{"hash":"1434325914044816310","title":"Meiosis I Spindle Assembly and Oocyte Maturation","description":"The top GO terms converge on meiotic spindle dynamics and oocyte maturation (microtubule polymerization; spindle assembly in female meiosis I; oocyte maturation) and on proteostasis and cell-cycle regulation (SCF-dependent ubiquitin-mediated proteolysis; negative regulation of cell proliferation). While there are a few neural-development terms in the list, the strongest signal is female meiosis/oocyte development and associated protein degradation pathways, suggesting a cluster of proteins functioning in meiotic progression and oocyte maturation, with linked cell-cycle control. Medium","confidence":"","size":8,"edges":26,"triangles":45,"max_degree":7,"top_function":null,"members":[{"accession":"XP_015618131.1","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556","GO:0060386","GO:0031571","GO:0071406","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"XP_015642386.1","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556","GO:0060386","GO:0031571","GO:0071406","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"XP_025882409.1","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556","GO:0060386","GO:0031571","GO:0071406","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"XP_025883079.2","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556","GO:0060386","GO:0031571","GO:0071406","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"XP_066165322.1","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556","GO:0060386","GO:0031571","GO:0071406","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"XP_066166479.1","go_terms":[]},{"accession":"XP_066168365.1","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556"]},{"accession":"XP_015635046.1","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556","GO:0060386","GO:0031571","GO:0071406","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]}],"graph":[["XP_015642386.1","XP_015618131.1",0.932],["XP_015642386.1","XP_015635046.1",0.524],["XP_015642386.1","XP_025882409.1",0.738],["XP_015642386.1","XP_025883079.2",0.906],["XP_015642386.1","XP_066165322.1",0.842],["XP_015642386.1","XP_066166479.1",0.962],["XP_015642386.1","XP_066168365.1",0.625],["XP_015618131.1","XP_015635046.1",0.938],["XP_015618131.1","XP_066168365.1",0.596],["XP_015618131.1","XP_066166479.1",0.855],["XP_015618131.1","XP_066165322.1",0.662],["XP_015618131.1","XP_025883079.2",0.952],["XP_015618131.1","XP_025882409.1",0.779],["XP_066168365.1","XP_015635046.1",0.604],["XP_066168365.1","XP_025882409.1",0.885],["XP_066168365.1","XP_025883079.2",0.891],["XP_066168365.1","XP_066166479.1",0.694],["XP_066165322.1","XP_025882409.1",0.967],["XP_066165322.1","XP_025883079.2",0.906],["XP_066165322.1","XP_066166479.1",0.952],["XP_025883079.2","XP_015635046.1",0.857],["XP_025883079.2","XP_025882409.1",0.962],["XP_025883079.2","XP_066166479.1",0.883],["XP_025882409.1","XP_015635046.1",0.938],["XP_025882409.1","XP_066166479.1",0.972],["XP_066166479.1","XP_015635046.1",0.858]],"all_go_terms":{"GO:0042752":6,"GO:0046785":7,"GO:0007057":7,"GO:0030174":6,"GO:0042787":6,"GO:0031146":7,"GO:0046685":6,"GO:0031571":6,"GO:0071276":6,"GO:1902916":6,"GO:0060386":6,"GO:0021678":7,"GO:0000083":6,"GO:0006516":7,"GO:1903378":6,"GO:0021993":7,"GO:0051436":7,"GO:0001556":7,"GO:0071406":6,"GO:0070544":7,"GO:0008285":7,"GO:0000209":6},"recipe_readded":[]}