{"hash":"1513954116175238838","title":"PKC-mediated lipid signaling and regulatory pathways","description":"The top GO terms point to lipid-second-messenger\u2013driven signaling (diacylglycerol metabolism and PIP2 catabolism) and direct involvement of protein kinase C signaling, along with various regulatory roles on signaling cascades (Ral, NF-kappaB, phosphorylation) and related biosynthetic processes. The set seems to capture a shared theme of modulating signaling activity via lipid signaling and phosphorylation rather than forming a single cohesive complex, hence a PKC-lipid signaling/regulatory cluster is most representative.","confidence":"Medium","size":5,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_001324710.1","go_terms":["GO:0038168","GO:2000182","GO:1990126","GO:0030033","GO:0043950","GO:0010801","GO:0034334","GO:0010667","GO:1901223","GO:0035021","GO:0019933","GO:0090557","GO:0070493","GO:0048022","GO:0000161","GO:0071880","GO:2000481","GO:0032835","GO:0060019","GO:1902634","GO:0051591","GO:0032486","GO:0032485","GO:0046339","GO:1902414","GO:0002291","GO:0050774","GO:0030949","GO:0071321","GO:0007205","GO:0070528","GO:0048009","GO:0046849","GO:2000670","GO:0046325","GO:0070507","GO:0070445","GO:2000064"]},{"accession":"XP_001300560.1","go_terms":[]},{"accession":"XP_051101382.1","go_terms":[]},{"accession":"XP_001317976.1","go_terms":["GO:0006295","GO:0006294","GO:0006296","GO:0006293","GO:0070816","GO:0006370","GO:0000717","GO:0006361","GO:0006363","GO:0006362","GO:0002031","GO:0070911","GO:0006366"]},{"accession":"XP_001327853.1","go_terms":[]}],"graph":[],"all_go_terms":{"GO:0051591":1,"GO:0046339":1,"GO:1902414":1,"GO:0032485":1,"GO:1902634":1,"GO:1901223":1,"GO:0010801":1,"GO:0048022":1,"GO:2000182":1,"GO:0070528":1,"GO:0019933":1,"GO:0030949":1,"GO:0070493":1,"GO:0010667":1,"GO:0046849":1,"GO:0000161":1,"GO:0046325":1,"GO:0032835":1,"GO:2000481":1,"GO:0071880":1,"GO:0043950":1,"GO:0060019":1,"GO:0071321":1,"GO:0007205":1,"GO:0050774":1,"GO:0032486":1,"GO:0034334":1,"GO:0090557":1,"GO:2000670":1,"GO:0038168":1,"GO:1990126":1,"GO:0035021":1,"GO:0070445":1,"GO:0070507":1,"GO:0030033":1,"GO:2000064":1,"GO:0048009":1,"GO:0002291":1,"GO:0006362":1,"GO:0006363":1,"GO:0006361":1,"GO:0006295":1,"GO:0006366":1,"GO:0006370":1,"GO:0006293":1,"GO:0000717":1,"GO:0070911":1,"GO:0002031":1,"GO:0070816":1,"GO:0006294":1,"GO:0006296":1},"recipe_readded":["XP_001293931.2","XP_001316599.1","XP_001307238.1","XP_001303910.1","XP_001300992.1","XP_001327571.1","XP_001314575.1","XP_001313147.1","XP_001309835.1","XP_001315568.1","XP_001326094.1","XP_001579747.1","XP_001322013.1","XP_001329447.1","XP_001319048.1","XP_001582336.1","XP_001319907.1","XP_001319274.1","XP_001312837.1"]}