{"hash":"1949946062908605527","title":"Redox Homeostasis and Oxidative Stress Signaling","description":"This cluster is dominated by GO terms related to redox balance and oxidative stress responses (cell redox homeostasis, oxidation-reduction processes, hydrogen peroxide catabolic process, cellular oxidant detoxification). It also includes signaling context such as regulation of stress-activated MAPK cascade and NF-kappaB signaling, indicating a common theme around redox-regulated stress responses, despite a couple of outlier terms like erythrocyte homeostasis or gonad development. Overall, the redox-centric functions best unify the cluster.","confidence":"High","size":10,"edges":35,"triangles":54,"max_degree":9,"top_function":"extracellular matrix organization","members":[{"accession":"XP_001309666.1","go_terms":["GO:0008584","GO:0042744","GO:0007252","GO:0034101","GO:0018171","GO:2000255","GO:0070301","GO:0061407","GO:0032872","GO:0022417","GO:0045454","GO:0042345","GO:0042267","GO:0019471","GO:0007283","GO:0019430","GO:0030198","GO:0033195","GO:0017004","GO:0098869","GO:0042158","GO:0055114","GO:0030416"]},{"accession":"XP_001313356.1","go_terms":["GO:0008584","GO:0042744","GO:0007252","GO:0034101","GO:0018171","GO:2000255","GO:0070301","GO:0061407","GO:0032872","GO:0022417","GO:0045454","GO:0042345","GO:0042267","GO:0019471","GO:0007283","GO:0019430","GO:0030198","GO:0033195","GO:0017004","GO:0098869","GO:0042158","GO:0055114","GO:0030416"]},{"accession":"XP_001316602.1","go_terms":["GO:0008584","GO:0042744","GO:0007252","GO:0034101","GO:0018171","GO:2000255","GO:0070301","GO:0061407","GO:0032872","GO:0022417","GO:0045454","GO:0042345","GO:0042267","GO:0019471","GO:0007283","GO:0019430","GO:0030198","GO:0033195","GO:0017004","GO:0098869","GO:0042158","GO:0055114","GO:0030416"]},{"accession":"XP_001328156.1","go_terms":["GO:0017004","GO:0098869","GO:0045454","GO:0042158","GO:0055114","GO:0008584","GO:0042744","GO:0007252","GO:0034101","GO:0018171","GO:0070301","GO:2000255","GO:0032872","GO:0007283","GO:0030416","GO:0042345","GO:0042267","GO:0019471","GO:0022417","GO:0019430","GO:0030198"]},{"accession":"XP_001276890.1","go_terms":["GO:0006777","GO:0070329","GO:0019346","GO:0000087","GO:0035335","GO:0021510","GO:0018192","GO:0032447","GO:0030855","GO:2000220","GO:0006071","GO:0045454","GO:0002143"]},{"accession":"XP_001298652.1","go_terms":["GO:0008584","GO:0042744","GO:0007252","GO:0034101","GO:0018171","GO:2000255","GO:0070301","GO:0061407","GO:0032872","GO:0022417","GO:0045454","GO:0042345","GO:0042267","GO:0019471","GO:0007283","GO:0019430","GO:0030198","GO:0033195","GO:0017004","GO:0098869","GO:0042158","GO:0055114","GO:0030416"]},{"accession":"XP_001299092.1","go_terms":["GO:0008584","GO:0042744","GO:0007252","GO:0034101","GO:0018171","GO:2000255","GO:0070301","GO:0061407","GO:0032872","GO:0022417","GO:0045454","GO:0042345","GO:0042267","GO:0019471","GO:0007283","GO:0019430","GO:0030198","GO:0033195","GO:0017004","GO:0098869","GO:0042158","GO:0055114","GO:0030416"]},{"accession":"XP_001320753.1","go_terms":["GO:0017004","GO:0098869","GO:0045454","GO:0042158","GO:0055114","GO:0008584","GO:0042744","GO:0007252","GO:0034101","GO:0018171","GO:0070301","GO:2000255","GO:0032872","GO:0007283","GO:0030416","GO:0042345","GO:0042267","GO:0019471","GO:0022417","GO:0019430","GO:0030198"]},{"accession":"XP_001579115.1","go_terms":[]},{"accession":"XP_001312611.1","go_terms":[]}],"graph":[["XP_001579115.1","XP_001309666.1",0.985],["XP_001579115.1","XP_001312611.1",0.743],["XP_001579115.1","XP_001313356.1",0.857],["XP_001579115.1","XP_001316602.1",0.963],["XP_001579115.1","XP_001298652.1",0.973],["XP_001579115.1","XP_001299092.1",0.895],["XP_001313356.1","XP_001309666.1",0.961],["XP_001313356.1","XP_001312611.1",0.849],["XP_001313356.1","XP_001320753.1",0.83],["XP_001313356.1","XP_001328156.1",0.959],["XP_001313356.1","XP_001276890.1",0.686],["XP_001313356.1","XP_001299092.1",0.506],["XP_001316602.1","XP_001309666.1",0.957],["XP_001316602.1","XP_001312611.1",0.929],["XP_001316602.1","XP_001320753.1",0.919],["XP_001316602.1","XP_001328156.1",0.944],["XP_001316602.1","XP_001276890.1",0.542],["XP_001316602.1","XP_001298652.1",0.64],["XP_001312611.1","XP_001309666.1",0.942],["XP_001312611.1","XP_001320753.1",0.85],["XP_001312611.1","XP_001298652.1",0.929],["XP_001312611.1","XP_001299092.1",0.929],["XP_001276890.1","XP_001298652.1",0.685],["XP_001276890.1","XP_001309666.1",0.859],["XP_001276890.1","XP_001328156.1",0.861],["XP_001309666.1","XP_001320753.1",0.942],["XP_001309666.1","XP_001328156.1",0.941],["XP_001309666.1","XP_001298652.1",0.964],["XP_001309666.1","XP_001299092.1",0.944],["XP_001298652.1","XP_001299092.1",0.751],["XP_001298652.1","XP_001320753.1",0.855],["XP_001298652.1","XP_001328156.1",0.837],["XP_001328156.1","XP_001320753.1",0.933],["XP_001328156.1","XP_001299092.1",0.932],["XP_001299092.1","XP_001320753.1",0.914]],"all_go_terms":{"GO:0045454":8,"GO:0055114":7,"GO:0032872":7,"GO:0022417":7,"GO:0042345":7,"GO:0098869":7,"GO:0033195":5,"GO:0034101":7,"GO:0018171":7,"GO:0008584":7,"GO:0042744":7,"GO:0007252":7,"GO:0042267":7,"GO:0019471":7,"GO:0030198":7,"GO:0030416":7,"GO:2000255":7,"GO:0061407":5,"GO:0017004":7,"GO:0070301":7,"GO:0019430":7,"GO:0042158":7,"GO:0007283":7,"GO:0032447":1,"GO:0021510":1,"GO:0002143":1,"GO:0006777":1,"GO:0018192":1,"GO:2000220":1,"GO:0006071":1,"GO:0030855":1,"GO:0000087":1,"GO:0035335":1,"GO:0070329":1,"GO:0019346":1},"recipe_readded":[]}