{"hash":"377818793216340891","title":"Retroviral entry, integration, and latency","description":"The terms cluster around steps of a retroviral life cycle: entry into the host cell and nucleus, reverse transcription (RNA-templated DNA synthesis), integration of viral DNA into the host genome, and establishment of proviral latency, with supporting roles for host DNA repair and apoptosis pathways. This coherent theme supports naming the cluster as Retroviral entry, integration, and latency.","confidence":"High","size":14,"edges":71,"triangles":191,"max_degree":13,"top_function":"DNA replication","members":[{"accession":"NP_001280508.1","go_terms":["GO:0006286","GO:0006287","GO:0006297","GO:1990506","GO:0006290","GO:0061674","GO:0006284","GO:0006288","GO:0051402","GO:0006954","GO:0008630","GO:0055093","GO:0007435","GO:0007568","GO:0048872","GO:0045471","GO:0010332","GO:0071707","GO:0048536","GO:0048535","GO:0016579","GO:0071897","GO:0016446","GO:0006303","GO:0071480","GO:0009636","GO:0051106","GO:0009432","GO:0010165","GO:0007127","GO:1990426","GO:0006260","GO:0032508","GO:0072757","GO:0072719","GO:0072711","GO:0042148","GO:0007131","GO:1904631","GO:0045003","GO:0000730","GO:0000732","GO:1990414","GO:0001932","GO:0006412"]},{"accession":"NP_001035796.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:0030422","GO:0030177","GO:0043249","GO:0046326","GO:1902895","GO:0032092","GO:0010449","GO:0042635","GO:2000648","GO:1904173","GO:0007004","GO:0022616","GO:0070200","GO:0071456","GO:0007571","GO:1903620","GO:0060729","GO:0010073","GO:0090399","GO:2001240","GO:1904751","GO:1904754","GO:0051000","GO:2000773"]},{"accession":"XP_064211184.1","go_terms":[]},{"accession":"XP_971585.2","go_terms":["GO:0071494","GO:0006297","GO:0042276","GO:0070987","GO:0006261"]},{"accession":"XP_973632.1","go_terms":["GO:0042254","GO:0000447","GO:0006412"]},{"accession":"XP_064214101.1","go_terms":["GO:0015074"]},{"accession":"XP_064214556.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"XP_064215705.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:0006313"]},{"accession":"XP_973868.2","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704","GO:2000327","GO:0014912","GO:0003335","GO:2001153","GO:0045454","GO:0071375","GO:0043488","GO:0044179","GO:0006308","GO:0046856","GO:1900087","GO:0090502","GO:0006284","GO:0070301","GO:2000466","GO:0006915","GO:1903507","GO:0080111","GO:0007568","GO:0071320","GO:0042493","GO:0006313"]},{"accession":"XP_008192389.2","go_terms":[]},{"accession":"XP_064211141.1","go_terms":["GO:0046718","GO:0006310","GO:0006278","GO:0075713","GO:0075732","GO:0015074","GO:0006260","GO:0039651","GO:1903704"]},{"accession":"XP_064214981.1","go_terms":["GO:0015074"]},{"accession":"XP_008196113.1","go_terms":["GO:0006295","GO:0006286","GO:0045876","GO:0006284","GO:0035753","GO:0045190","GO:0090267","GO:0007613","GO:0006289","GO:0031292","GO:0002455","GO:0001302","GO:0000734","GO:0006260","GO:0016446","GO:1903469","GO:0071140"]},{"accession":"XP_064211278.1","go_terms":["GO:0006909","GO:0071847","GO:0035750","GO:0043652","GO:0097107","GO:0090162","GO:0060997","GO:0060017","GO:0035176","GO:1902498","GO:0051660","GO:0048170","GO:1900273","GO:0045794","GO:0031666","GO:0016560","GO:0071