{"hash":"485219807552240344","title":"ER targeting and ERAD","description":"The top GO terms are dominated by processes of SRP-dependent cotranslational targeting to the membrane, ER-to-cytosol retrograde transport (ERAD), and post-translational targeting to membranes. This points to a cluster of proteins involved in directing nascent and processed proteins to the ER membrane, monitoring quality, and routing them for degradation when needed, with a broader tie to membrane trafficking. A few immune-defense terms appear but are likely secondary annotations; the core theme is ER-focused protein targeting and quality control.","confidence":"Medium","size":5,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_015650877.1","go_terms":["GO:0043547","GO:0000060","GO:0030970","GO:0006616","GO:0030433","GO:0031204"]},{"accession":"XP_015627638.1","go_terms":[]},{"accession":"XP_066160533.1","go_terms":["GO:0046688"]},{"accession":"XP_015629619.1","go_terms":["GO:0050688","GO:0017148","GO:0031640","GO:0050832","GO:0051607"]},{"accession":"XP_066163316.1","go_terms":["GO:0046718","GO:0006313","GO:0075713","GO:0032197","GO:0015074","GO:0075732","GO:0039651"]}],"graph":[],"all_go_terms":{"GO:0030433":1,"GO:0043547":1,"GO:0030970":1,"GO:0006616":1,"GO:0000060":1,"GO:0031204":1,"GO:0046688":1,"GO:0031640":1,"GO:0050688":1,"GO:0050832":1,"GO:0017148":1,"GO:0051607":1,"GO:0075732":1,"GO:0006313":1,"GO:0046718":1,"GO:0032197":1,"GO:0015074":1,"GO:0075713":1,"GO:0039651":1},"recipe_readded":["NP_039423.1"]}