{"hash":"739957951467359375","title":"GPI-anchored membrane protein processing and trafficking","description":"This cluster centers on membrane-associated protein handling: GPI anchor biosynthesis, proteolysis of membrane proteins at ectodomain and intracellular domains, ER-to-cytosol retrograde transport, ER exit and surface localization. The inclusion of regulators of calcineurin-NFAT signaling and immune response suggests calcium-dependent signaling outputs tied to membrane processing and trafficking. A few terms like pseudohyphal growth may reflect broader regulatory contexts, but the dominant theme is membrane protein processing and trafficking.","confidence":"Medium","size":7,"edges":6,"triangles":0,"max_degree":5,"top_function":null,"members":[{"accession":"NP_001409978.1","go_terms":[]},{"accession":"NP_001409110.1","go_terms":[]},{"accession":"XP_066162873.1","go_terms":["GO:0006506"]},{"accession":"NP_001389489.1","go_terms":["GO:0050776","GO:1904211","GO:0051533","GO:0006509","GO:0070886","GO:0031293"]},{"accession":"NP_039431.1","go_terms":[]},{"accession":"XP_015643239.1","go_terms":["GO:0007124","GO:0001403","GO:2000010","GO:0033299","GO:0061060","GO:0070863"]},{"accession":"XP_025875756.1","go_terms":[]}],"graph":[["XP_025875756.1","NP_001389489.1",0.674],["NP_001409978.1","NP_001389489.1",0.706],["NP_001409978.1","XP_015643239.1",0.711],["XP_066162873.1","NP_001389489.1",0.541],["NP_001389489.1","NP_001409110.1",0.751],["NP_001389489.1","NP_039431.1",0.885]],"all_go_terms":{"GO:0006506":1,"GO:0006509":1,"GO:0051533":1,"GO:1904211":1,"GO:0070886":1,"GO:0050776":1,"GO:0031293":1,"GO:0070863":1,"GO:2000010":1,"GO:0007124":1,"GO:0001403":1,"GO:0033299":1,"GO:0061060":1},"recipe_readded":[]}