625","GO:1901076","GO:0090557","GO:0061847","GO:2000394","GO:0060378","GO:0001568","GO:1900044","GO:1904424","GO:2000463","GO:0009887","GO:0030890","GO:1904888","GO:0034260","GO:0001771","GO:0043552","GO:0090110","GO:0050894","GO:0002051","GO:0001878","GO:0051968","GO:1904717","GO:0010923","GO:0032287","GO:0035020","GO:0035023","GO:0071800","GO:0007264","GO:1900026","GO:0008286","GO:0007015","GO:0061462","GO:0021773","GO:2000969","GO:0009952","GO:0035156","GO:0060291","GO:0060292","GO:0070830","GO:0071896","GO:1990090","GO:1903356","GO:0014911","GO:0030032","GO:0060022","GO:0060348","GO:1903753","GO:1990859","GO:0045953","GO:0048538","GO:0051835","GO:1904179","GO:0035728","GO:2001205","GO:1903760","GO:1903286","GO:1903764","GO:1990314","GO:0060124","GO:2000822","GO:2000821","GO:0007507","GO:0071732","GO:0097114","GO:0097117","GO:0097113","GO:0034446","GO:0051282","GO:1903676","GO:0030041","GO:0051044","GO:0044855","GO:1902951","GO:0033146","GO:0070667","GO:1904531","GO:0007173","GO:0010976","GO:0051666","GO:0042997","GO:1900275","GO:0016191","GO:0002774","GO:0050731","GO:0060988","GO:0046847","GO:1903898","GO:0090263","GO:1904528","GO:1902237","GO:0048008","GO:0060670","GO:1990051","GO:0046328","GO:0010863","GO:0000147","GO:0043547","GO:0045056","GO:1900042","GO:1904427","GO:0016477","GO:0060065","GO:1990441","GO:0021816","GO:0050798","GO:0072675","GO:0048011","GO:0048013","GO:0036493","GO:0007229","GO:0030702","GO:1905664","GO:0032005","GO:0051127","GO:0045737","GO:0060368","GO:0072584","GO:0032959","GO:0010641","GO:0071963","GO:0009395","GO:0071803","GO:0006348","GO:0038083","GO:1900029","GO:0002344","GO:0036120","GO:0060444","GO:0001865","GO:1903348","GO:0051017","GO:0051016","GO:0070358","GO:1903912","GO:0090135","GO:0044379","GO:0070836","GO:0010324","GO:0071560","GO:0097320","GO:0051902","GO:0002333","GO:0086098","GO:0031139","GO:0050865","GO:0034136","GO:0030035","GO:0022407","GO:0030838","GO:2000769","GO:1904703","GO:0070668","GO:0050852","GO:0050853","GO:0045087","GO:0006915","GO:0032911","GO:0032633","GO:0046580","GO:0060335","GO:0098761","GO:0010954","GO:2001286","GO:0021587","GO:0071300","GO:0002250","GO:0002316","GO:0045806","GO:0046718","GO:0006313","GO:0075713","GO:0015074","GO:0051301","GO:0007059","GO:0007049"]}],"graph":[["XP_008192389.2","NP_001035796.1",0.808],["XP_008192389.2","XP_064211184.1",0.511],["XP_008192389.2","XP_064214101.1",0.68],["XP_008192389.2","XP_064214556.1",0.85],["XP_008192389.2","XP_064214981.1",0.566],["XP_008192389.2","XP_064215705.1",0.728],["XP_008192389.2","XP_971585.2",0.702],["XP_008192389.2","XP_973632.1",0.857],["XP_008192389.2","XP_973868.2",0.508],["XP_064214981.1","NP_001035796.1",0.606],["XP_064214981.1","NP_001280508.1",0.872],["XP_064214981.1","XP_008196113.1",0.692],["XP_064214981.1","XP_064211141.1",0.669],["XP_064214981.1","XP_064211184.1",0.696],["XP_064214981.1","XP_064211278.1",0.677],["XP_064214981.1","XP_064214101.1",0.688],["XP_064214981.1","XP_064214556.1",0.828],["XP_064214981.1","XP_064215705.1",0.757],["XP_064214981.1","XP_971585.2",0.847],["XP_064214981.1","XP_973632.1",0.929],["XP_064214981.1","XP_973868.2",0.713],["XP_971585.2","NP_001035796.1",0.546],["XP_971585.2","NP_001280508.1",0.729],["XP_971585.2","XP_008