{"hash":"768355459495318911","title":"Translation Machinery and mRNA Turnover","description":"The term set is dominated by GO terms for translation at all stages (initiation, elongation, termination), ribosome disassembly, and mitochondrial translation, indicating a cluster of proteins involved in protein synthesis. The presence of cytoplasmic translation regulation and mRNA deadenylation-dependent decay reinforces the focus on translation and associated mRNA turnover; a single outlier term about heterochromatin regulation is relatively marginal.","confidence":"High","size":18,"edges":153,"triangles":816,"max_degree":17,"top_function":"ribosome biogenesis","members":[{"accession":"XP_062835125.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"XP_003226101.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"XP_008112746.2","go_terms":["GO:0000747","GO:0042274","GO:0000055","GO:0042254","GO:1901001","GO:0002181","GO:1903833","GO:0051301","GO:0006400","GO:0090529","GO:0007049","GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0002182","GO:0070966","GO:0070651","GO:0006415"]},{"accession":"XP_062820613.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0006415"]},{"accession":"XP_008112542.1","go_terms":["GO:0000462","GO:0006412"]},{"accession":"XP_008112748.1","go_terms":["GO:0000747","GO:0042274","GO:0000055","GO:0042254","GO:1901001","GO:0002181","GO:1903833","GO:0051301","GO:0006400","GO:0090529","GO:0007049","GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0002182","GO:0070966","GO:0070651","GO:0006415"]},{"accession":"XP_062816299.1","go_terms":["GO:0002181"]},{"accession":"XP_062818781.1","go_terms":["GO:0002548","GO:0007219","GO:0060265","GO:0060266","GO:0042274","GO:0042254","GO:0000028","GO:0007000","GO:0035284","GO:0006412","GO:0006407"]},{"accession":"XP_062826326.1","go_terms":["GO:0042255","GO:0046677","GO:0000448","GO:0006412"]},{"accession":"XP_062827686.1","go_terms":["GO:0050689","GO:0030423","GO:0030422","GO:0044387","GO:0045071","GO:0031053","GO:0031054","GO:0035280","GO:0070934","GO:0035455","GO:0009047","GO:1900369","GO:0097049","GO:0009615","GO:0009636","GO:0035087","GO:1902033","GO:0006364","GO:0045070","GO:0006382","GO:0010998","GO:0034474","GO:0008285","GO:0008033","GO:0046782","GO:0045087","GO:2000628","GO:0061744","GO:0046726","GO:0021610","GO:0021618","GO:0090502","GO:0016075","GO:0045433","GO:0035196","GO:0070919","GO:0021965","GO:0006397"]},{"accession":"XP_062827689.1","go_terms":["GO:0050689","GO:0030423","GO:0030422","GO:0044387","GO:0045071","GO:0031053","GO:0031054","GO:0035280","GO:0070934","GO:0035455","GO:0009047","GO:1900369","GO:0097049","GO:0009615","GO:0009636","GO:0035087","GO:1902033","GO:0006364","GO:0045070","GO:0006382","GO:0010998","GO:0034474","GO:0008285","GO:0008033","GO:0046782","GO:0045087","GO:2000628","GO:0061744","GO:0046726","GO:0021610","GO:0021618","GO:0090502","GO:0016075","GO:0045433","GO:0035196","GO:0070919","GO:0021965","GO:0006397"]},{"accession":"XP_062834991.1","go_terms":["GO:0050689","GO:0030423","GO:0030422","GO:0044387","GO:0045071","GO:0031053","GO:0031054","GO:0035280","GO