{"hash":"1423992778141748098","title":"ERAD-Linked Protein Quality Control","description":"This cluster centers on degradation and quality-control pathways, highlighted by ubiquitin-dependent ERAD, unfolded protein response maintenance, and related processing (deglycosylation, sumoylation). Additional terms on vesicle formation, endocytosis, and mitophagy reinforce a theme of protein turnover and trafficking quality control. Some terms (e.g., nucleotide-excision repair) may reflect noise or broader cellular stress roles, but the dominant signal points to ER-associated quality control and turnover.","confidence":"Medium","size":25,"edges":300,"triangles":2300,"max_degree":24,"top_function":null,"members":[{"accession":"XP_007491648.1","go_terms":["GO:0070242","GO:0043065","GO:1902511","GO:0035634","GO:0097194","GO:0090200","GO:0030263","GO:0019915","GO:0097202","GO:0006309","GO:0010890","GO:0032720","GO:0045476","GO:0001659","GO:0030512","GO:0050710","GO:0050995"]},{"accession":"XP_007491966.2","go_terms":["GO:0099641","GO:0071480","GO:0032387","GO:0050821","GO:0032355","GO:0009644","GO:0030308","GO:0032463","GO:2000378","GO:0070309","GO:0006936","GO:0070141","GO:0031109","GO:0009408","GO:0007568","GO:0042542","GO:1900034","GO:0051403","GO:1905907","GO:0030307","GO:0002088","GO:0001666","GO:0007021","GO:0051260","GO:0045766","GO:0060561","GO:0006937","GO:0048596","GO:0007525","GO:0010667","GO:0043154"]},{"accession":"XP_001379043.1","go_terms":["GO:0034727","GO:0000422","GO:0061723","GO:0006501","GO:0035096","GO:0044805","GO:0032258","GO:0000045","GO:0000226","GO:0034198","GO:0010940","GO:0010040","GO:0034629","GO:0040024","GO:0008625","GO:0006888","GO:0097352","GO:0071211","GO:0070301","GO:0010288","GO:0061709","GO:0006915","GO:0043278","GO:0071280","GO:0070257"]},{"accession":"XP_056673298.1","go_terms":["GO:0034389","GO:0007253","GO:0031134","GO:1904293","GO:0031468","GO:0002814","GO:2000157","GO:0030433","GO:0061060","GO:0008219","GO:1903094","GO:0046324"]},{"accession":"XP_056677040.1","go_terms":["GO:0000423","GO:1901097","GO:0033132","GO:1902236","GO:1901340","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:0035973","GO:1901799","GO:1902283","GO:0016579","GO:1904378","GO:0030474","GO:0017085","GO:1903071","GO:0006289","GO:0051865","GO:0034140","GO:0030433","GO:0016925","GO:1905366","GO:0000028","GO:0010636","GO:0010637","GO:0000753","GO:0071816","GO:0070842","GO:0097237","GO:1900186","GO:1904021","GO:0006517","GO:1904049","GO:0006412"]},{"accession":"XP_056681315.1","go_terms":["GO:0099641","GO:0071480","GO:0032387","GO:0050821","GO:0032355","GO:0009644","GO:0030308","GO:0032463","GO:2000378","GO:0070309","GO:0006936","GO:0070141","GO:0031109","GO:0009408","GO:0007568","GO:0042542","GO:1900034","GO:0051403","GO:1905907","GO:0030307","GO:0002088","GO:0001666","GO:0007021","GO:0051260","GO:0045766","GO:0060561","GO:0006937","GO:0048596","GO:0007525","GO:0010667","GO:0043154"]},{"accession":"XP_001364319.4","go_terms":["GO:1903061","GO:0061321","GO:0090083","GO:0032435","GO:0090367","GO:0071260","GO:0097192","GO:0010664","GO:0097201","GO:0008625","GO:0051496","GO:0010763","GO:1902176","GO:0031397","GO:2001145","GO:0010228","GO:0042993","GO:0071364","GO:0097178","GO:0046827","GO:0061084","GO:1903215","GO:0000423","GO:1901097","GO:0033132","GO:1902236","GO:1901340","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:0035973","GO:1901799","GO:1902283","GO:0016579","GO:1904378","GO:0030474","GO:0017085","GO:1903071","GO:0006289","GO:0051865","GO:0034140","GO:0030433","GO:0016925","GO:1905366","GO:0000028","GO:0010636","GO:0010637","GO:0000753","GO:0071816","GO:0070842","GO:0097237","GO:1900186","GO:1904021","GO:0006517","GO:1904049","GO:0006412"]},{"accession":"XP_001366044.1","go_terms":["GO:0000423","GO:1901097","GO:0033132","GO:1902236","GO:1901340","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:0035973","GO:1901799","GO:1902283","GO:0016579","GO:1904378","GO:0030474","GO:0017085","GO:1903071","GO:0006289","GO:0051865","GO:0034140","GO:0030433","GO:0016925","GO:1905366","GO:0000028","GO:0010636","GO:0010637","GO:0000753","GO:0071816","GO:0070842","GO:0097237","GO:1900186","GO:1904021","GO:0006517","GO:1904049","GO:0006412","GO:0019731","GO:0002227"]},{"accession":"XP_001370360.2","go_terms":["GO:0034727","GO:0000422","GO:0061723","GO:0006501","GO:0035096","GO:0044805","GO:0032258","GO:0000045","GO:0000226","GO:0034198","GO:0010940","GO:0010040","GO:0034629","GO:0040024","GO:0008625","GO:0006888","GO:0097352","GO:0071211","GO:0070301","GO:0010288","GO:0061709","GO:0006915","GO:0043278","GO:0071280","GO:0070257"]},{"accession":"XP_001370505.3","go_terms":["GO:0032436","GO:0070911","GO:0034126","GO:0090204","GO:0010286","GO:1901896","GO:0071276","GO:0043392","GO:0060334","GO:0051572","GO:0016925","GO:0043433","GO:0035186","GO:0086004","GO:0030578","GO:1902260","GO:0045944","GO:0045759","GO:0000423","GO:1901097","GO:0033132","GO:1902236","GO:1901340","GO:1903265","GO:0021888","GO:0014070","GO:0010216","GO:0045648","GO:0002109","GO:0006357","GO:0035973","GO:1901799","GO:1902283","GO:0016579","GO:1904378","GO:0030474","GO:0017085","GO:1903071","GO:0006289","GO:0051865","GO:0034140","GO:0030433","GO:1905366","GO:0000028","GO:0010636","GO:0010637","GO:0000753","GO:0071816","GO:0070842","GO:0097237","GO:1900186","GO:1904021","GO:0006517","GO:1904049","GO:0006412"]},{"accession":"XP_001372717.4","go_terms":["GO:0032436","GO:0070911","GO:0034126","GO:0090204","GO:0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