{"hash":"1050895786727017011","title":"Innate Immune Cytokine Signaling and Inflammasome Assembly","description":"This cluster is best described by its enrichment in innate immune and inflammatory functions: defense response to protozoan, IL-18 production, and positive regulation of NLRP3 inflammasome complex assembly and cytokine production. These terms point to a coherent theme of inflammasome-mediated cytokine signaling in innate immunity. The remaining terms related to synaptic assembly at NMJ, ER membrane fusion, and microtubule dynamics appear as broader cellular processes that can intersect with immune signaling but do not define the primary function of the cluster.","confidence":"Medium","size":5,"edges":4,"triangles":0,"max_degree":4,"top_function":null,"members":[{"accession":"XP_010980062.1","go_terms":[]},{"accession":"XP_031321400.2","go_terms":["GO:0071346","GO:0072616","GO:1903077","GO:0050860","GO:1900017","GO:0007030","GO:0051607","GO:0007029","GO:1900025","GO:0051260","GO:0050702","GO:1900227","GO:1900041","GO:0042832","GO:0008582","GO:0016320","GO:0007019","GO:0071158","GO:0051124","GO:0045687"]},{"accession":"XP_010990675.3","go_terms":["GO:0010923","GO:0042998"]},{"accession":"XP_031321404.2","go_terms":["GO:0071346","GO:0072616","GO:1903077","GO:0050860","GO:1900017","GO:0007030","GO:0051607","GO:0007029","GO:1900025","GO:0051260","GO:0050702","GO:1900227","GO:1900041","GO:0042832","GO:0008582","GO:0016320","GO:0007019","GO:0071158","GO:0051124","GO:0045687"]},{"accession":"XP_064349434.1","go_terms":["GO:0071346","GO:0072616","GO:1903077","GO:0050860","GO:1900017","GO:0007030","GO:0051607","GO:0007029","GO:1900025","GO:0051260","GO:0050702","GO:1900227","GO:1900041","GO:0042832","GO:0008582","GO:0016320","GO:0007019","GO:0071158","GO:0051124","GO:0045687"]}],"graph":[["XP_031321404.2","XP_010980062.1",0.555],["XP_010980062.1","XP_010990675.3",0.659],["XP_010980062.1","XP_031321400.2",0.756],["XP_010980062.1","XP_064349434.1",0.561]],"all_go_terms":{"GO:0071158":3,"GO:0042832":3,"GO:0008582":3,"GO:0016320":3,"GO:1900017":3,"GO:0007019":3,"GO:0072616":3,"GO:1903077":3,"GO:1900227":3,"GO:0051124":3,"GO:0050702":3,"GO:0071346":3,"GO:0007029":3,"GO:1900041":3,"GO:1900025":3,"GO:0050860":3,"GO:0051607":3,"GO:0045687":3,"GO:0007030":3,"GO:0051260":3,"GO:0042998":1,"GO:0010923":1},"recipe_readded":[]}