{"hash":"167264880826721630","title":"Retroviral DNA integration and latency","description":"The cluster is dominated by GO terms tied to retroviral life-cycle steps: DNA replication/recombination, DNA integration, RNA-templated DNA biosynthesis (reverse transcription), and establishment of integrated proviral latency, plus viral penetration into the host nucleus. These collectively point to retroviral genome integration and latency as the central theme, with some related virus-host interaction signals (and related intracellular symbiont entries) contributing context. ","confidence":"High","size":13,"edges":76,"triangles":265,"max_degree":12,"top_function":"DNA recombination","members":[{"accession":"XP_071815015.1","go_terms":["GO:0006310","GO:0010212","GO:0006281","GO:0009432","GO:0000722","GO:2000269","GO:0071480","GO:0009636","GO:0051106","GO:0090267","GO:0036297","GO:0000732","GO:0007294","GO:0007066","GO:0007533","GO:0007141","GO:0010165","GO:0001541","GO:1990918","GO:0009949","GO:0051260","GO:0007129","GO:0000707","GO:0001556","GO:1990426","GO:0072757","GO:0000709","GO:0072719","GO:0010569","GO:0072711","GO:0007286","GO:0042148","GO:0007131","GO:0007130","GO:1904631","GO:0090656","GO:0009951","GO:0045003","GO:0006268","GO:0001832","GO:0030491","GO:0042493","GO:0030717","GO:1990414","GO:0001932","GO:0071140","GO:0007127","GO:0006260","GO:0032508","GO:0000730","GO:0006412","GO:0071897","GO:0006276"]},{"accession":"XP_071832662.1","go_terms":["GO:0006310","GO:0010212","GO:0006281","GO:0009432","GO:0000722","GO:2000269","GO:0071480","GO:0009636","GO:0051106","GO:0090267","GO:0036297","GO:0000732","GO:0007294","GO:0007066","GO:0007533","GO:0007141","GO:0010165","GO:0001541","GO:1990918","GO:0009949","GO:0051260","GO:0007129","GO:0000707","GO:0001556","GO:1990426","GO:0072757","GO:0000709","GO:0072719","GO:0010569","GO:0072711","GO:0007286","GO:0042148","GO:0007131","GO:0007130","GO:1904631","GO:0090656","GO:0009951","GO:0045003","GO:0006268","GO:0001832","GO:0030491","GO:0042493","GO:0030717","GO:1990414","GO:0001932","GO:0071140","GO:0007127","GO:0006260","GO:0032508","GO:0000730","GO:0006412","GO:0071897","GO:0006276"]},{"accession":"XP_071821858.1","go_terms":["GO:0035229","GO:0044598","GO:0071799","GO:0001894","GO:0009414","GO:0060135","GO:0042572","GO:0042574","GO:0006750","GO:0019853","GO:0071395","GO:0044597","GO:0071805","GO:0042840","GO:0003091","GO:0042843","GO:0042448","GO:0031098","GO:0043066","GO:0042821","GO:0061370","GO:0051897","GO:0006700","GO:0006707","GO:0046427","GO:0018931","GO:0048661","GO:0007586","GO:0070301","GO:0046370","GO:2000353","GO:0001516","GO:0042415","GO:0019568","GO:0016488","GO:0048385","GO:0070485","GO:0072001","GO:0008584","GO:0072061","GO:0055114","GO:0097238","GO:0071277","GO:0097066","GO:1900053","GO:0030573","GO:0035809","GO:1901653","GO:0006061","GO:0006699","GO:2000224","GO:0071276","GO:0008209"]},{"accession":"XP_071820766.1","go_terms":["GO:0032922","GO:2000323","GO:0071000","GO:2000850","GO:0019915","GO:0009650","GO:0045475","GO:1902448","GO:0009638","GO:0042332","GO:0050980","GO:0009584","GO:0050958","GO:0048574","GO:0009588","GO:0033762","GO:1902347","GO:0006975","GO:0000719","GO:0042754","GO:0018298","GO:0009785","GO:0009646","GO:0010117","GO:0010343","GO:1901371","GO:1901332","GO:0010617","GO:0010075","GO:1901672","GO:0010244","GO:0045187","GO:2000001","GO:0043153","GO:0010118"]},{"accession":"XP_071815705.1","go_terms":["GO:0071555","GO:0010306","GO:0080147"]},{"accession":"XP_071832194.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:0002098"]},{"accession":"XP_071811646.