0097421":1,"GO:0035441":1,"GO:0090309":1,"GO:0051154":1,"GO:0014904":1,"GO:0048387":1,"GO:0071549":1,"GO:0097198":1,"GO:0032635":1,"GO:0033138":1,"GO:0045605":1,"GO:0003289":1,"GO:1990654":1,"GO:0007507":1,"GO:0034773":1,"GO:0014898":1,"GO:0034771":1,"GO:1903699":1,"GO:0051567":1,"GO:0060669":1,"GO:0006354":1,"GO:0036333":1,"GO:1900006":1,"GO:0048298":1,"GO:0035984":1,"GO:0036166":1,"GO:0021695":1,"GO:0031060":1,"GO:0060195":1,"GO:0097676":1,"GO:0045857":1,"GO:0006469":1,"GO:0006334":1,"GO:0014013":1,"GO:2000616":1,"GO:2001040":1,"GO:0006351":1,"GO:0006697":1,"GO:0030713":1,"GO:0030708":1,"GO:0003016":1,"GO:0007565":1,"GO:0070294":1,"GO:0032922":1,"GO:0090190":1},"recipe_readded":["XP_023487999.2","XP_001493759.1","XP_014587799.1","XP_023475234.1","XP_023492048.1","XP_003362584.1","XP_014592104.2","XP_023492051.1","XP_014592103.3","XP_003365633.2","XP_070125434.1","XP_070121457.1","XP_070080168.1","XP_001504381.1","XP_023482101.1","XP_001492212.1","XP_023473351.2","XP_070080198.1","XP_070120223.1","XP_023493896.1"]}