196113.1",0.532],["XP_971585.2","XP_064211141.1",0.699],["XP_971585.2","XP_064211278.1",0.503],["XP_971585.2","XP_064214101.1",0.686],["XP_971585.2","XP_064214556.1",0.696],["XP_971585.2","XP_064215705.1",0.659],["XP_971585.2","XP_973632.1",0.837],["XP_971585.2","XP_973868.2",0.67],["XP_064211141.1","NP_001035796.1",0.723],["XP_064211141.1","NP_001280508.1",0.768],["XP_064211141.1","XP_064211184.1",0.733],["XP_064211141.1","XP_064211278.1",0.646],["XP_064211141.1","XP_064214101.1",0.707],["XP_064211141.1","XP_064214556.1",0.84],["XP_064211141.1","XP_064215705.1",0.795],["XP_064211141.1","XP_973632.1",0.872],["XP_064211141.1","XP_973868.2",0.739],["XP_064211184.1","XP_064214101.1",0.746],["XP_064211184.1","XP_064214556.1",0.67],["XP_064214101.1","NP_001035796.1",0.672],["XP_064214101.1","NP_001280508.1",0.778],["XP_064214101.1","XP_008196113.1",0.693],["XP_064214101.1","XP_064211278.1",0.784],["XP_064214101.1","XP_973632.1",0.822],["XP_064214101.1","XP_973868.2",0.751],["XP_064214101.1","XP_064214556.1",0.851],["XP_064214101.1","XP_064215705.1",0.753],["XP_973632.1","NP_001280508.1",0.724],["XP_973632.1","XP_008196113.1",0.623],["XP_973632.1","XP_064211278.1",0.569],["XP_973632.1","XP_064214556.1",0.92],["XP_973632.1","XP_064215705.1",0.863],["XP_973632.1","XP_973868.2",0.696],["NP_001280508.1","NP_001035796.1",0.659],["NP_001280508.1","XP_064214556.1",0.793],["NP_001280508.1","XP_064215705.1",0.603],["NP_001280508.1","XP_973868.2",0.767],["NP_001035796.1","XP_064214556.1",0.755],["NP_001035796.1","XP_064215705.1",0.756],["NP_001035796.1","XP_973868.2",0.615],["XP_064211278.1","XP_064214556.1",0.668],["XP_064211278.1","XP_064215705.1",0.512],["XP_064211278.1","XP_973868.2",0.533],["XP_973868.2","XP_008196113.1",0.524],["XP_973868.2","XP_064214556.1",0.852],["XP_973868.2","XP_064215705.1",0.808],["XP_064214556.1","XP_008196113.1",0.559],["XP_064214556.1","XP_064215705.1",0.882]],"all_go_terms":{"GO:0006954":1,"GO:0042148":1,"GO:1904631":1,"GO:0072757":1,"GO:0007127":1,"GO:0001932":1,"GO:0061674":1,"GO:0006303":1,"GO:0009432":1,"GO:0007568":2,"GO:0016446":2,"GO:0045003":1,"GO:0072711":1,"GO:0006290":1,"GO:0006288":1,"GO:0071707":1,"GO:0032508":1,"GO:0010332":1,"GO:0016579":1,"GO:1990414":1,"GO:0010165":1,"GO:0000732":1,"GO:0071480":1,"GO:1990426":1,"GO:0009636":1,"GO:0048872":1,"GO:0008630":1,"GO:0048536":1,"GO:0048535":1,"GO:0007131":1,"GO:0006287":1,"GO:0051402":1,"GO:0006297":2,"GO:0006412":2,"GO:0055093":1,"GO:0007435":1,"GO:0006286":2,"GO:0051106":1,"GO:0072719":1,"GO:0006284":3,"GO:0000730":1,"GO:0006260":7,"GO:0045471":1,"GO:1990506":1,"GO:0071897":1,"GO:0007571":1,"GO:1904754":1,"GO:0015074":8,"GO:0039651":5,"GO:0043249":1,"GO:0060729":1,"GO:0070200":1,"GO:1904173":1,"GO:0046326":1,"GO:0006310":5,"GO:1904751":1,"GO:0042635":1,"GO:1902895":1,"GO:0030177":1,"GO:0046718":6,"GO:1903620":1,"GO:0006278":5,"GO:0030422":1,"GO:1903704":5,"GO:2001240":1,"GO:0032092":1,"GO:0010073":1,"GO:2000648":1,"GO:0051000":1,"GO:2000773":1,"GO:0022616":1,"GO:0071456":1,"GO:0007004":1,"GO:0090399":1,"GO:0075713":6,"GO:0010449":1,"GO:0075732":5,"GO:0042276":1,"GO:0006261":1,"GO:0071494":1,"GO:0070987":1,"GO:0000447":1,"GO:0042254":1,"GO:0006313":3,"GO:0014912":1,"GO:0006915":2,"GO:0003335":1,"GO:2001