{"hash":"306665609345797987","title":"Central carbon metabolism and energy production","description":"The cluster shows strong representation of glycolysis, the TCA cycle, acetyl-CoA formation, gluconeogenesis, and amino-acid catabolism feeding into energy pathways, with associated fatty acid biosynthesis\u2014together defining central carbon metabolism and energy generation. Minor sodium transport is present but does not define the cluster.","confidence":"High","size":16,"edges":119,"triangles":546,"max_degree":15,"top_function":"DNA-templated transcription","members":[{"accession":"XP_071811169.1","go_terms":["GO:0043617","GO:0006086","GO:0033512","GO:0006213","GO:0006099","GO:0006096","GO:0000002","GO:0006103","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006094"]},{"accession":"XP_071812109.1","go_terms":["GO:0006545","GO:0006567","GO:0006570","GO:0006569","GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265","GO:0009243","GO:0017000","GO:0009246","GO:0009245","GO:0071555","GO:0046677","GO:0009103"]},{"accession":"XP_071815725.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0033320","GO:0009258","GO:0006730","GO:0009245","GO:0071951","GO:0046677","GO:0006189","GO:0006413","GO:0009103"]},{"accession":"XP_071815755.1","go_terms":["GO:0072756","GO:0009228","GO:0072747","GO:0046166","GO:0061732","GO:0006098","GO:0006096","GO:0055114","GO:0052865","GO:0005999","GO:0040008","GO:0010510","GO:0006006","GO:0016114","GO:0061034","GO:0006099"]},{"accession":"XP_071818533.1","go_terms":["GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0007219","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0042853","GO:0097053","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_071818608.1","go_terms":["GO:0072756","GO:0009228","GO:0072747","GO:0046166","GO:0061732","GO:0006098","GO:0006096","GO:0055114","GO:0052865","GO:0005999","GO:0040008","GO:0010510","GO:0006006","GO:0016114","GO:0061034","GO:0006099"]},{"accession":"XP_071820231.1","go_terms":["GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265","GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362","GO:0009243","GO:0017000","GO:0009246","GO:0009245","GO:0071555","GO:0046677","GO:0009103"]},{"accession":"XP_071825386.1","go_terms":["GO:0006635","GO:0042372","GO:0017000","GO:0010124","GO:0009234","GO:0006574"]},{"accession":"XP_071830426.1","go_terms":["GO:0043617","GO:0006086","GO:0033512","GO:0006213","GO:0006099","GO:0006096","GO:0000002","GO:0006103","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006094"]},{"accession":"XP_071835224.1","go_terms":["GO:0043617","GO:0006086","GO:0000002","GO:0006099","GO:0006103","GO:0033512","GO:0006096","GO:0006814","GO:2001295","GO:0042759","GO:0006552","GO:0006213","GO:0006094"]},{"accession":"XP_071838845.1","go_terms":["GO:0044268","GO:0019552","GO:0042759