{"hash":"968749898405553779","title":"Immune and ECM remodeling","description":"This cluster combines immune-related processes (T cell cytotoxicity, macrophage apoptosis) with tissue remodeling activities (bone resorption, basement membrane disassembly), suggesting coordinated immune-driven remodeling of the extracellular matrix. Peptide catabolism and catalytic activity regulation further support enzymatic activities in inflammatory remodeling, with some developmental/hormonal context (lung branching, thyroid hormone response) that can intersect these processes.","confidence":"Medium","size":11,"edges":40,"triangles":67,"max_degree":10,"top_function":null,"members":[{"accession":"XP_025878201.1","go_terms":[]},{"accession":"XP_015611285.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593"]},{"accession":"NP_001403908.1","go_terms":["GO:0099641","GO:0071480","GO:0032387","GO:0050821","GO:0032355","GO:0009644","GO:0030308","GO:0032463","GO:2000378","GO:0070309","GO:0006936","GO:0070141","GO:0031109","GO:0009408","GO:0007568","GO:0042542","GO:1900034","GO:0051403","GO:1905907"]},{"accession":"XP_015615655.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]},{"accession":"XP_015628665.1","go_terms":["GO:0019322","GO:0043523","GO:0021762","GO:0010041","GO:1904879","GO:0014070","GO:0032094","GO:0006740","GO:2000378","GO:0045471","GO:0009051","GO:0061052","GO:0042542","GO:0010734","GO:0006098","GO:0006695","GO:0043249","GO:0006006"]},{"accession":"XP_015630526.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593"]},{"accession":"XP_015634253.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]},{"accession":"XP_015636152.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593"]},{"accession":"NP_001389384.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]},{"accession":"NP_001406865.1","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]},{"accession":"XP_015611357.2","go_terms":["GO:0007614","GO:0034769","GO:0097067","GO:0071888","GO:0043129","GO:0060448","GO:0010813","GO:0010815","GO:1903955","GO:0045453","GO:0010839","GO:0051603","GO:0001957","GO:0030574","GO:0001913","GO:1903146","GO:0050790","GO:2000179","GO:0060441","GO:0046697","GO:0035593","GO:0009636","GO:0042493","GO:1990236","GO:1990237","GO:0043418","GO:0006508"]}],"graph":[["XP_015615655.1","XP_015636152.1",0.592],["XP_015615655.1","XP_015634253.1",0.621],["XP_015615655.1","XP_015630526.1",0.662],["XP_015615655.1","XP_015628665.1",0.654],["XP_015615655.1","XP_025878201.1",0.647],["XP_015615655.1","NP_001389384.1",0.553],["XP_015615655.1","NP_001403908.1",0.568],["XP_015615655.1","NP_001406865.1",0.569],["XP_015615655.1","XP_015611285.1",0.67],["XP_015615655.1","XP_015611357.2",0.76],["NP_001406865.1","NP_001403908.1",0.637],["NP_001406865.1","XP_015611357.2",0.507],["NP_001406865.1","XP_015630526.1",0.627],["NP_001406865.1","XP_025878201.1",0.851],["XP_015636152.1","XP_015630526.1",0.694],["XP_015636152.1","XP_015634253.1",0.602],["XP_015636152.1","NP_001403908.1",0.577],["XP_015636152.1","XP_015611285.1",0.518],["NP_001389384.1","NP_001403908.1",0.542],["NP_001389384.1","XP_015611285.1",0.536],["NP_001389384.1","XP_015611357.2",0.697],["NP_001389384.1","XP_015630526.1",0.596],["NP_001389384.1","XP_025878201.1",0.512],["XP_015611285.1","NP_001403908.1",0.509],["XP_015611285.1","XP_015611357.2",0.543],["XP_015611285.1","XP_015628665.1",0.664],["XP_015611285.1","XP_015630526.1",0.755],["XP_015628665.1","XP_015634253.1",0.77],["XP_015628665.1","XP_015630526.1",0.799],["XP_015628665.1","NP_001403908.1",0.844],["XP_015628665.1","XP_015611357.2",0.647],["XP_015611357.2","NP_001403908.1"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