{"hash":"462974664518646244","title":"NF-kB and TLR inflammatory signaling inhibitors","description":"The cluster is characterized mainly by GO terms for negative regulation of NF-kappaB activity, suppression of TNF, IL-8, and IL-1 production, and negative regulation of TLR/LPS signaling, pointing to a core role in dampening inflammatory signaling through NF-kB and TLR pathways. A spliceosome-related term appears but does not define the cluster\u2019s function; overall, these proteins seem to act as anti-inflammatory regulators of NF-kB/TLR signaling.","confidence":"High","size":9,"edges":6,"triangles":0,"max_degree":6,"top_function":null,"members":[{"accession":"XP_065993632.1","go_terms":["GO:0071356","GO:0045292","GO:0034122","GO:0032088","GO:0032717","GO:0008595","GO:0032688","GO:0031665","GO:0071347","GO:0032720","GO:0071222"]},{"accession":"XP_065998769.1","go_terms":[]},{"accession":"XP_065998581.1","go_terms":[]},{"accession":"XP_025188989.1","go_terms":[]},{"accession":"XP_025182744.1","go_terms":[]},{"accession":"XP_065989527.1","go_terms":["GO:0010018","GO:0042753","GO:0009585"]},{"accession":"XP_025169732.1","go_terms":[]},{"accession":"XP_025175004.2","go_terms":[]},{"accession":"XP_025175274.2","go_terms":[]}],"graph":[["XP_065989527.1","XP_065993632.1",0.529],["XP_025169732.1","XP_065993632.1",0.565],["XP_025175274.2","XP_065993632.1",0.531],["XP_025175004.2","XP_065993632.1",0.589],["XP_065998769.1","XP_065993632.1",0.604],["XP_065993632.1","XP_025188989.1",0.664]],"all_go_terms":{"GO:0032088":1,"GO:0032720":1,"GO:0071222":1,"GO:0032717":1,"GO:0071347":1,"GO:0045292":1,"GO:0034122":1,"GO:0071356":1,"GO:0031665":1,"GO:0032688":1,"GO:0008595":1,"GO:0042753":1,"GO:0009585":1,"GO:0010018":1},"recipe_readded":[]}