{"hash":"21283962106246185","title":"Cytoskeletal remodeling and membrane dynamics","description":"The cluster is most coherently tied by GO terms pointing to actin-driven protrusions and membrane remodeling: filopodium assembly, plasma membrane tubulation, and small GTPase-mediated signaling are classic indicators of cytoskeletal dynamics and membrane shaping. Additionally, positive regulation of neuron projection development aligns with cytoskeletal changes required for neurite outgrowth. A few other terms (e.g., peroxisome docking, translational initiation, apoptotic process) appear less central to this core theme, but do not override the predominant signal toward cytoskeletal/membrane remodeling functions.","confidence":"Medium","size":19,"edges":107,"triangles":232,"max_degree":16,"top_function":null,"members":[{"accession":"XP_001319689.1","go_terms":[]},{"accession":"XP_001319987.1","go_terms":[]},{"accession":"XP_001329311.1","go_terms":[]},{"accession":"XP_001579156.1","go_terms":["GO:0006909","GO:0034446","GO:0051282","GO:1903676","GO:0030041","GO:0051044","GO:0044855","GO:0045953","GO:1902951","GO:0060017","GO:0033146","GO:0070667","GO:1904531","GO:0007264","GO:0007173","GO:0010976","GO:0051666","GO:0042997","GO:1900275","GO:0016191","GO:0002774","GO:0050731","GO:0060988","GO:0016560","GO:0046847","GO:1903898","GO:0090263","GO:1904528","GO:1902237","GO:0048008","GO:0060670","GO:1990051","GO:0046328","GO:0010863","GO:0061847","GO:0000147","GO:0043547","GO:0045056","GO:1900042","GO:1904427","GO:0016477","GO:0060065","GO:1990441","GO:0021816","GO:0050798","GO:0060378","GO:0072675","GO:0048011","GO:0048013","GO:0036493","GO:0043552","GO:0009952","GO:0007229","GO:0030702","GO:0002051","GO:1905664","GO:0032005","GO:0051127","GO:0045737","GO:0060368","GO:0072584","GO:0032959","GO:0035020","GO:0035023","GO:0010641","GO:0071963","GO:0009395","GO:0071803","GO:0071800","GO:0006348","GO:0038083","GO:1900029","GO:1900026","GO:0002344","GO:0036120","GO:0014911","GO:0060444","GO:0001865","GO:0008286","GO:0007507","GO:1903348","GO:0051017","GO:0051016","GO:0070358","GO:1903912","GO:0090135","GO:0044379","GO:0070836","GO:0010324","GO:0071560","GO:0097320","GO:0051902","GO:0002333","GO:0086098","GO:0031139","GO:0050865","GO:0030032","GO:0034136","GO:0030035","GO:0060348","GO:0022407","GO:1990859","GO:2000821","GO:0030838","GO:2000769","GO:0048538","GO:1904703","GO:0070668","GO:1904179","GO:0050852","GO:0050853","GO:0045087","GO:0006915","GO:0032911","GO:0032633","GO:0046580","GO:0060335","GO:0098761","GO:0010954","GO:2001286","GO:0021587","GO:0071732","GO:0071300","GO:0002250","GO:0002316","GO:0045806"]},{"accession":"XP_001582881.1","go_terms":[]},{"accession":"XP_001583499.1","go_terms":["GO:0010446"]},{"accession":"XP_001583594.1","go_terms":[]},{"accession":"XP_051076929.1","go_terms":[]},{"accession":"XP_051091020.1","go_terms":[]},{"accession":"XP_051103741.1","go_terms":[]},{"accession":"XP_001300566.2","go_terms":[]},{"accession":"XP_001302360.1","go_terms":[]},{"accession":"XP_001306304.1","go_terms":[]},{"accession":"XP_001581964.1","go_terms":[]},{"accession":"XP_051101851.1","go_terms":[]},{"accession":"XP_001581492.1","go_terms":[]},{"accession":"XP_001319763.1","go_terms":[]},{"accession":"