{"hash":"762912646690427343","title":"Eukaryotic translation initiation machinery","description":"Dominant GO terms point to translation initiation, preinitiation complex formation, and eIF4F assembly (including IRES-dependent initiation and translation reinitiation), which strongly suggests the proteins function as components of the eukaryotic translation initiation machinery. Some regulatory terms about mRNA splicing and stability are present but appear ancillary to the main translation initiation theme.","confidence":"High","size":22,"edges":197,"triangles":977,"max_degree":21,"top_function":"regulatory ncRNA-mediated gene silencing","members":[{"accession":"XP_008194192.3","go_terms":[]},{"accession":"XP_008195186.1","go_terms":[]},{"accession":"XP_008201459.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_015836833.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_969016.4","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_969323.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_972805.1","go_terms":[]},{"accession":"XP_976197.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378","GO:0071230","GO:0046011","GO:1900365","GO:0071456","GO:1900248","GO:0008069","GO:0061158","GO:0060213","GO:0007310","GO:0032869","GO:0002931","GO:0045451"]},{"accession":"XP_064213165.1","go_terms":["GO:1902213","GO:0050775","GO:0009955","GO:0097150","GO:0048366","GO:1900170","GO:0016358","GO:0048013"]},{"accession":"XP_975882.1","go_terms":[]},{"accession":"NP_001161320.1","go_terms":["GO:0008363"]},{"accession":"NP_001182329.1","go_terms":[]},{"accession":"XP_001814998.2","go_terms":[]},{"accession":"XP_008191643.1","go_terms":[]},{"accession":"XP_008197899.1","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_008200145.1","go_terms":["GO:0008363"]},{"accession":"XP_015833878.1","go_terms":[]},{"accession":"XP_064214206.1","go_terms":[]},{"accession":"XP_969947.3","go_terms":["GO:0008363"]},{"accession":"XP_972024.2","go_terms":["GO:1905663","GO:1902625","GO:0048025","GO:0048026","GO:0075522","GO:0075525","GO:0000380","GO:0016556","GO:0001825","GO:1900363","GO:0002188","GO:0000381","GO:1903586","GO:0006406","GO:0006446","GO:0060211","GO:0031047","GO:0048255","GO:0035278","GO:0001731","GO:0010610","GO:0045292","GO:1901407","GO:0097010","GO:0006376","GO:0034462","GO:0006378"]},{"accession":"XP_975051.1","go_terms":["GO:0050766","GO:0033144","GO:0006457","GO:0030968","GO:0002502","GO:1900026","GO:2000510","GO:0090398","GO:0010204","GO:0048916","GO:1901224","GO:0007339","GO:0048387","GO:0048488","GO:0071157"]},{"accession":"XP_008191362.2","go_terms":["GO:0008363"]}],"graph":[["XP_008191643.1","NP_001161320.1",0.58],["XP_008191643.1","XP_001814998.2",0.762],["XP_008191643.1","XP_008191362.2",0.503],["XP_008191643.1","XP_008194192.3",0.542],["XP_008191643.1","XP_008197899.1",0.84],["XP_008191643.1","XP_008200145.1",0.73],["XP_008191643.1","XP_008201459.1",0.815],["XP_008191643.1","XP_015833878.1",0.823],["XP_008191643.1","XP_015836833.1",0.546],["XP_008191643.1","XP_064214206.1",0.807],["XP_008191643.1","XP_969016.4",0.856],["XP_008191643.1","XP_969323.1",0.715],["XP_008191643.1","XP_969947.3",0.842],["XP_008191643.1","XP_972024.2",0.89],["XP_008191643.1","XP_972805.1",0.865],["XP_008191643.1","XP_975051.1",0.92],["XP_008191643.1","XP_975882.1",0.703],["XP_008191643.1","XP_976197.1",0.726],["XP_001814998.2","NP_001161320.1",0.747],["XP_001814998.2","NP_001182329.1",0.605],["XP_001814998.2","XP_015836833.1",0.675],["XP_001814998.2","XP_008201459.1",0.797],["XP_001814998.2","XP_008200145.1",0.743],["XP_001814998.2","XP_008197899.1",0.79],["XP_001814998.2","XP_008194192.3",0.621],["XP_001814998.2","XP_008191362.2",0.526],["XP_001814998.2","XP_975051.1",0.863],["XP_001814998.2","XP_975882.1",0.8],["XP_001814998.2","XP_976197.1",0.731