{"hash":"1424242222956393950","title":"TLR-MyD88 Calcium Signaling in Immunity","description":"The cluster centers on innate immune signaling (MyD88-dependent TLR signaling and TLR7 signaling) and pathways that drive calcium mobilization (phospholipase C-activating GPCR signaling and IP3 biosynthesis), suggesting a cohesive theme of TLR-driven immune responses linked to calcium signaling. Some other terms are obsolete or peripheral, but the core set points to this immune-calcium signaling axis.","confidence":"Medium","size":8,"edges":12,"triangles":6,"max_degree":5,"top_function":null,"members":[{"accession":"XP_001314595.1","go_terms":[]},{"accession":"XP_001308104.1","go_terms":[]},{"accession":"XP_001318641.1","go_terms":[]},{"accession":"XP_001329672.1","go_terms":["GO:0007100","GO:0036523","GO:0052014","GO:0007155","GO:1902769"]},{"accession":"XP_001581353.1","go_terms":[]},{"accession":"XP_001311913.1","go_terms":[]},{"accession":"XP_001582678.1","go_terms":[]},{"accession":"XP_001580175.1","go_terms":["GO:0009992","GO:0034158","GO:0060009","GO:0034154","GO:0032962","GO:0060065","GO:0042700","GO:0046544","GO:0071372","GO:0032350","GO:1905229","GO:0007189","GO:0045670","GO:0060011","GO:0001545","GO:0045087","GO:0060408","GO:0033148","GO:0071373","GO:0007190","GO:0050770","GO:0002755","GO:0051607","GO:0045779","GO:0045356","GO:0007200","GO:0035093","GO:0038194","GO:0042699","GO:1904588","GO:0010738"]}],"graph":[["XP_001581353.1","XP_001308104.1",0.959],["XP_001581353.1","XP_001318641.1",0.925],["XP_001581353.1","XP_001329672.1",0.851],["XP_001311913.1","XP_001308104.1",0.758],["XP_001311913.1","XP_001329672.1",0.951],["XP_001311913.1","XP_001582678.1",0.945],["XP_001318641.1","XP_001308104.1",0.555],["XP_001318641.1","XP_001582678.1",0.918],["XP_001318641.1","XP_001329672.1",0.938],["XP_001329672.1","XP_001582678.1",0.962],["XP_001580175.1","XP_001582678.1",0.853],["XP_001308104.1","XP_001582678.1",0.963]],"all_go_terms":{"GO:0007100":1,"GO:0007155":1,"GO:0052014":1,"GO:1902769":1,"GO:0036523":1,"GO:0045670":1,"GO:0002755":1,"GO:0007200":1,"GO:0032962":1,"GO:0034154":1,"GO:0060009":1,"GO:0042699":1,"GO:0046544":1,"GO:0001545":1,"GO:1905229":1,"GO:0007190":1,"GO:0038194":1,"GO:0071373":1,"GO:0034158":1,"GO:0071372":1,"GO:0060011":1,"GO:0010738":1,"GO:0060408":1,"GO:0060065":1,"GO:0051607":1,"GO:0045356":1,"GO:1904588":1,"GO:0042700":1,"GO:0032350":1,"GO:0045087":1,"GO:0007189":1,"GO:0035093":1,"GO:0033148":1,"GO:0009992":1,"GO:0050770":1,"GO:0045779":1},"recipe_readded":[]}