:0070934","GO:0035455","GO:0009047","GO:1900369","GO:0097049","GO:0009615","GO:0009636","GO:0035087","GO:1902033","GO:0006364","GO:0045070","GO:0006382","GO:0010998","GO:0034474","GO:0008285","GO:0008033","GO:0046782","GO:0045087","GO:2000628","GO:0061744","GO:0046726","GO:0021610","GO:0021618","GO:0090502","GO:0016075","GO:0045433","GO:0035196","GO:0070919","GO:0021965","GO:0006397","GO:0042473","GO:0042474","GO:0007317","GO:0007316","GO:0045887","GO:0048132","GO:2001244","GO:0035418","GO:0007318"]},{"accession":"XP_003215968.1","go_terms":["GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0006415"]},{"accession":"XP_003216937.1","go_terms":["GO:0006415","GO:0032543","GO:0000027"]},{"accession":"XP_003217928.1","go_terms":["GO:0006450","GO:0006412","GO:0006407"]},{"accession":"XP_003218893.1","go_terms":["GO:0045903","GO:0001731","GO:0006413","GO:0006412","GO:0000288","GO:0045901","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006449","GO:0006415"]},{"accession":"XP_003223338.1","go_terms":["GO:0000747","GO:0042274","GO:0000055","GO:0042254","GO:1901001","GO:0002181","GO:1903833","GO:0051301","GO:0006400","GO:0090529","GO:0007049","GO:0000288","GO:0045901","GO:0045903","GO:0014009","GO:0002184","GO:0001514","GO:0046677","GO:0070125","GO:1902802","GO:2000767","GO:0032790","GO:0006413","GO:0006412","GO:0006449","GO:0019079","GO:0001172","GO:0002182","GO:0070966","GO:0070651","GO:0006415"]},{"accession":"XP_003225100.1","go_terms":["GO:0042254","GO:0006412"]}],"graph":[["XP_003226101.1","XP_003215968.1",0.955],["XP_003226101.1","XP_003216937.1",0.923],["XP_003226101.1","XP_003217928.1",0.948],["XP_003226101.1","XP_003218893.1",0.943],["XP_003226101.1","XP_003223338.1",0.961],["XP_003226101.1","XP_003225100.1",0.882],["XP_003226101.1","XP_008112746.2",0.968],["XP_003226101.1","XP_008112748.1",0.959],["XP_003226101.1","XP_008112542.1",0.889],["XP_003226101.1","XP_062820613.1",0.967],["XP_003226101.1","XP_062818781.1",0.927],["XP_003226101.1","XP_062816299.1",0.897],["XP_003226101.1","XP_062834991.1",0.978],["XP_003226101.1","XP_062835125.1",0.926],["XP_003226101.1","XP_062827686.1",0.977],["XP_003226101.1","XP_062827689.1",0.983],["XP_003226101.1","XP_062826326.1",0.933],["XP_008112746.2","XP_062820613.1",0.971],["XP_008112746.2","XP_062818781.1",0.936],["XP_008112746.2","XP_062816299.1",0.946],["XP_008112746.2","XP_062834991.1",0.975],["XP_008112746.2","XP_062835125.1",0.962],["XP_008112746.2","XP_062827686.1",0.971],["XP_008112746.2","XP_062827689.1",0.983],["XP_008112746.2","XP_062826326.1",0.965],["XP_008112746.2","XP_003215968.1",0.959],["XP_008112746.2","XP_003216937.1",0.948],["XP_008112746.2","XP_003217928.1",0.941],["XP_008112746.2","XP_003218893.1",0.948],["XP_008112746.2","XP_003223338.1",0.971],["XP_008112746.2","XP_003225100.1",0.96],["XP_008112746.2","XP_008112542.1",0.937],["XP_008112746.2","XP_008112748.1",0.975],["XP_008112748.1","XP_062820613.1",0.971],["XP_008112748.1","XP_062818781.1",0.951],["XP_008112748.1","XP_062816299.1",0.937],["XP_008112748.1","XP_062834991.1",0.982],["XP_008112748.1","XP_062835125.1",0.967],["XP_008112748.1","