],["XP_001814998.2","XP_972805.1",0.784],["XP_001814998.2","XP_972024.2",0.705],["XP_001814998.2","XP_969947.3",0.871],["XP_001814998.2","XP_969016.4",0.791],["XP_001814998.2","XP_969323.1",0.522],["XP_001814998.2","XP_064214206.1",0.884],["XP_969016.4","NP_001161320.1",0.847],["XP_969016.4","NP_001182329.1",0.76],["XP_969016.4","XP_008191362.2",0.549],["XP_969016.4","XP_008194192.3",0.905],["XP_969016.4","XP_008195186.1",0.815],["XP_969016.4","XP_008197899.1",0.848],["XP_969016.4","XP_008200145.1",0.771],["XP_969016.4","XP_008201459.1",0.899],["XP_969016.4","XP_015836833.1",0.859],["XP_969016.4","XP_064213165.1",0.856],["XP_969016.4","XP_064214206.1",0.872],["XP_969016.4","XP_969323.1",0.838],["XP_969016.4","XP_969947.3",0.921],["XP_969016.4","XP_972024.2",0.937],["XP_969016.4","XP_972805.1",0.906],["XP_969016.4","XP_975051.1",0.938],["XP_969016.4","XP_976197.1",0.878],["XP_008200145.1","NP_001161320.1",0.616],["XP_008200145.1","XP_008191362.2",0.654],["XP_008200145.1","XP_008194192.3",0.747],["XP_008200145.1","XP_008195186.1",0.812],["XP_008200145.1","XP_008197899.1",0.837],["XP_008200145.1","XP_008201459.1",0.74],["XP_008200145.1","XP_015833878.1",0.827],["XP_008200145.1","XP_015836833.1",0.592],["XP_008200145.1","XP_975051.1",0.932],["XP_008200145.1","XP_975882.1",0.783],["XP_008200145.1","XP_976197.1",0.69],["XP_008200145.1","XP_972805.1",0.831],["XP_008200145.1","XP_972024.2",0.802],["XP_008200145.1","XP_969947.3",0.865],["XP_008200145.1","XP_969323.1",0.603],["XP_008200145.1","XP_064213165.1",0.558],["XP_008200145.1","XP_064214206.1",0.875],["XP_008195186.1","NP_001161320.1",0.749],["XP_008195186.1","NP_001182329.1",0.676],["XP_008195186.1","XP_008194192.3",0.829],["XP_008195186.1","XP_008197899.1",0.94],["XP_008195186.1","XP_008201459.1",0.972],["XP_008195186.1","XP_015833878.1",0.911],["XP_008195186.1","XP_015836833.1",0.778],["XP_008195186.1","XP_064214206.1",0.831],["XP_008195186.1","XP_969947.3",0.526],["XP_008195186.1","XP_972805.1",0.86],["XP_008195186.1","XP_975882.1",0.789],["XP_008195186.1","XP_976197.1",0.978],["XP_969947.3","NP_001161320.1",0.835],["XP_969947.3","NP_001182329.1",0.764],["XP_969947.3","XP_008191362.2",0.847],["XP_969947.3","XP_008194192.3",0.774],["XP_969947.3","XP_008197899.1",0.909],["XP_969947.3","XP_008201459.1",0.837],["XP_969947.3","XP_015833878.1",0.899],["XP_969947.3","XP_015836833.1",0.801],["XP_969947.3","XP_064213165.1",0.753],["XP_969947.3","XP_064214206.1",0.863],["XP_969947.3","XP_969323.1",0.9],["XP_969947.3","XP_975051.1",0.899],["XP_969947.3","XP_975882.1",0.843],["XP_969947.3","XP_976197.1",0.823],["XP_969947.3","XP_972805.1",0.889],["XP_969947.3","XP_972024.2",0.929],["XP_975882.1","NP_001161320.1",0.858],["XP_975882.1","NP_001182329.1",0.687],["XP_975882.1","XP_008194192.3",0.642],["XP_975882.1","XP_015833878.1",0.828],["XP_975882.1","XP_015836833.1",0.721],["XP_975882.1","XP_064213165.1",0.793],["XP_975882.1","XP_064214206.1",0.869],["XP_975882.1","XP_969323.1",0.858],["XP_975882.1","XP_972805.1",0.63],["XP_975882.1","XP_975051.1",0.837],["XP_008194192.3","NP_001161320.1",0.755],["XP_008194192.3","NP_001182329.1",0.699],["XP_008194192.3","XP_008191362.2",0.59],["XP_008194192.3","XP_015836833.1",0.737],["XP_008194192.3","XP_008201459.1",0.911],["XP_008194192.3","XP_008197899.1",0.813],["XP_008194192.3","XP_975051.1",0.907],["XP_008194192.3","XP_976197.1",0.911],["XP_008194192.3","XP_972805.1",0.914],["XP_008194192.3","XP_972024.2",0.902],["XP_008194192.3","XP_969323.1",0.898],["XP_008194192.3","XP_064213165.1",0.795],["XP_008194192.3","XP_064214206.1",0.874],["XP_969323.1","NP_001161320.1",0.91],["XP_969323.1","NP_001182329.1",0.761],["XP_969323.1","XP_008197899.1",0.709],["XP_969323.1","XP_008201459.1",0.759],["XP_969323.1","XP_015836833.1",0.849],["XP_969323.1","XP_064213165.1",