{"hash":"137037737866052330","title":"Protein folding and ER targeting under stress","description":"The dominant GO terms point to management of protein folding and targeting to membranes in the secretory pathway (unfolded protein response, SRP-dependent cotranslational targeting, chaperone-related refolding). This suggests a cluster centered on protein quality control and processing in the endoplasmic reticulum under stress. A few terms (DNA replication, karyogamy) appear unrelated, likely annotation noise, but do not define the core theme. ","confidence":"Medium","size":4,"edges":6,"triangles":4,"max_degree":3,"top_function":null,"members":[{"accession":"XP_001578973.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_001579928.1","go_terms":["GO:0000902","GO:0090084","GO:1903382","GO:1900035","GO:0000742","GO:0006880","GO:0016226","GO:1902037","GO:0070880","GO:0006260","GO:0034620","GO:0031204","GO:1903751","GO:0006616","GO:0070389"]},{"accession":"XP_001316215.1","go_terms":["GO:0055114","GO:0009231"]},{"accession":"XP_001304066.1","go_terms":[]}],"graph":[["XP_001316215.1","XP_001578973.1",0.963],["XP_001316215.1","XP_001579928.1",0.79],["XP_001316215.1","XP_001304066.1",0.962],["XP_001578973.1","XP_001579928.1",0.96],["XP_001578973.1","XP_001304066.1",0.684],["XP_001579928.1","XP_001304066.1",0.89]],"all_go_terms":{"GO:0034620":2,"GO:1900035":2,"GO:0006616":2,"GO:0006880":2,"GO:1903751":2,"GO:0006260":2,"GO:0000742":2,"GO:1902037":2,"GO:0070389":2,"GO:0016226":2,"GO:0090084":2,"GO:0031204":2,"GO:1903382":2,"GO:0070880":2,"GO:0000902":2,"GO:0055114":1,"GO:0009231":1},"recipe_readded":[]}