XP_001323443.1","go_terms":[]},{"accession":"XP_001301011.1","go_terms":[]}],"graph":[["XP_001302360.1","XP_001300566.2",0.981],["XP_001302360.1","XP_001301011.1",0.922],["XP_001302360.1","XP_001319689.1",0.921],["XP_001302360.1","XP_001319763.1",0.943],["XP_001302360.1","XP_001329311.1",0.981],["XP_001302360.1","XP_001581964.1",0.821],["XP_001302360.1","XP_001582881.1",0.973],["XP_001302360.1","XP_001583499.1",0.933],["XP_001302360.1","XP_001583594.1",0.746],["XP_001302360.1","XP_051076929.1",0.526],["XP_001302360.1","XP_051091020.1",0.654],["XP_001302360.1","XP_051103741.1",0.982],["XP_001581964.1","XP_001319689.1",0.935],["XP_001581964.1","XP_001319763.1",0.938],["XP_001581964.1","XP_001319987.1",0.638],["XP_001581964.1","XP_001323443.1",0.858],["XP_001581964.1","XP_001329311.1",0.963],["XP_001581964.1","XP_001581492.1",0.859],["XP_001581964.1","XP_001583499.1",0.858],["XP_001581964.1","XP_001301011.1",0.858],["XP_001581964.1","XP_001306304.1",0.86],["XP_001582881.1","XP_001319689.1",0.893],["XP_001582881.1","XP_001319763.1",0.935],["XP_001582881.1","XP_001319987.1",0.938],["XP_001582881.1","XP_001329311.1",0.961],["XP_001582881.1","XP_001581492.1",0.659],["XP_001582881.1","XP_001583499.1",0.795],["XP_001582881.1","XP_001301011.1",0.96],["XP_001582881.1","XP_001306304.1",0.618],["XP_001319763.1","XP_001323443.1",0.515],["XP_001319763.1","XP_001319689.1",0.51],["XP_001319763.1","XP_001319987.1",0.909],["XP_001319763.1","XP_001579156.1",0.938],["XP_001319763.1","XP_051101851.1",0.938],["XP_001319763.1","XP_051103741.1",0.933],["XP_001319763.1","XP_051091020.1",0.934],["XP_001319763.1","XP_051076929.1",0.937],["XP_001319763.1","XP_001583594.1",0.937],["XP_001319763.1","XP_001300566.2",0.934],["XP_001319763.1","XP_001306304.1",0.984],["XP_001583499.1","XP_001319689.1",0.689],["XP_001583499.1","XP_001319987.1",0.704],["XP_001583499.1","XP_001323443.1",0.627],["XP_001583499.1","XP_001579156.1",0.958],["XP_001583499.1","XP_001581492.1",0.701],["XP_001583499.1","XP_001583594.1",0.857],["XP_001583499.1","XP_051091020.1",0.853],["XP_001583499.1","XP_051103741.1",0.85],["XP_001583499.1","XP_001300566.2",0.852],["XP_001583499.1","XP_001301011.1",0.871],["XP_001583499.1","XP_001306304.1",0.851],["XP_001319689.1","XP_001319987.1",0.962],["XP_001319689.1","XP_001581492.1",0.751],["XP_001319689.1","XP_001579156.1",0.962],["XP_001319689.1","XP_001329311.1",0.5],["XP_001319689.1","XP_051101851.1",0.935],["XP_001319689.1","XP_051103741.1",0.844],["XP_001319689.1","XP_051091020.1",0.847],["XP_001319689.1","XP_051076929.1",0.93],["XP_001319689.1","XP_001583594.1",0.933],["XP_001319689.1","XP_001300566.2",0.844],["XP_001319689.1","XP_001306304.1",0.977],["XP_051091020.1","XP_001319987.1",0.857],["XP_051091020.1","XP_001323443.1",0.85],["XP_051091020.1","XP_001329311.1",0.96],["XP_051091020.1","XP_001579156.1",0.856],["XP_051091020.1","XP_001301011.1",0.951],["XP_051091020.1","XP_001306304.1",0.633],["XP_001581492.1","XP_001329311.1",0.963],["XP_001581492.1","XP_051103741.1",0.936],["XP_001581492.1","XP_001300566.2",0.889],["XP_001581492.1","XP_001301011.1",0.859],["XP_001319987.1","XP_051103741.1",0.982],["XP_001319987.1","XP_001300566.2",0.981],["XP_001319987.1","XP_001301011.1",0.885],["XP_001319987.1","XP_001306