{"hash":"966002974109368206","title":"LPS/TLR4 innate immune signaling","description":"The top GO terms cluster around detection of lipopolysaccharide and signaling via the Toll-like receptor 4 pathway, including positive regulation of LPS signaling and necroptotic process, which together point to an innate immune response to Gram-negative bacteria. Some terms related to cholesterol metabolism/transport may reflect membrane-related aspects of signaling, while a couple (learning/memory, ecdysteroid biosynthesis) appear as noise or broader biological contexts. Overall, the dominant theme is LPS-induced innate immune signaling, with lipid processes as a secondary link.","confidence":"Medium","size":16,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_001319038.1","go_terms":[]},{"accession":"XP_001313438.1","go_terms":[]},{"accession":"XP_001317859.1","go_terms":["GO:0032760","GO:0070266","GO:0071222","GO:0034142","GO:0034128","GO:0045087","GO:0009313","GO:0007611","GO:0006954","GO:0019915","GO:0045456","GO:0042632","GO:0061057","GO:0006689","GO:0032497","GO:0050885","GO:0051345","GO:0031663","GO:0031666","GO:0009615","GO:0033344","GO:0032367","GO:0008203"]},{"accession":"XP_001318023.1","go_terms":["GO:0000470","GO:0006417","GO:0006412"]},{"accession":"XP_001322344.1","go_terms":[]},{"accession":"XP_001325287.1","go_terms":[]},{"accession":"XP_001330771.1","go_terms":[]},{"accession":"XP_001581420.1","go_terms":[]},{"accession":"XP_001582183.1","go_terms":[]},{"accession":"XP_051089182.1","go_terms":[]},{"accession":"XP_051097478.1","go_terms":["GO:0006314"]},{"accession":"XP_051100461.1","go_terms":[]},{"accession":"XP_051109487.1","go_terms":[]},{"accession":"XP_001296677.2","go_terms":[]},{"accession":"XP_001296842.1","go_terms":[]},{"accession":"XP_001297173.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0031663":1,"GO:0007611":1,"GO:0009313":1,"GO:0070266":1,"GO:0008203":1,"GO:0032497":1,"GO:0045456":1,"GO:0034142":1,"GO:0031666":1,"GO:0032367":1,"GO:0033344":1,"GO:0034128":1,"GO:0009615":1,"GO:0006689":1,"GO:0050885":1,"GO:0042632":1,"GO:0051345":1,"GO:0071222":1,"GO:0061057":1,"GO:0019915":1,"GO:0032760":1,"GO:0045087":1,"GO:0006954":1,"GO:0006417":1,"GO:0000470":1,"GO:0006412":1,"GO:0006314":1},"recipe_readded":["XP_001582336.1"]}