{"hash":"1829566201700014267","title":"Endolysosomal trafficking and autophagy regulation","description":"The top GO terms cluster around endosomal sorting and degradation pathways: intralumenal vesicle formation, multivesicular body sorting, MVB-lysosome fusion, and protein transport to vacuoles/lysosomes, all pointing to endosome-to-lysosome trafficking. The inclusion of negative regulation of autophagosome assembly links autophagy to these trafficking processes. While there are a few disparate terms (e.g., mitotic chromosome condensation, follicle cell formation), the shared theme is intracellular vesicle trafficking toward degradation compartments and its regulation.","confidence":"High","size":4,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_001318183.1","go_terms":["GO:0007080","GO:0039702","GO:1902188","GO:1902187","GO:0030447","GO:0051301","GO:0090148","GO:1901673","GO:0036438","GO:0045053","GO:0043162","GO:0000920","GO:0019058","GO:0071454","GO:0071985","GO:1904669","GO:0043328","GO:2000641","GO:0036258","GO:0006915","GO:0006620","GO:0031468","GO:0061763","GO:0007076","GO:1903541","GO:1903723","GO:0010458","GO:0006997","GO:0007049","GO:0009838","GO:0030713","GO:0090611","GO:1902902","GO:0070676"]},{"accession":"XP_001328745.1","go_terms":["GO:0032147","GO:0042254"]},{"accession":"XP_001583726.1","go_terms":["GO:0071357","GO:0030850","GO:0046661","GO:0006463","GO:0006452","GO:0090084","GO:0006458","GO:0031204","GO:0006986","GO:0071374","GO:0001707","GO:0070843","GO:1901621","GO:0006260","GO:0070389","GO:0097428","GO:0006469","GO:0032781","GO:0006626","GO:0030433","GO:0009408","GO:0045454","GO:0036494","GO:0051259","GO:1900035","GO:0046825","GO:0035719","GO:0071630","GO:0034975"]},{"accession":"XP_001304583.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:1902187":1,"GO:0007076":1,"GO:0070676":1,"GO:1902902":1,"GO:0071454":1,"GO:0006620":1,"GO:0043328":1,"GO:0061763":1,"GO:1904669":1,"GO:0030713":1,"GO:0051301":1,"GO:0006915":1,"GO:1902188":1,"GO:0039702":1,"GO:0009838":1,"GO:1903541":1,"GO:0030447":1,"GO:0019058":1,"GO:0006997":1,"GO:0090148":1,"GO:0036258":1,"GO:0090611":1,"GO:0007080":1,"GO:0010458":1,"GO:0000920":1,"GO:0043162":1,"GO:1901673":1,"GO:0036438":1,"GO:0007049":1,"GO:0071985":1,"GO:0045053":1,"GO:1903723":1,"GO:0031468":1,"GO:2000641":1,"GO:0032147":1,"GO:0042254":1,"GO:0045454":1,"GO:0071357":1,"GO:0006458":1,"GO:0097428":1,"GO:0006626":1,"GO:0001707":1,"GO:0006469":1,"GO:0090084":1,"GO:0030850":1,"GO:0009408":1,"GO:1900035":1,"GO:0071630":1,"GO:0070389":1,"GO:0006986":1,"GO:0051259":1,"GO:0046661":1,"GO:0032781":1,"GO:0036494":1,"GO:0034975":1,"GO:0071374":1,"GO:0006463":1,"GO:0070843":1,"GO:0046825":1,"GO:1901621":1,"GO:0006260":1,"GO:0035719":1,"GO:0031204":1,"GO:0030433":1,"GO:0006452":1},"recipe_readded":["XP_001295673.1","XP_001325171.1","XP_001581820.1","XP_001328195.1","XP_001323021.1","XP_001316030.1","XP_001299588.1","XP_001312665.1","XP_001579543.1","XP_001309807.2","XP_001319751.1","XP_001307775.1","XP_001301989.1","XP_001319379.1","XP_001319431.1","XP_001311831.1","XP_001309838.1","XP_001579548.1","XP_001309663.1","XP_001322830.1"]}