304.1",0.776],["XP_001579156.1","XP_001323443.1",0.502],["XP_001579156.1","XP_001329311.1",0.974],["XP_001579156.1","XP_051103741.1",0.855],["XP_001579156.1","XP_001300566.2",0.855],["XP_001579156.1","XP_001301011.1",0.882],["XP_001579156.1","XP_001306304.1",0.711],["XP_001300566.2","XP_001301011.1",0.863],["XP_001300566.2","XP_001306304.1",0.936],["XP_001300566.2","XP_001323443.1",0.849],["XP_001300566.2","XP_001329311.1",0.959],["XP_001329311.1","XP_001323443.1",0.885],["XP_001329311.1","XP_051101851.1",0.963],["XP_001329311.1","XP_051103741.1",0.921],["XP_001329311.1","XP_051076929.1",0.962],["XP_001329311.1","XP_001583594.1",0.962],["XP_001329311.1","XP_001306304.1",0.984],["XP_001306304.1","XP_001301011.1",0.887],["XP_001306304.1","XP_001323443.1",0.896],["XP_001306304.1","XP_001583594.1",0.962],["XP_001306304.1","XP_051076929.1",0.859],["XP_001306304.1","XP_051101851.1",0.69],["XP_001306304.1","XP_051103741.1",0.935],["XP_001323443.1","XP_001583594.1",0.855],["XP_001323443.1","XP_051076929.1",0.856],["XP_001323443.1","XP_051101851.1",0.858],["XP_001323443.1","XP_051103741.1",0.849],["XP_001323443.1","XP_001301011.1",0.741],["XP_001301011.1","XP_001583594.1",0.962],["XP_001301011.1","XP_051076929.1",0.858],["XP_001301011.1","XP_051101851.1",0.86],["XP_001301011.1","XP_051103741.1",0.95]],"all_go_terms":{"GO:0046847":1,"GO:0007264":1,"GO:0032005":1,"GO:0031139":1,"GO:0006915":1,"GO:0009395":1,"GO:0016560":1,"GO:0097320":1,"GO:1903676":1,"GO:0010976":1,"GO:2000821":1,"GO:0071800":1,"GO:0014911":1,"GO:0048008":1,"GO:0035020":1,"GO:0051282":1,"GO:0051016":1,"GO:0048011":1,"GO:0043547":1,"GO:0010641":1,"GO:0032959":1,"GO:0071560":1,"GO:0038083":1,"GO:0044855":1,"GO:0060065":1,"GO:0060378":1,"GO:0044379":1,"GO:0072675":1,"GO:1902237":1,"GO:0030032":1,"GO:1990859":1,"GO:0050731":1,"GO:0050852":1,"GO:0002051":1,"GO:0002250":1,"GO:1904703":1,"GO:0070668":1,"GO:1905664":1,"GO:0050798":1,"GO:0010954":1,"GO:2001286":1,"GO:0022407":1,"GO:0010863":1,"GO:0072584":1,"GO:1904427":1,"GO:0046580":1,"GO:1900029":1,"GO:0060335":1,"GO:0021587":1,"GO:1904531":1,"GO:0016477":1,"GO:0071963":1,"GO:0030035":1,"GO:0000147":1,"GO:0061847":1,"GO:0060348":1,"GO:0060017":1,"GO:0001865":1,"GO:1903912":1,"GO:0042997":1,"GO:1990051":1,"GO:0048538":1,"GO:0045737":1,"GO:0006909":1,"GO:0051666":1,"GO:0070836":1,"GO:0051017":1,"GO:1903898":1,"GO:0070667":1,"GO:0002344":1,"GO:0048013":1,"GO:0030041":1,"GO:2000769":1,"GO:0045953":1,"GO:1904528":1,"GO:0043552":1,"GO:0034446":1,"GO:0034136":1,"GO:0002316":1,"GO:0046328":1,"GO:0051044":1,"GO:0035023":1,"GO:0010324":1,"GO:0007173":1,"GO:0007229":1,"GO:1904179":1,"GO:0036120":1,"GO:0086098":1,"GO:0071803":1,"GO:0090263":1,"GO:0060988":1,"GO:0009952":1,"GO:1990441":1,"GO:0050853":1,"GO:0016191":1,"GO:0036493":1,"GO:0021816":1,"GO:1903348":1,"GO:1902951":1,"GO:0060444":1,"GO:0032633":1,"GO:0045056":1,"GO:0033146":1,"GO:1900042":1,"GO:0008286":1,"GO:0030702":1,"GO:0090135":1,"GO:1900026":1,"GO:0060670":1,"GO:0051902":1,"GO:0045806":1,"GO:0006348":1,"GO:0098761":1,"GO:0032911":1,"GO:0002774":1,"GO:0002333":1,"GO:0051127":1,"GO:0050865":1,"GO:0030838":1,"GO:0071732":1,"GO:0060368":1,"GO:0070358":1,"GO:0071300":1,"GO:0045087":1,"GO:1900275":1,"GO:0007507":1,"GO:0010446":1},"recipe_readded":[]}