153":1,"GO:0070301":1,"GO:0042493":1,"GO:0071320":1,"GO:1900087":1,"GO:0006308":1,"GO:0090502":1,"GO:0071375":1,"GO:0043488":1,"GO:1903507":1,"GO:2000466":1,"GO:0046856":1,"GO:0044179":1,"GO:0080111":1,"GO:2000327":1,"GO:0045454":1,"GO:0001302":1,"GO:0071140":1,"GO:0045876":1,"GO:0090267":1,"GO:0002455":1,"GO:0006295":1,"GO:0031292":1,"GO:1903469":1,"GO:0007613":1,"GO:0000734":1,"GO:0006289":1,"GO:0035753":1,"GO:0045190":1,"GO:0097113":1,"GO:0050865":1,"GO:0032959":1,"GO:0045806":1,"GO:0010954":1,"GO:1903898":1,"GO:0000147":1,"GO:0014911":1,"GO:1903676":1,"GO:0009952":1,"GO:0008286":1,"GO:0070667":1,"GO:0071800":1,"GO:0045056":1,"GO:0097117":1,"GO:0031666":1,"GO:0051282":1,"GO:1903760":1,"GO:0070358":1,"GO:0072675":1,"GO:0060292":1,"GO:1903348":1,"GO:0035023":1,"GO:0060017":1,"GO:0051835":1,"GO:0071625":1,"GO:1904427":1,"GO:0051127":1,"GO:1900275":1,"GO:0050853":1,"GO:1990314":1,"GO:0007264":1,"GO:0010324":1,"GO:0035020":1,"GO:0030890":1,"GO:0071963":1,"GO:0009395":1,"GO:0051666":1,"GO:0030032":1,"GO:2000394":1,"GO:1904424":1,"GO:0006909":1,"GO:1902237":1,"GO:0060997":1,"GO:0007015":1,"GO:0061847":1,"GO:1990090":1,"GO:0071803":1,"GO:1990051":1,"GO:0006348":1,"GO:0010863":1,"GO:1900042":1,"GO:0051301":1,"GO:0051017":1,"GO:0010641":1,"GO:1900044":1,"GO:0009887":1,"GO:0090557":1,"GO:0016191":1,"GO:0072584":1,"GO:1904703":1,"GO:0001568":1,"GO:0043552":1,"GO:0060065":1,"GO:0051044":1,"GO:0048538":1,"GO:0002774":1,"GO:1902951":1,"GO:0042997":1,"GO:0090162":1,"GO:2000769":1,"GO:0097107":1,"GO:0045737":1,"GO:0050731":1,"GO:0002344":1,"GO:0046580":1,"GO:2001286":1,"GO:0043547":1,"GO:0051968":1,"GO:0043652":1,"GO:1900026":1,"GO:0010923":1,"GO:0048008":1,"GO:0032005":1,"GO:1905664":1,"GO:0002051":1,"GO:0086098":1,"GO:2000822":1,"GO:0002316":1,"GO:0035156":1,"GO:0097114":1,"GO:0061462":1,"GO:0032287":1,"GO:1902498":1,"GO:2000821":1,"GO:0070668":1,"GO:0048011":1,"GO:1904717":1,"GO:0046847":1,"GO:1903286":1,"GO:0060988":1,"GO:2001205":1,"GO:1903753":1,"GO:0035750":1,"GO:0002333":1,"GO:0034136":1,"GO:0044855":1,"GO:0051902":1,"GO:0032633":1,"GO:1903356":1,"GO:0045087":1,"GO:0032911":1,"GO:0036493":1,"GO:0016477":1,"GO:0051016":1,"GO:0007059":1,"GO:1904179":1,"GO:0002250":1,"GO:0007507":1,"GO:0090263":1,"GO:0031139":1,"GO:0051660":1,"GO:0071732":1,"GO:0030041":1,"GO:0001878":1,"GO:1990441":1,"GO:0060444":1,"GO:0048170":1,"GO:1904888":1,"GO:0097320":1,"GO:0010976":1,"GO:0050894":1,"GO:0036120":1,"GO:0071560":1,"GO:0007229":1,"GO:2000969":1,"GO:0071847":1,"GO:0033146":1,"GO:0001865":1,"GO:1903912":1,"GO:0038083":1,"GO:0090135":1,"GO:0060348":1,"GO:0046328":1,"GO:1904528":1,"GO:0045953":1,"GO:0070830":1,"GO:0060124":1,"GO:0045794":1,"GO:1900273":1,"GO:0050852":1,"GO:0021816":1,"GO:0035176":1,"GO:1903764":1,"GO:0050798":1,"GO:0007049":1,"GO:0071896":1,"GO:1990859":1,"GO:0030035":1,"GO:0071300":1,"GO:0098761":1,"GO:1900029":1,"GO:0070836":1,"GO:0035728":1,"GO:0007173":1,"GO:0060335":1,"GO:1901076":1,"GO:0021773":1,"GO:0021587":1,"GO:0044379":1,"GO:0060291":1,"GO:0034446":1,"GO:0034260":1,"GO:0030702":1,"GO:0060022":1,"GO:2000463":1,"GO:1904531":1,"GO:0060368":1,"GO:0060670":1,"GO:0090110":1,"GO:0060378":1,"GO:0022407":1,"GO:0030838":1,"GO:0048013":1,"GO:0016560":1,"GO:0001771":1},"recipe_readded":[]}