XP_062827686.1",0.97],["XP_008112748.1","XP_062827689.1",0.981],["XP_008112748.1","XP_062826326.1",0.97],["XP_008112748.1","XP_003215968.1",0.963],["XP_008112748.1","XP_003216937.1",0.953],["XP_008112748.1","XP_003217928.1",0.952],["XP_008112748.1","XP_003218893.1",0.95],["XP_008112748.1","XP_003223338.1",0.974],["XP_008112748.1","XP_003225100.1",0.939],["XP_008112748.1","XP_008112542.1",0.943],["XP_003216937.1","XP_003215968.1",0.97],["XP_003216937.1","XP_003217928.1",0.925],["XP_003216937.1","XP_003218893.1",0.937],["XP_003216937.1","XP_003223338.1",0.95],["XP_003216937.1","XP_003225100.1",0.876],["XP_003216937.1","XP_008112542.1",0.868],["XP_003216937.1","XP_062816299.1",0.898],["XP_003216937.1","XP_062818781.1",0.908],["XP_003216937.1","XP_062820613.1",0.948],["XP_003216937.1","XP_062826326.1",0.924],["XP_003216937.1","XP_062827686.1",0.967],["XP_003216937.1","XP_062827689.1",0.973],["XP_003216937.1","XP_062834991.1",0.977],["XP_003216937.1","XP_062835125.1",0.91],["XP_062826326.1","XP_008112542.1",0.904],["XP_062826326.1","XP_062816299.1",0.907],["XP_062826326.1","XP_062818781.1",0.865],["XP_062826326.1","XP_062820613.1",0.976],["XP_062826326.1","XP_062834991.1",0.989],["XP_062826326.1","XP_062835125.1",0.932],["XP_062826326.1","XP_062827686.1",0.972],["XP_062826326.1","XP_062827689.1",0.973],["XP_062826326.1","XP_003215968.1",0.971],["XP_062826326.1","XP_003217928.1",0.946],["XP_062826326.1","XP_003218893.1",0.955],["XP_062826326.1","XP_003223338.1",0.956],["XP_062826326.1","XP_003225100.1",0.934],["XP_062827686.1","XP_008112542.1",0.948],["XP_062827686.1","XP_062816299.1",0.972],["XP_062827686.1","XP_062818781.1",0.886],["XP_062827686.1","XP_062820613.1",0.98],["XP_062827686.1","XP_062827689.1",0.968],["XP_062827686.1","XP_062834991.1",0.984],["XP_062827686.1","XP_062835125.1",0.972],["XP_062827686.1","XP_003215968.1",0.963],["XP_062827686.1","XP_003217928.1",0.911],["XP_062827686.1","XP_003218893.1",0.968],["XP_062827686.1","XP_003223338.1",0.97],["XP_062827686.1","XP_003225100.1",0.966],["XP_062827689.1","XP_008112542.1",0.952],["XP_062827689.1","XP_062816299.1",0.973],["XP_062827689.1","XP_062818781.1",0.944],["XP_062827689.1","XP_062820613.1",0.982],["XP_062827689.1","XP_062834991.1",0.986],["XP_062827689.1","XP_062835125.1",0.977],["XP_062827689.1","XP_003215968.1",0.981],["XP_062827689.1","XP_003217928.1",0.902],["XP_062827689.1","XP_003218893.1",0.975],["XP_062827689.1","XP_003223338.1",0.986],["XP_062827689.1","XP_003225100.1",0.97],["XP_003223338.1","XP_003215968.1",0.958],["XP_003223338.1","XP_003217928.1",0.946],["XP_003223338.1","XP_003218893.1",0.945],["XP_003223338.1","XP_003225100.1",0.942],["XP_003223338.1","XP_008112542.1",0.941],["XP_003223338.1","XP_062820613.1",0.97],["XP_003223338.1","XP_062818781.1",0.95],["XP_003223338.1","XP_062816299.1",0.941],["XP_003223338.1","XP_062834991.1",0.979],["XP_003223338.1","XP_062835125.1",0.963],["XP_062818781.1","XP_008112542.1",0.919],["XP_062818781.1","XP_062816299.1",0.918],["XP_062818781.1","XP_062820613.1",0.929],["XP_062818781.1","XP_062834991.1",0.952],["XP_062818781.1","XP_062835125.1",0.938