","GO:2001295","GO:0006633"]},{"accession":"XP_071839324.1","go_terms":["GO:0006189","GO:0044791","GO:0019074","GO:0031999","GO:0006552","GO:0044268","GO:0006094","GO:0042759","GO:0006090","GO:0045717","GO:2001295","GO:0007494","GO:0044344","GO:0045984","GO:0001889","GO:0042594","GO:0043200","GO:0014075","GO:0032094","GO:0071377","GO:0044205","GO:0006541","GO:0006526","GO:0070365","GO:0055081","GO:0071548","GO:1903718","GO:0071320","GO:0071400","GO:0006207","GO:0070409","GO:0060416","GO:0019240","GO:0033512","GO:0006814","GO:0006099","GO:0006096","GO:0006086","GO:0006213","GO:0071555","GO:0008360","GO:0009252","GO:0019878","GO:0018410","GO:0051516","GO:0009432","GO:0032958","GO:0006412"]},{"accession":"XP_071839714.1","go_terms":["GO:0051384","GO:0018283","GO:0034354","GO:0009436","GO:0043420","GO:0019442","GO:0007219","GO:0019448","GO:0006546","GO:0042866","GO:0006564","GO:0044571","GO:0019700","GO:0046724","GO:0070903","GO:0008615","GO:0019805","GO:0042853","GO:0097053","GO:0034516","GO:0051591","GO:0019265","GO:0034276","GO:0033512","GO:0042218","GO:0032869","GO:0000105","GO:0009102","GO:0019878","GO:0006783","GO:0009862","GO:0019550","GO:0009236","GO:0006686","GO:0033585","GO:0015908","GO:0019441","GO:0006533","GO:0055089","GO:0006571","GO:0009835","GO:0019518","GO:0006523","GO:0006107","GO:0019551","GO:0006351","GO:0006532","GO:0006782","GO:0046511","GO:0033362"]},{"accession":"XP_071843774.1","go_terms":["GO:0036111","GO:0032385","GO:0036112","GO:0008209","GO:0032150","GO:0060009","GO:1901373","GO:0006635","GO:0019619","GO:0001889","GO:0042594","GO:0060612","GO:0046952","GO:0014070","GO:0046951","GO:0072229","GO:0051260","GO:1901029","GO:0046356","GO:0030435","GO:0010111","GO:0008203","GO:0007420","GO:0009725","GO:0006550","GO:0042619","GO:1902860","GO:1902109","GO:0018909"]},{"accession":"XP_071848859.1","go_terms":["GO:0080093","GO:0048569","GO:0007584","GO:0006734","GO:0006099","GO:0051591","GO:0043627","GO:0006097","GO:0006096","GO:0001666","GO:0042542","GO:0042493","GO:0006107","GO:0009749","GO:0043065","GO:0055114","GO:0019244","GO:0006108"]},{"accession":"XP_071854484.1","go_terms":["GO:0042391","GO:0051068","GO:0042853","GO:0061732","GO:0006099","GO:0050787","GO:0046653","GO:0048240","GO:0009106","GO:0030488","GO:0007369","GO:0006096","GO:0006103","GO:0045454","GO:0070899","GO:0007568","GO:0006120","GO:0010510","GO:0006554","GO:0030851","GO:0042135","GO:0034720","GO:0051412","GO:0035563","GO:0010044","GO:0001701","GO:0043046","GO:0098869","GO:0010725","GO:0060992","GO:2000179","GO:1990138","GO:0046886","GO:0014063","GO:0045793","GO:0071320","GO:0045654","GO:0009061","GO:0006121","GO:0042493","GO:0009435","GO:0021983","GO:0032496","GO:0021987","GO:0042420","GO:0000380","GO:0045648","GO:0019563","GO:0016575","GO:2000648","GO:0009228","GO:0045471","GO:0046098","GO:0051