{"hash":"1481476452933415984","title":"Ubiquitin-Proteasome and ERAD Regulation","description":"The top GO terms center on protein deubiquitination and sumoylation, signaling a cluster enriched for ubiquitin/SUMO modification processes and their regulation. This is complemented by terms related to ER-associated degradation (ERAD), autophagosome maturation control, and trafficking-related processes like endocytosis and GPCR internalization, all of which are connected to proteostasis and protein turnover. Although some terms (e.g., spindle pole body duplication, nucleotide-excision repair) are seemingly unrelated, they may reflect shared cellular machinery or annotation breadth; overall, the dominant theme ties to ubiquitin/SUMO-mediated quality control and degradation pathways.","confidence":"High","size":25,"edges":218,"triangles":1303,"max_degree":21,"top_function":"protein-containing complex 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