],["XP_062818781.1","XP_003215968.1",0.939],["XP_062818781.1","XP_003217928.1",0.931],["XP_062818781.1","XP_003218893.1",0.847],["XP_062818781.1","XP_003225100.1",0.889],["XP_062835125.1","XP_008112542.1",0.894],["XP_062835125.1","XP_062816299.1",0.919],["XP_062835125.1","XP_062820613.1",0.966],["XP_062835125.1","XP_062834991.1",0.976],["XP_062835125.1","XP_003215968.1",0.951],["XP_062835125.1","XP_003217928.1",0.943],["XP_062835125.1","XP_003218893.1",0.949],["XP_062835125.1","XP_003225100.1",0.868],["XP_003217928.1","XP_003215968.1",0.965],["XP_003217928.1","XP_003218893.1",0.935],["XP_003217928.1","XP_003225100.1",0.904],["XP_003217928.1","XP_008112542.1",0.885],["XP_003217928.1","XP_062816299.1",0.91],["XP_003217928.1","XP_062820613.1",0.944],["XP_003217928.1","XP_062834991.1",0.958],["XP_062816299.1","XP_008112542.1",0.859],["XP_062816299.1","XP_062820613.1",0.94],["XP_062816299.1","XP_062834991.1",0.972],["XP_062816299.1","XP_003215968.1",0.897],["XP_062816299.1","XP_003218893.1",0.838],["XP_062816299.1","XP_003225100.1",0.843],["XP_062820613.1","XP_008112542.1",0.936],["XP_062820613.1","XP_062834991.1",0.975],["XP_062820613.1","XP_003215968.1",0.951],["XP_062820613.1","XP_003218893.1",0.957],["XP_062820613.1","XP_003225100.1",0.939],["XP_008112542.1","XP_062834991.1",0.951],["XP_008112542.1","XP_003215968.1",0.928],["XP_008112542.1","XP_003218893.1",0.923],["XP_008112542.1","XP_003225100.1",0.737],["XP_003215968.1","XP_003225100.1",0.951],["XP_003215968.1","XP_003218893.1",0.861],["XP_003215968.1","XP_062834991.1",0.982],["XP_003218893.1","XP_003225100.1",0.903],["XP_003218893.1","XP_062834991.1",0.971],["XP_003225100.1","XP_062834991.1",0.977]],"all_go_terms":{"GO:0032790":8,"GO:1902802":8,"GO:0001172":6,"GO:0070125":8,"GO:0006412":13,"GO:0000288":8,"GO:2000767":8,"GO:0006415":9,"GO:0006413":8,"GO:0019079":6,"GO:0006449":8,"GO:0002184":8,"GO:0045901":8,"GO:0046677":9,"GO:0001514":8,"GO:0014009":8,"GO:0045903":8,"GO:0007049":3,"GO:0070966":3,"GO:0051301":3,"GO:0000747":3,"GO:1903833":3,"GO:0002181":4,"GO:0042274":4,"GO:0006400":3,"GO:0070651":3,"GO:0002182":3,"GO:0042254":5,"GO:0090529":3,"GO:0000055":3,"GO:1901001":3,"GO:0000462":1,"GO:0007000":1,"GO:0060265":1,"GO:0006407":2,"GO:0007219":1,"GO:0000028":1,"GO:0035284":1,"GO:0002548":1,"GO:0060266":1,"GO:0042255":1,"GO:0000448":1,"GO:0090502":3,"GO:0008033":3,"GO:0044387":3,"GO:0009615":3,"GO:0031053":3,"GO:0046782":3,"GO:0021965":3,"GO:0046726":3,"GO:0021618":3,"GO:0097049":3,"GO:0031054":3,"GO:0030423":3,"GO:0030422":3,"GO:0034474":3,"GO:0045070":3,"GO:0010998":3,"GO:0045071":3,"GO:0035196":3,"GO:0021610":3,"GO:0008285":3,"GO:0035087":3,"GO:1902033":3,"GO:1900369":3,"GO:0009047":3,"GO:0016075":3,"GO:0006397":3,"GO:0045433":3,"GO:0061744":3,"GO:0006364":3,"GO:0035455":3,"GO:0070919":3,"GO:0045087":3,"GO:0070934":3,"GO:2000628":3,"GO:0009636":3,"GO:0006382":3,"GO:0050689":3,"GO:0035280":3,"GO:0007318":1,"GO:0042474":1,"GO:0045887":1,"GO:2001244":1,"GO:0035418":1,"GO:0042473":1,"GO:0007317":1,"GO:0048132":1,"GO:0007316":1,"GO:0000027":1,"GO:0032543":1,"GO:0006450":1,"GO:0001731":1},"recipe_readded":[]}