572","GO:0051573","GO:0002098","GO:0010269","GO:0042551","GO:0045964","GO:0006105"]}],"graph":[["XP_071811169.1","XP_071812109.1",0.985],["XP_071811169.1","XP_071815725.1",0.966],["XP_071811169.1","XP_071815755.1",0.977],["XP_071811169.1","XP_071818533.1",0.983],["XP_071811169.1","XP_071818608.1",0.955],["XP_071811169.1","XP_071820231.1",0.983],["XP_071811169.1","XP_071825386.1",0.975],["XP_071811169.1","XP_071830426.1",0.951],["XP_071811169.1","XP_071835224.1",0.746],["XP_071811169.1","XP_071838845.1",0.972],["XP_071811169.1","XP_071839324.1",0.992],["XP_071811169.1","XP_071839714.1",0.972],["XP_071811169.1","XP_071843774.1",0.976],["XP_071811169.1","XP_071848859.1",0.96],["XP_071811169.1","XP_071854484.1",0.985],["XP_071825386.1","XP_071812109.1",0.984],["XP_071825386.1","XP_071815725.1",0.984],["XP_071825386.1","XP_071815755.1",0.982],["XP_071825386.1","XP_071818533.1",0.986],["XP_071825386.1","XP_071818608.1",0.988],["XP_071825386.1","XP_071820231.1",0.988],["XP_071825386.1","XP_071830426.1",0.989],["XP_071825386.1","XP_071835224.1",0.989],["XP_071825386.1","XP_071838845.1",0.991],["XP_071825386.1","XP_071839324.1",0.983],["XP_071825386.1","XP_071839714.1",0.975],["XP_071825386.1","XP_071843774.1",0.958],["XP_071825386.1","XP_071848859.1",0.981],["XP_071825386.1","XP_071854484.1",0.975],["XP_071835224.1","XP_071812109.1",0.979],["XP_071835224.1","XP_071815725.1",0.968],["XP_071835224.1","XP_071815755.1",0.896],["XP_071835224.1","XP_071818533.1",0.983],["XP_071835224.1","XP_071818608.1",0.836],["XP_071835224.1","XP_071820231.1",0.972],["XP_071835224.1","XP_071830426.1",0.674],["XP_071835224.1","XP_071838845.1",0.891],["XP_071835224.1","XP_071839324.1",0.725],["XP_071835224.1","XP_071839714.1",0.947],["XP_071835224.1","XP_071854484.1",0.977],["XP_071835224.1","XP_071843774.1",0.975],["XP_071838845.1","XP_071812109.1",0.987],["XP_071838845.1","XP_071815725.1",0.979],["XP_071838845.1","XP_071815755.1",0.989],["XP_071838845.1","XP_071818533.1",0.985],["XP_071838845.1","XP_071818608.1",0.989],["XP_071838845.1","XP_071820231.1",0.981],["XP_071838845.1","XP_071830426.1",0.959],["XP_071838845.1","XP_071839324.1",0.989],["XP_071838845.1","XP_071839714.1",0.984],["XP_071838845.1","XP_071843774.1",0.976],["XP_071838845.1","XP_071848859.1",0.982],["XP_071838845.1","XP_071854484.1",0.976],["XP_071839324.1","XP_071812109.1",0.989],["XP_071839324.1","XP_071815725.1",0.976],["XP_071839324.1","XP_071815755.1",0.959],["XP_071839324.1","XP_071818533.1",0.88],["XP_071839324.1","XP_071818608.1",0.981],["XP_071839324.1","XP_071820231.1",0.975],["XP_071839324.1","XP_071830426.1",0.979],["XP_071839324.1","XP_071839714.1",0.97],["XP_071839324.1","XP_071843774.1",0.978],["XP_071839324.1","XP_071848859.1",0.929],["XP_071839324.1","XP_071854484.1",0.981],["XP_071843774.1","XP_071812109.1",0.966],["XP_071843