{"hash":"989848618735208724","title":"Mitochondrial apoptosis and membrane permeabilization","description":"The top GO terms are dominated by mitochondrial events related to apoptosis, including mitochondrial outer membrane permeabilization, and regulation of mitochondrial membrane permeability involved in apoptotic process, plus the generic apoptotic process term. This points to a mitochondria-mediated apoptosis cluster. A few outlier terms (DNA integration, cytochrome b6f complex assembly, placental development, epithelial migration) appear to be noise or cross-annotations rather than core functions of this cluster. Overall, the theme that ties the proteins together is involvement in mitochondrial regulation of apoptosis.","confidence":"Medium","size":6,"edges":5,"triangles":0,"max_degree":5,"top_function":null,"members":[{"accession":"XP_069463621.1","go_terms":[]},{"accession":"XP_069463454.1","go_terms":["GO:0090143","GO:0010190"]},{"accession":"XP_069463392.1","go_terms":[]},{"accession":"XP_069495561.1","go_terms":["GO:0015074","GO:0097345","GO:1903547","GO:0060137","GO:0001893"]},{"accession":"XP_069508967.1","go_terms":[]},{"accession":"XP_069506172.1","go_terms":["GO:0007427","GO:0046011","GO:0006915","GO:0035289","GO:1902108"]}],"graph":[["XP_069463392.1","XP_069463621.1",0.561],["XP_069495561.1","XP_069463621.1",0.664],["XP_069508967.1","XP_069463621.1",0.771],["XP_069463621.1","XP_069463454.1",0.692],["XP_069463621.1","XP_069506172.1",0.606]],"all_go_terms":{"GO:0090143":1,"GO:0010190":1,"GO:0097345":1,"GO:0060137":1,"GO:0001893":1,"GO:0015074":1,"GO:1903547":1,"GO:0007427":1,"GO:0006915":1,"GO:1902108":1,"GO:0035289":1,"GO:0046011":1},"recipe_readded":[]}