{"hash":"1657595942933488944","title":"Proteostasis and ER-associated degradation","description":"Dominant signals point to protein quality control and turnover: ribosome-associated ubiquitin-dependent degradation, cytosolic proteasome-mediated quality control, and ER-to-cytosol retrograde transport linked to ERAD. Together they indicate a focus on maintaining protein homeostasis through ubiquitin-proteasome\u2013driven degradation in cytosolic and ER contexts.","confidence":"High","size":3,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_071849622.1","go_terms":["GO:1990116","GO:1900182","GO:0030970","GO:0032480","GO:0071712","GO:0070651","GO:0051974","GO:0071629"]},{"accession":"XP_071812428.1","go_terms":["GO:1902475","GO:0008152"]},{"accession":"XP_071837651.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0051974":1,"GO:0030970":1,"GO:0070651":1,"GO:1900182":1,"GO:0071629":1,"GO:1990116":1,"GO:0071712":1,"GO:0032480":1,"GO:1902475":1,"GO:0008152":1},"recipe_readded":["XP_071840012.1","XP_071837791.1","XP_071847339.1","XP_071832880.1","XP_071829234.1","XP_071818202.1","XP_071834254.1","XP_071850641.1","XP_071828000.1","XP_071845619.1","XP_071827992.1","XP_071841231.1","XP_071840061.1","XP_071841120.1","XP_071811450.1","XP_071844193.1","XP_071812047.1","XP_071845977.1","XP_071827860.1","XP_071843506.1"]}