774.1","XP_071815725.1",0.972],["XP_071843774.1","XP_071815755.1",0.988],["XP_071843774.1","XP_071818533.1",0.98],["XP_071843774.1","XP_071818608.1",0.99],["XP_071843774.1","XP_071820231.1",0.966],["XP_071843774.1","XP_071830426.1",0.978],["XP_071843774.1","XP_071839714.1",0.95],["XP_071843774.1","XP_071848859.1",0.987],["XP_071843774.1","XP_071854484.1",0.949],["XP_071854484.1","XP_071812109.1",0.984],["XP_071854484.1","XP_071815725.1",0.988],["XP_071854484.1","XP_071815755.1",0.991],["XP_071854484.1","XP_071818533.1",0.992],["XP_071854484.1","XP_071818608.1",0.98],["XP_071854484.1","XP_071820231.1",0.964],["XP_071854484.1","XP_071830426.1",0.975],["XP_071854484.1","XP_071839714.1",0.986],["XP_071854484.1","XP_071848859.1",0.991],["XP_071818533.1","XP_071812109.1",0.992],["XP_071818533.1","XP_071815725.1",0.978],["XP_071818533.1","XP_071815755.1",0.987],["XP_071818533.1","XP_071818608.1",0.983],["XP_071818533.1","XP_071820231.1",0.989],["XP_071818533.1","XP_071830426.1",0.986],["XP_071818533.1","XP_071839714.1",0.977],["XP_071818533.1","XP_071848859.1",0.899],["XP_071815755.1","XP_071812109.1",0.982],["XP_071815755.1","XP_071820231.1",0.986],["XP_071815755.1","XP_071818608.1",0.975],["XP_071815755.1","XP_071815725.1",0.986],["XP_071815755.1","XP_071839714.1",0.987],["XP_071815755.1","XP_071830426.1",0.935],["XP_071815755.1","XP_071848859.1",0.927],["XP_071818608.1","XP_071812109.1",0.98],["XP_071818608.1","XP_071815725.1",0.989],["XP_071818608.1","XP_071820231.1",0.99],["XP_071818608.1","XP_071830426.1",0.95],["XP_071818608.1","XP_071839714.1",0.978],["XP_071818608.1","XP_071848859.1",0.951],["XP_071848859.1","XP_071812109.1",0.99],["XP_071848859.1","XP_071815725.1",0.986],["XP_071848859.1","XP_071820231.1",0.988],["XP_071848859.1","XP_071830426.1",0.877],["XP_071848859.1","XP_071839714.1",0.976],["XP_071815725.1","XP_071812109.1",0.951],["XP_071815725.1","XP_071820231.1",0.952],["XP_071815725.1","XP_071839714.1",0.98],["XP_071815725.1","XP_071830426.1",0.929],["XP_071830426.1","XP_071812109.1",0.985],["XP_071830426.1","XP_071820231.1",0.986],["XP_071830426.1","XP_071839714.1",0.966],["XP_071820231.1","XP_071812109.1",0.981],["XP_071820231.1","XP_071839714.1",0.971],["XP_071839714.1","XP_071812109.1",0.973]],"all_go_terms":{"GO:0033512":7,"GO:0006099":8,"GO:0006094":4,"GO:0042759":5,"GO:0006086":4,"GO:0006096":8,"GO:0006814":4,"GO:0006552":4,"GO:2001295":5,"GO:0000002":3,"GO:0006213":4,"GO:0043617":3,"GO:0006103":4,"GO:0019265":3,"GO:0071555":3,"GO:0019442":3,"GO:0008615":3,"GO:0019805":3,"GO:0017000":4,"GO:0009246":2,"GO:0046724":3,"GO:0018283":3,"GO:0019700":3,"GO:0009436":3,"GO:0070903":3,"GO:0006569":1,"GO:0009103":3,"GO:0042853":5,"GO:0046677":3,"GO:0051384":3,"GO:0006546":3,"GO:0009243":2,"GO:0007219":4,"GO:0044571":3,"GO:0042866":3,"GO:0043420":3,"GO:0034516":3,"GO:0097053