0.855],["XP_969323.1","XP_064214206.1",0.917],["XP_969323.1","XP_972024.2",0.916],["XP_969323.1","XP_972805.1",0.862],["XP_969323.1","XP_975051.1",0.834],["XP_969323.1","XP_976197.1",0.685],["XP_064214206.1","NP_001161320.1",0.847],["XP_064214206.1","NP_001182329.1",0.851],["XP_064214206.1","XP_008191362.2",0.896],["XP_064214206.1","XP_008197899.1",0.862],["XP_064214206.1","XP_008201459.1",0.753],["XP_064214206.1","XP_015833878.1",0.727],["XP_064214206.1","XP_015836833.1",0.872],["XP_064214206.1","XP_975051.1",0.8],["XP_064214206.1","XP_976197.1",0.705],["XP_064214206.1","XP_972805.1",0.897],["XP_064214206.1","XP_972024.2",0.884],["XP_064214206.1","XP_064213165.1",0.846],["NP_001161320.1","XP_008191362.2",0.619],["NP_001161320.1","XP_008197899.1",0.734],["NP_001161320.1","XP_008201459.1",0.919],["NP_001161320.1","XP_015833878.1",0.852],["NP_001161320.1","XP_972024.2",0.875],["NP_001161320.1","XP_972805.1",0.863],["NP_001161320.1","XP_975051.1",0.919],["NP_001161320.1","XP_976197.1",0.893],["XP_015836833.1","XP_008191362.2",0.524],["XP_015836833.1","XP_008197899.1",0.636],["XP_015836833.1","XP_008201459.1",0.916],["XP_015836833.1","XP_015833878.1",0.759],["XP_015836833.1","XP_975051.1",0.871],["XP_015836833.1","XP_976197.1",0.921],["XP_015836833.1","XP_972805.1",0.838],["XP_015836833.1","XP_972024.2",0.91],["XP_976197.1","NP_001182329.1",0.617],["XP_976197.1","XP_008197899.1",0.932],["XP_976197.1","XP_008201459.1",0.982],["XP_976197.1","XP_064213165.1",0.897],["XP_976197.1","XP_972024.2",0.824],["XP_976197.1","XP_972805.1",0.972],["XP_976197.1","XP_975051.1",0.843],["XP_972024.2","NP_001182329.1",0.833],["XP_972024.2","XP_008191362.2",0.652],["XP_972024.2","XP_008197899.1",0.802],["XP_972024.2","XP_008201459.1",0.822],["XP_972024.2","XP_064213165.1",0.86],["XP_972024.2","XP_972805.1",0.835],["XP_972024.2","XP_975051.1",0.899],["XP_015833878.1","NP_001182329.1",0.75],["XP_015833878.1","XP_008191362.2",0.674],["XP_015833878.1","XP_008197899.1",0.734],["XP_015833878.1","XP_064213165.1",0.87],["XP_015833878.1","XP_972805.1",0.893],["XP_015833878.1","XP_975051.1",0.843],["XP_064213165.1","XP_008191362.2",0.52],["XP_064213165.1","XP_008197899.1",0.578],["XP_064213165.1","XP_008201459.1",0.891],["XP_064213165.1","XP_975051.1",0.903],["XP_064213165.1","XP_972805.1",0.875],["XP_008197899.1","NP_001182329.1",0.519],["XP_008197899.1","XP_008191362.2",0.672],["XP_008197899.1","XP_008201459.1",0.935],["XP_008197899.1","XP_972805.1",0.876],["XP_008197899.1","XP_975051.1",0.914],["XP_008191362.2","XP_972805.1",0.74],["XP_008191362.2","XP_975051.1",0.893],["XP_008201459.1","NP_001182329.1",0.788],["XP_008201459.1","XP_972805.1",0.969],["XP_008201459.1","XP_975051.1",0.787],["XP_975051.1","NP_001182329.1",0.876],["XP_975051.1","XP_972805.1",0.934],["NP_001182329.1","XP_972805.1",0.748]],"all_go_terms":{"GO:1900248":3,"GO:0075522":7,"GO:1900365":3,"GO:0071230":3,"GO:0032869":3,"GO:0097010":7,"GO:0002188":7,"GO:1902625":7,"GO:0060213":3,"GO:1905663":7,"GO:0001731":7,"GO:0048025":7,"GO:0000381":7,"GO:0010610":7,"GO:0007310":3,"GO:0006378":7,"GO:0002931":3,"GO:0016556":7,"GO:0045451":3,"GO:0045292":7,"GO:0031047":7,"GO:1901407":7,"GO:0001825":7,"GO:0006406":7,"GO:0006376":7,"GO:0071456":3,"GO:0006446":7,"GO:0060211":7,"GO:0046011":3,"GO:0000380":7,"GO:0008069":3,"GO:0048255":7,"GO:1903586":7,"GO:1900363":7,"GO:0035278":7,"GO:0061158":3,"GO:0034462":7,"GO:0048026":7,"GO:0075525":7,"GO:0097150":1,"GO:0048366":1,"GO:1900170":1,"GO:0048013":1,"GO:0050775":1,"GO:1902213":1,"GO:0016358":1,"GO:0009955":1,"GO:0008363":4,"GO:1901224":1,"GO:0050766":1,"GO:0030968":1,"GO:0071157":1,"GO:2000510":1,"GO:0048916":1,"GO:0006457":1,"GO:0010204":1,"GO:0002502":1,"GO:1900026":1,"GO:0007339":1,"GO:0048488":1,"GO:0090398":1,"GO:0048387":1,"GO:0033144":1},"recipe_readded":[]}