{"hash":"435816071734657470","title":"ER stress response and MHC class I antigen presentation","description":"The dominant GO terms cluster around the endoplasmic reticulum unfolded protein response and protein folding, and include peptide antigen assembly with MHC class I, suggesting a module linking ER quality control to antigen presentation and immune signaling. Additional terms such as dendritic cell chemotaxis and non-canonical NF-kappaB signaling support an immune-related context, while some other terms may reflect broader trafficking or development roles. Overall, the core theme is ER-associated protein folding with antigen processing and presentation.","confidence":"Medium","size":9,"edges":31,"triangles":53,"max_degree":8,"top_function":"protein folding","members":[{"accession":"XP_001582432.1","go_terms":["GO:0050766","GO:0033144","GO:0006457","GO:0030968","GO:0002502","GO:1900026","GO:2000510","GO:0090398","GO:0010204","GO:0048916","GO:1901224","GO:0007339","GO:0048387","GO:0048488","GO:0071157"]},{"accession":"XP_001319610.1","go_terms":["GO:0050766","GO:0033144","GO:0006457","GO:0030968","GO:0002502","GO:1900026","GO:2000510","GO:0090398","GO:0010204","GO:0048916","GO:1901224","GO:0007339","GO:0048387","GO:0048488","GO:0071157"]},{"accession":"XP_001325490.1","go_terms":["GO:0050766","GO:0033144","GO:0006457","GO:0030968","GO:0002502","GO:1900026","GO:2000510","GO:0090398","GO:0010204","GO:0048916","GO:1901224","GO:0007339","GO:0048387","GO:0048488","GO:0071157"]},{"accession":"XP_001306450.1","go_terms":[]},{"accession":"XP_001299721.1","go_terms":["GO:0050766","GO:0033144","GO:0006457","GO:0030968","GO:0002502","GO:1900026","GO:2000510","GO:0090398","GO:0010204","GO:0048916","GO:1901224","GO:0007339","GO:0048387","GO:0048488","GO:0071157"]},{"accession":"XP_001310397.1","go_terms":["GO:2000253","GO:0018095","GO:0060296"]},{"accession":"XP_001317069.1","go_terms":["GO:0007100","GO:0036523","GO:0052014","GO:0007155","GO:1902769"]},{"accession":"XP_001579557.1","go_terms":["GO:0030420","GO:0019538","GO:0006289","GO:0006355","GO:0006351","GO:0009432"]},{"accession":"XP_001325432.1","go_terms":[]}],"graph":[["XP_001325432.1","XP_001310397.1",0.928],["XP_001325432.1","XP_001317069.1",0.755],["XP_001325432.1","XP_001579557.1",0.851],["XP_001325432.1","XP_001299721.1",0.582],["XP_001325432.1","XP_001306450.1",0.754],["XP_001299721.1","XP_001306450.1",0.909],["XP_001299721.1","XP_001310397.1",0.572],["XP_001299721.1","XP_001325490.1",0.944],["XP_001299721.1","XP_001319610.1",0.896],["XP_001299721.1","XP_001317069.1",0.887],["XP_001299721.1","XP_001582432.1",0.941],["XP_001299721.1","XP_001579557.1",0.869],["XP_001582432.1","XP_001310397.1",0.769],["XP_001582432.1","XP_001317069.1",0.882],["XP_001582432.1","XP_001319610.1",0.916],["XP_001582432.1","XP_001325490.1",0.953],["XP_001582432.1","XP_001579557.1",0.896],["XP_001582432.1","XP_001306450.1",0.917],["XP_001325490.1","XP_001310397.1",0.698],["XP_001325490.1","XP_001317069.1",0.854],["XP_001325490.1","XP_001319610.1",0.905],["XP_001325490.1","XP_001579557.1",0.822],["XP_001325490.1","XP_001306450.1",0.911],["XP_001319610.1","XP_001310397.1",0.517],["XP_001319610.1","XP_001317069.1",0.912],["XP_001319610.1","XP_001579557.1",0.823],["XP_001319610.1","XP_001306450.1",0.936],["XP_001306450.1","XP_001317069.1",0.833],["XP_001306450.1","XP_001579557.1",0.767],["XP_001310397.1","XP_001317069.1",0.556],["XP_001317069.1","XP_001579557.1",0.782]],"all_go_terms":{"GO:0030968":4,"GO:0006457":4,"GO:0033144":4,"GO:1901224":4,"GO:0048488":4,"GO:0048916":4,"GO:2000510":4,"GO:0071157":4,"GO:0048387":4,"GO:0002502":4,"GO:0090398":4,"GO:0007339":4,"GO:0050766":4,"GO:1900026":4,"GO:0010204":4,"GO:2000253":1,"GO:0060296":1,"GO:0018095":1,"GO:0007100":1,"GO:0007155":1,"GO:0052014":1,"GO:1902769":1,"GO:0036523":1,"GO:0006355":1,"GO:0019538":1,"GO:0006351":1,"GO:0009432":1,"GO:0030420":1,"GO:0006289":1},"recipe_readded":[]}