":4,"GO:0009245":3,"GO:0006545":1,"GO:0006564":3,"GO:0051591":4,"GO:0006570":1,"GO:0019448":3,"GO:0006567":1,"GO:0034354":3,"GO:0009234":2,"GO:0071951":1,"GO:0006413":1,"GO:0042372":2,"GO:0009258":1,"GO:0033320":1,"GO:0006730":1,"GO:0006189":2,"GO:0006635":3,"GO:0010124":2,"GO:0009228":3,"GO:0010510":3,"GO:0061732":3,"GO:0052865":2,"GO:0040008":2,"GO:0006006":2,"GO:0046166":2,"GO:0072756":2,"GO:0006098":2,"GO:0055114":3,"GO:0061034":2,"GO:0072747":2,"GO:0005999":2,"GO:0016114":2,"GO:0009236":3,"GO:0009862":3,"GO:0006523":3,"GO:0006351":3,"GO:0006783":3,"GO:0006107":4,"GO:0046511":3,"GO:0019518":3,"GO:0009102":3,"GO:0006533":3,"GO:0000105":3,"GO:0055089":3,"GO:0019550":3,"GO:0006532":3,"GO:0033585":3,"GO:0009835":3,"GO:0006571":3,"GO:0034276":3,"GO:0006782":3,"GO:0006686":3,"GO:0019878":4,"GO:0019551":3,"GO:0019441":3,"GO:0033362":3,"GO:0032869":3,"GO:0042218":3,"GO:0015908":3,"GO:0006574":1,"GO:0019552":1,"GO:0006633":1,"GO:0044268":2,"GO:0042594":2,"GO:0071548":1,"GO:0044205":1,"GO:0001889":2,"GO:0009432":1,"GO:0031999":1,"GO:1903718":1,"GO:0008360":1,"GO:0006412":1,"GO:0071377":1,"GO:0070409":1,"GO:0032958":1,"GO:0007494":1,"GO:0014075":1,"GO:0070365":1,"GO:0044791":1,"GO:0019240":1,"GO:0032094":1,"GO:0045717":1,"GO:0006526":1,"GO:0009252":1,"GO:0044344":1,"GO:0060416":1,"GO:0019074":1,"GO:0055081":1,"GO:0006207":1,"GO:0051516":1,"GO:0045984":1,"GO:0071320":2,"GO:0018410":1,"GO:0071400":1,"GO:0006090":1,"GO:0006541":1,"GO:0043200":1,"GO:0060612":1,"GO:0032385":1,"GO:0030435":1,"GO:0046356":1,"GO:0036112":1,"GO:1901029":1,"GO:1902860":1,"GO:0010111":1,"GO:0072229":1,"GO:0051260":1,"GO:0008203":1,"GO:0009725":1,"GO:0019619":1,"GO:0036111":1,"GO:0008209":1,"GO:0046952":1,"GO:1901373":1,"GO:1902109":1,"GO:0060009":1,"GO:0007420":1,"GO:0046951":1,"GO:0006550":1,"GO:0032150":1,"GO:0042619":1,"GO:0014070":1,"GO:0018909":1,"GO:0042542":1,"GO:0048569":1,"GO:0006097":1,"GO:0080093":1,"GO:0001666":1,"GO:0006108":1,"GO:0009749":1,"GO:0007584":1,"GO:0043065":1,"GO:0043627":1,"GO:0006734":1,"GO:0019244":1,"GO:0042493":2,"GO:0007369":1,"GO:0010044":1,"GO:0019563":1,"GO:0010269":1,"GO:0006121":1,"GO:0035563":1,"GO:0046098":1,"GO:0042420":1,"GO:0046886":1,"GO:0051412":1,"GO:0009061":1,"GO:0042551":1,"GO:0021983":1,"GO:0001701":1,"GO:0014063":1,"GO:0006554":1,"GO:0045654":1,"GO:0016575":1,"GO:0034720":1,"GO:0060992":1,"GO:0045471":1,"GO:0006105":1,"GO:0043046":1,"GO:0030488":1,"GO:1990138":1,"GO:0042391":1,"GO:0051572":1,"GO:0042135":1,"GO:0002098":1,"GO:0009106":1,"GO:0051573":1,"GO:0007568":1,"GO:0010725":1,"GO:0000380":1,"GO:0051068":1,"GO:0045793":1,"GO:0070899":1,"GO:0045964":1,"GO:0032496":1,"GO:2000648":1,"GO:0050787":1,"GO:0021987":1,"GO:2000179":1,"GO:0009435":1,"GO:0006120":1,"GO:0046653":1,"GO:0045454":1,"GO:0098869":1,"GO:0045648":1,"GO:0030851":1,"GO:0048240":1},"recipe_readded":[]}