{"hash":"502874187702060372","title":"Innate immune signaling regulators","description":"The cluster shows enrichment for regulatory roles in antiviral innate signaling (negative regulation of RIG-I and MDA-5 pathways, negative regulation of interferon production), as well as modulation of complement activation and dendritic cell chemotaxis, with additional links to PI3K/AKT signaling. This pattern points to a cohesive function in modulating innate immune responses rather than a single metabolic process, justifying a label focused on innate immune signaling regulation.","confidence":"High","size":7,"edges":2,"triangles":0,"max_degree":1,"top_function":null,"members":[{"accession":"XP_015628098.1","go_terms":["GO:0030449","GO:0035042","GO:0048025","GO:0051897","GO:0070131","GO:0090023","GO:1900026","GO:0042256","GO:0032695","GO:1901165","GO:2000510","GO:0014065","GO:0039536","GO:0039534","GO:0032689"]},{"accession":"XP_015633300.1","go_terms":[]},{"accession":"XP_015625323.1","go_terms":["GO:0006355","GO:0042391","GO:0015701","GO:1902476","GO:1902358","GO:0019532","GO:0030435","GO:0001696","GO:0048240","GO:0051454","GO:0089712","GO:0007605","GO:0015755"]},{"accession":"XP_015639249.1","go_terms":["GO:0006412"]},{"accession":"NP_001411130.1","go_terms":["GO:0070126","GO:0006412"]},{"accession":"XP_015636963.1","go_terms":["GO:0033617","GO:0006123","GO:0042776"]},{"accession":"XP_015642570.1","go_terms":[]}],"graph":[["XP_015639249.1","NP_001411130.1",0.91],["XP_015636963.1","XP_015633300.1",0.508]],"all_go_terms":{"GO:0070131":1,"GO:0039536":1,"GO:0035042":1,"GO:0051897":1,"GO:0039534":1,"GO:2000510":1,"GO:0032689":1,"GO:1900026":1,"GO:0030449":1,"GO:0090023":1,"GO:0032695":1,"GO:1901165":1,"GO:0014065":1,"GO:0042256":1,"GO:0048025":1,"GO:0048240":1,"GO:1902358":1,"GO:0015755":1,"GO:0042391":1,"GO:0030435":1,"GO:0007605":1,"GO:1902476":1,"GO:0015701":1,"GO:0006355":1,"GO:0019532":1,"GO:0001696":1,"GO:0089712":1,"GO:0051454":1,"GO:0006412":2,"GO:0070126":1,"GO:0033617":1,"GO:0042776":1,"GO:0006123":1},"recipe_readded":["XP_015634084.1","NP_001404413.1","XP_066162031.1","XP_015611210.1","NP_001411236.1","XP_015637139.1","XP_066165930.1","XP_015632078.1","XP_015632886.1","XP_015614980.1","XP_015643039.1","XP_015612499.1","XP_015648189.1","XP_015614317.1","XP_025878741.1","XP_015618377.1","NP_001405768.1","XP_015610976.1","XP_015645460.1","XP_015629395.1"]}