{"hash":"2270071534895895320","title":"Neuronal proteostasis and stress signaling","description":"The cluster is dominated by ubiquitin-dependent proteolysis and SCF-mediated proteasomal degradation, with enrichment for protein ubiquitination and oxidative/toxin stress responses, plus neuron-related synaptic and apoptotic signaling terms. This points to a core theme of proteostasis and stress-response pathways in neural contexts, despite some broader cell-cycle terms that may be incidental.","confidence":"Medium","size":23,"edges":0,"triangles":0,"max_degree":0,"top_function":null,"members":[{"accession":"XP_025184335.2","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556","GO:0060386","GO:0031571","GO:0071406","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"XP_025180662.1","go_terms":[]},{"accession":"XP_025189307.2","go_terms":[]},{"accession":"XP_025177616.2","go_terms":[]},{"accession":"XP_025188770.1","go_terms":[]},{"accession":"XP_025187017.2","go_terms":[]},{"accession":"XP_025183924.2","go_terms":[]},{"accession":"XP_025184001.2","go_terms":[]},{"accession":"XP_025180639.1","go_terms":["GO:0060386","GO:0031571","GO:0071406","GO:0031146","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"XP_025181134.1","go_terms":[]},{"accession":"XP_025181536.2","go_terms":[]},{"accession":"XP_025178195.1","go_terms":[]},{"accession":"XP_025178844.2","go_terms":[]},{"accession":"XP_065989064.1","go_terms":[]},{"accession":"XP_066005055.1","go_terms":[]},{"accession":"XP_066003210.1","go_terms":["GO:0060386","GO:0031571","GO:0071406","GO:0031146","GO:1902916","GO:0071276","GO:0030174","GO:0042752","GO:1903378","GO:0042787","GO:0046685","GO:0000083","GO:0000209"]},{"accession":"XP_025166496.1","go_terms":[]},{"accession":"XP_025168653.2","go_terms":["GO:0035774","GO:0000423","GO:0032436","GO:0000266","GO:0099074","GO:0090201","GO:0033132","GO:0051865","GO:0043388","GO:0051583","GO:0036205","GO:0051412","GO:0023035","GO:0046329","GO:1903265","GO:0070936","GO:0090258","GO:0006986","GO:0070842","GO:0070979","GO:0048078","GO:0090141","GO:0010918","GO:0085020","GO:0042787","GO:1902283","GO:0071287","GO:1903427","GO:0070534","GO:0043123","GO:0060546","GO:0010636","GO:1903382","GO:2001171","GO:1902530","GO:0055069","GO:1905366","GO:0008344","GO:1903542","GO:0097039","GO:0010637","GO:0090394","GO:1904049","GO:0097237","GO:0042551","GO:0070050","GO:0006513","GO:1903378","GO:0051967","GO:0006351","GO:1903377","GO:0046676"]},{"accession":"XP_025169218.1","go_terms":[]},{"accession":"XP_025169460.1","go_terms":[]},{"accession":"XP_025172847.1","go_terms":[]},{"accession":"XP_025174086.2","go_terms":[]},{"accession":"XP_025175573.2","go_terms":["GO:0008285","GO:0070544","GO:0031146","GO:0046785","GO:0006516","GO:0007057","GO:0021678","GO:0021993","GO:0051436","GO:0001556"]}],"graph":[],"all_go_terms":{"GO:0030174":3,"GO:0042752":3,"GO:0008285":2,"GO:0021678":2,"GO:0071406":3,"GO:0060386":3,"GO:0046785":2,"GO:1902916":3,"GO:0046685":3,"GO:0031146":4,"GO:0021993":2,"GO:0031571":3,"GO:0000209":3,"GO:0051436":2,"GO:0006516":2,"GO:0001556":2,"GO:1903378":4,"GO:0071276":3,"GO:0070544":2,"GO:0000083":3,"GO:0007057":2,"GO:0042787":4,"GO:0006986":1,"GO:0070936":1,"GO:0042551":1,"GO:0070842":1,"GO:0070050":1,"GO:2001171":1,"GO:0070979":1,"GO:1903427":1,"GO:1903377":1,"GO:0055069":1,"GO:0010918":1,"GO:0051865":1,"GO:0090201":1,"GO:0036205":1,"GO:0090258":1,"GO:0090394":1,"GO:0097237":1,"GO:0035774":1,"GO:0085020":1,"GO:1904049":1,"GO:0051583":1,"GO:0010636":1,"GO:0051412":1,"GO:0043388":1,"GO:0090141":1,"GO:0060546":1,"GO:1902530":1,"GO:1903382":1,"GO:1902283":1,"GO:0008344":1,"GO:0097039":1,"GO:0046676":1,"GO:0032436":1,"GO:0006351":1,"GO:0010637":1,"GO:0000423":1,"GO:0051967":1,"GO:1905366":1,"GO:0000266":1,"GO:1903542":1,"GO:0006513":1,"GO:0070534":1,"GO:1903265":1,"GO:0043123":1,"GO:0099074":1,"GO:0048078":1,"GO:0023035":1,"GO:0033132":1,"GO:0046329":1,"GO:0071287":1},"recipe_readded":["XP_065991247.1","XP_025181584.1","XP_025180904.2","XP_025180014.2","XP_025182497.2","XP_065997907.1","XP_066000979.1","XP_025183382.2","XP_025180427.1","XP_066005290.1","XP_025188383.1","XP_025178258.2","XP_025168235.1","XP_025176507.1","XP_025174211.1","XP_025167866.1","XP_025175629.1","XP_065991629.1","XP_066005872.1","XP_066004744.1"]}