{"hash":"2290633619188471428","title":"Sulfur-dependent tRNA modification and redox homeostasis","description":"The top GO terms cluster around sulfur metabolism and RNA modification: transsulfuration, tRNA wobble uridine thiolation, tRNA seleno-modification, URM1/urmylation, and Mo-molybdopterin cofactor biosynthesis\u2014all of which rely on sulfur transfer and redox chemistry. Additional terms like glycerol metabolism and mitotic M phase reflect broader cellular context, while spinal cord development hints at developmental aspects. Taken together, the cluster seems driven by sulfur-assisted RNA modification and related cofactor biosynthesis pathways.","confidence":"High","size":6,"edges":15,"triangles":20,"max_degree":5,"top_function":null,"members":[{"accession":"XP_069488357.1","go_terms":["GO:0000086","GO:0001556","GO:0009794","GO:0034644","GO:0007144","GO:0032467","GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_069501980.1","go_terms":["GO:0000086","GO:0001556","GO:0009794","GO:0034644","GO:0007144","GO:0032467","GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_069501985.1","go_terms":["GO:0000086","GO:0001556","GO:0009794","GO:0034644","GO:0007144","GO:0032467","GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_069467682.1","go_terms":["GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_069486945.1","go_terms":["GO:0033158","GO:0043388","GO:0045454","GO:0000122","GO:0098869","GO:1903206","GO:0006662","GO:0080058","GO:0034599","GO:0018401","GO:0055114","GO:0046826","GO:0006351","GO:0016032","GO:1903026","GO:0034976","GO:0034975","GO:0030091"]},{"accession":"XP_069507404.1","go_terms":["GO:0000722","GO:0009244","GO:0006351","GO:0070525","GO:0006468"]}],"graph":[["XP_069501980.1","XP_069486945.1",0.979],["XP_069501980.1","XP_069488357.1",0.974],["XP_069501980.1","XP_069501985.1",0.86],["XP_069501980.1","XP_069507404.1",0.979],["XP_069501980.1","XP_069467682.1",0.982],["XP_069488357.1","XP_069486945.1",0.859],["XP_069488357.1","XP_069507404.1",0.963],["XP_069488357.1","XP_069501985.1",0.922],["XP_069488357.1","XP_069467682.1",0.986],["XP_069501985.1","XP_069486945.1",0.856],["XP_069501985.1","XP_069507404.1",0.963],["XP_069501985.1","XP_069467682.1",0.982],["XP_069467682.1","XP_069486945.1",0.961],["XP_069467682.1","XP_069507404.1",0.961],["XP_069507404.1","XP_069486945.1",0.727]],"all_go_terms":{"GO:0009794":3,"GO:0006071":4,"GO:0045454":5,"GO:0019346":4,"GO:0032447":4,"GO:0007144":3,"GO:0006777":4,"GO:0000086":3,"GO:0001556":3,"GO:0021510":4,"GO:0035335":4,"GO:0070329":4,"GO:0034644":3,"GO:0002143":4,"GO:0032467":3,"GO:0000087":4,"GO:2000220":4,"GO:0018192":4,"GO:0030855":4,"GO:0043388":1,"GO:0006351":2,"GO:0034976":1,"GO:0034975":1,"GO:0098869":1,"GO:0006662":1,"GO:0016032":1,"GO:0030091":1,"GO:0018401":1,"GO:0080058":1,"GO:1903206":1,"GO:0055114":1,"GO:1903026":1,"GO:0000122":1,"GO:0046826":1,"GO:0034599":1,"GO:0033158":1,"GO:0000722":1,"GO:0070525":1,"GO:0006468":1,"GO:0009244":1},"recipe_readded":[]}