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"XP_071823877.1","go_terms":["GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0006310","GO:0080111","GO:0007568","GO:0071320","GO:0042493","GO:0006313"]},{"accession":"XP_071829036.1","go_terms":["GO:0001824","GO:1905318","GO:0042138","GO:0090267","GO:0042177","GO:1990492","GO:0051312","GO:0051301","GO:0009556","GO:0009554","GO:0042787","GO:0010944","GO:1904667","GO:0048477","GO:0060629","GO:0000278","GO:0051177","GO:0051598","GO:0007130","GO:0042772","GO:0042276","GO:0000070","GO:0010719","GO:2000048","GO:0007094","GO:0044774","GO:2000678"]},{"accession":"XP_071834664.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"XP_071840516.1","go_terms":["GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0006310","GO:0080111","GO:0007568","GO:0071320","GO:0042493","GO:0006313"]},{"accession":"XP_071816146.1","go_terms":["GO:0071555","GO:0010306","GO:0080147"]},{"accession":"XP_071849182.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]}],"graph":[["XP_071811646.1","XP_071815015.1",0.908],["XP_071811646.1","XP_071815705.1",0.79],["XP_071811646.1","XP_071816146.1",0.703],["XP_071811646.1","XP_071820766.1",0.781],["XP_071811646.1","XP_071821858.1",0.775],["XP_071811646.1","XP_071823877.1",0.62],["XP_071811646.1","XP_071829036.1",0.823],["XP_071811646.1","XP_071832194.1",0.76],["XP_071811646.1","XP_071832662.1",0.838],["XP_071811646.1","XP_071834664.1",0.844],["XP_071811646.1","XP_071840516.1",0.613],["XP_071811646.1","XP_071849182.1",0.866],["XP_071815705.1","XP_071823877.1",0.756],["XP_071815705.1","XP_071821858.1",0.638],["XP_071815705.1","XP_071820766.1",0.901],["XP_071815705.1","XP_071815015.1",0.878],["XP_071815705.1","XP_071816146.1",0.771],["XP_071815705.1","XP_071834664.1",0.836],["XP_071815705.1","XP_071832194.1",0.866],["XP_071815705.1","XP_071832662.1",0.863],["XP_071815705.1","XP_071829036.1",0.507],["XP_071815705.1","XP_071849182.1",0.96],["XP_071815705.1","XP_071840516.1",0.912],["XP_071832662.1","XP_071815015.1",0.954],["XP_071832662.1","XP_071816146.1",0.644],["XP_071832662.1","XP_071820766.1",0.737],["XP_071832662.1","XP_071821858.1",0.808],["XP_071832662.1","XP_071823877.1",0.795],["XP_071832662.1","XP_071829036.1",0.985],["XP_071832662.1","XP_071832194.1",0.841],["XP_071832662.1","XP_071834664.1",0.86],["XP_071832662.1","XP_071840516.1",0.888],["XP_071832662.1","XP_071849182.1",0.94],["XP_071815015.1","XP_071823877.1",0.694],["XP_071815015.1","XP_071821858.1",0.968],["XP_071815015.1","XP_071820766.1",0.57],["XP_071815015.1","XP_071816146.1",0.539],["XP_071815015.1","XP_071834664.1",0.729],["XP_071815015.1","XP_071832194.1",0.88],["XP_071815015.1","XP_071829036.1",0.985],["XP_071815015.1","XP_071849182.1",0.951],["XP_071815015.1","XP_071840516.1",0.752],["XP_071834664.1","XP_071816146.1",0.665],["XP_071834664.1","XP_071820766.1",0.592],["XP_071834664.1","XP_071821858.1",0.81],["XP_071834664.1","XP_071823877.1",0.521],["XP_071834664.1","XP_071829036.1",0.69],["XP_071834664.1","XP_071832194.1",0.769],["XP_071834664.1","XP_071840516.1",0.678],["XP_071834664.1","XP_071849182.1",0.886],["XP_071821858.1","XP_071823877.1",0.809],["XP_071821858.1","XP_071829036.1",0.947],["XP_071821858.1","XP_071832194.1",0.812],["XP_071821858.1","XP_071840516.1",0.891],["XP_071821858.1","XP_071849182.1",0.971],["XP_071829036.1","XP_071816146.1",0.895],["XP_071829036.1","XP_071820766.1",0.537],["XP_071829036.1","XP_071823877.1",0.868],["XP_071829036.1","XP_071832194.1",0.883],["XP_071829036.1","XP_071840516.1",0.876],["XP_071829036.1","XP_071849182.1",0.905],["XP_071823877.1","XP_071816146.1",0.726],["XP_071823877.1","XP_071820766.1",0.822],["XP_071823877.1","XP_071832194.1",0.785],["XP_071823877.1","XP_071849182.1",0.85],["XP_071823877.1","XP_071840516.1",0.781],["XP_071840516.1","XP_071816146.1",0.799],["XP_071840516.1","XP_071820766.1",0.899],["XP_071840516.1","XP_071832194.1",0.743],["XP_071840516.1","XP_071849182.1",0.84],["XP_071820766.1","XP_071816146.1",0.788],["XP_071820766.1","XP_071832194.1",0.856],["XP_071820766.1","XP_071849182.1",0.938],["XP_071849182.1","XP_071816146.1",0.761],["XP_071849182.1","XP_071832194.1",0.872],["XP_071816146.1","XP_071832194.1",0.775]],"all_go_terms":{"GO:0045003":2,"GO:0030491":2,"GO:0010165":2,"GO:0009432":2,"GO:0009636":2,"GO:1990426":2,"GO:0071897":2,"GO:0042493":4,"GO:0006412":2,"GO:0007294":2,"GO:0051260":2,"GO:0090656":2,"GO:0000722":2,"GO:0007066":2,"GO:1904631":2,"GO:0006260":6,"GO:0006276":2,"GO:0072757":2,"GO:0007286":2,"GO:0001541":2,"GO:0010569":2,"GO:0072711":2,"GO:0071140":2,"GO:0010212":2,"GO:0000707":2,"GO:0000730":2,"GO:0007141":2,"GO:0030717":2,"GO:1990414":2,"GO:0090267":3,"GO:0072719":2,"GO:0042148":2,"GO:0006268":2,"GO:0009951":2,"GO:1990918":2,"GO:0007127":2,"GO:0032508":2,"GO:0001832":2,"GO:2000269":2,"GO:0007129":2,"GO:0006281":2,"GO:0006310":8,"GO:0001556":2,"GO:0051106":2,"GO:0000732":2,"GO:0007131":2,"GO:0009949":2,"GO:0000709":2,"GO:0007533":2,"GO:0071480":2,"GO:0001932":2,"GO:0036297":2,"GO:0007130":3,"GO:0042843":1,"GO:0097066":1,"GO:0031098":1,"GO:0060135":1,"GO:0071799":1,"GO:0042574":1,"GO:0061370":1,"GO:0070301":3,"GO:0006699":1,"GO:0055114":1,"GO:0044598":1,"GO:0046427":1,"GO:0019568":1,"GO:0071276":1,"GO:0008584":1,"GO:0071277":1,"GO:0030573":1,"GO:0046370":1,"GO:0001516":1,"GO:0072061":1,"GO:1901653":1,"GO:0016488":1,"GO:0006707":1,"GO:0042572":1,"GO:0009414":1,"GO:0048385":1,"GO:2000353":1,"GO:0018931":1,"GO:0097238":1,"GO:0070485":1,"GO:0008209":1,"GO:0006700":1,"GO:0035229":1,"GO:0042840":1,"GO:0003091":1,"GO:0001894":1,"GO:0071805":1,"GO:0006061":1,"GO:0071395":1,"GO:0051897":1,"GO:0019853":1,"GO:0006750":1,"GO:0042821":1,"GO:0043066":1,"GO:0044597":1,"GO:0042448":1,"GO:0007586":1,"GO:0042415":1,"GO:0035809":1,"GO:0072001":1,"GO:0048661":1,"GO:1900053":1,"GO:2000224":1,"GO:2000323":1,"GO:0032922":1,"GO:1901672":1,"GO:0010117":1,"GO:0009588":1,"GO:0010118":1,"GO:0010617":1,"GO:0009638":1,"GO:0048574":1,"GO:2000001":1,"GO:0009584":1,"GO:0071000":1,"GO:0006975":1,"GO:0019915":1,"GO:1902347":1,"GO:0009785":1,"GO:0050958":1,"GO:0009646":1,"GO:1902448":1,"GO:0000719":1,"GO:0018298":1,"GO:0009650":1,"GO:0010343":1,"GO:0010075":1,"GO:0045187":1,"GO:1901371":1,"GO:0042754":1,"GO:0050980":1,"GO:1901332":1,"GO:0042332":1,"GO:0043153":1,"GO:0010244":1,"GO:0045475":1,"GO:0033762":1,"GO:2000850":1,"GO:0071555":2,"GO:0010306":2,"GO:0080147":2,"GO:0075713":4,"GO:0075732":4,"GO:0015074":4,"GO:1903704":4,"GO:0002098":1,"GO:0039651":4,"GO:0046718":4,"GO:0006278":4,"GO:0006915":2,"GO:0090502":2,"GO:0006313":2,"GO:0006284":2,"GO:0006308":2,"GO:0046856":2,"GO:2000327":2,"GO:0003335":2,"GO:1903507":2,"GO:0043488":2,"GO:2000466":2,"GO:0007568":2,"GO:0080111":2,"GO:2001153":2,"GO:1900087":2,"GO:0071320":2,"GO:0071375":2,"GO:0045454":2,"GO:0044179":2,"GO:0014912":2,"GO:0042276":1,"GO:2000678":1,"GO:0042787":1,"GO:0042138":1,"GO:0048477":1,"GO:0044774":1,"GO:0000070":1,"GO:2000048":1,"GO:0051177":1,"GO:1905318":1,"GO:0042772":1,"GO:0007094":1,"GO:0001824":1,"GO:0010944":1,"GO:0000278":1,"GO:0010719":1,"GO:0009556":1,"GO:0051301":1,"GO:0051598":1,"GO:0060629":1,"GO:0009554":1,"GO:1990492":1,"GO:0051312":1,"GO:1904667":1,"GO:0042177":1},"recipe_readded":[]}